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Neuropsychologie psychischer Störungen pp 121–143Cite as

Psychoendokrine Aspekte neuropsychologischer Funktionen: Die Hypothalamus-Hypophysen-Nebennierenrinden-Achse

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Zusammenfassung

Der Patient P. leidet an einem Cushing-Syndrom. Sein Leben hat sich dramatisch verändert, seit aufgrund eines Tumors in seiner Hypophyse übermäßige Mengen der Stresshormone Kortikotropin (ACTH) und Kortisol freigesetzt werden. Äußerlich ist aus dem einst schlanken Mann ein fettleibiger Mensch geworden. Schlimmer für den Patienten P. sind die psychischen Auswirkungen der Hormonstörung. Seit Beginn der Krankheit ist er gereizt und leidet immer wieder unter depressiven Verstimmungen. Bei der Arbeit kann er sich nur mit Mühe konzentrieren, und sein Gedächtnis lässt ihn immer wieder im Stich. Erst seitdem sich der Patient P. einer Operation unterzogen hat, bei der der Tumor entfernt werden konnte, haben sich seine Hormonspiegel im Blut wieder normalisiert, und die psychischen Symptome haben sich deutlich gebessert.

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Authors and Affiliations

  1. Laboratory of Behavioral Neurology and Imaging of Cognition, University of Geneva, 1 rue Michel-Servet, CH-1211, Geneva

    Dr. Ullrich Wagner

  2. Medizinische Universität zu Lübeck, Ratzeburger Allee 160, 23562, Lübeck

    Prof. Dr. Jan Born

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  1. Dr. Ullrich Wagner
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  2. Prof. Dr. Jan Born
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Editors and Affiliations

  1. Lehrstuhl für Physiologische Psychologie, Otto-Friedrich-Universität Bamberg, Markusplatz 3, 96045, Bamberg

    Stefan Lautenbacher

  2. Institut für Medizinische Psychologie und Soziologie, RWTH Aachen, Pauwelsstraße 30, 52074, Aachen

    Siegfried Gauggel

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Wagner, U., Born, J. (2010). Psychoendokrine Aspekte neuropsychologischer Funktionen: Die Hypothalamus-Hypophysen-Nebennierenrinden-Achse. In: Lautenbacher, S., Gauggel, S. (eds) Neuropsychologie psychischer Störungen. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-72340-0_7

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