Auszug
Autoimmunität zählt zu den interessantesten Phänomenen, und das Wissen auf diesem Gebiet der Autoimmunerkrankungen hat in den letzten Jahren erhebliche Fortschritte gemacht. Aufgrund der Komplexität der Befunde muss von einer multifaktoriellen Genese ausgegangen werden, bei der neben genetischen Faktoren, zu denen HLA-Moleküle zählen, Hormone, Umwelteinflüsse, Chemikalien und Infektionen von Bedeutung sind. Charakterisiert werden können Autoimmunerkrankungen oftmals durch humorale oder zelluläre Immunreaktionen gegen körpereigene Gewebe. Zu ihrer Manifestation müssen verschiedene Faktoren zusammentreffen. Systemische Autoimmunerkrankungen sind oft schwer und lebensbedrohlich.
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Horneff, G., Wahn, V. (2007). Autoimmunerkrankungen. In: Reinhardt, D. (eds) Therapie der Krankheiten im Kindes- und Jugendalter. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-71899-4_43
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