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Handbook of Brain Connectivity pp 505–520Cite as

Large Scale Brain Dynamics and Connectivity in the Minimally Conscious State

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Part of the book series: Understanding Complex Systems ((UCS))

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References

  • Adams, J.H., Graham, D.I., Jennett, B. (2000) The neuropathology of the vegetative state after acute insult. Brain 123:1327–1338

    Article  Google Scholar 

  • Bekinschtein T, Leiguarda R, Armony J, Owen A, Carpintiero S, Niklison J, Olmos, L, Sigman L, Manes F.J (2004) Emotion processing in the minimally conscious state. J. Neurol Neurosurg Psychiatry 75(5):788

    Article  Google Scholar 

  • Bendat, M, Piersol, J.S. (2000) Random Data, McGraw-Hill Publishers, New York

    MATH  Google Scholar 

  • Boly M, Faymonville ME, Peigneux P, Lambermont B, Damas P, Del Fiore G, Degueldre C, Franck G, Luxen A, Lamy M, Moonen G, Maquet P, Laureys S. (2004) Auditory processing in severely brain injured patients: differences between the minimally conscious state and the persistent vegetative state. Arch Neurol. 61(2):233–8.

    Article  Google Scholar 

  • Boly, M, Faymonville ME, Peigneux P, Lambermont B, Damas P, Luxen A, Lamy M, Moonen G, Maquet P, Laureys S. (2005) Neuropsychological Rehabilitation 15:283–290

    Google Scholar 

  • Burruss JW, Chacko RC. (1999) Episodically remitting akinetic mutism following subarachnoid hemorrhage. J Neuropsychiatry Clin Neurosci 11(1):100–2

    Article  Google Scholar 

  • Caselli, R.J., Radford, N.R., Rezai, K., (1991) Thalamocortical diaschisis: single-photon emission tomographic study of cortical blood flow changes after focal thalamic infarction. Neuropsych. Neuropsych. Behav. Neurol. 4, 193–214.

    Google Scholar 

  • Chklovskii DB, Mel BW, Svoboda K. (2004) Cortical rewiring and information storage Nature. 431: 782–788

    Article  Google Scholar 

  • Clauss RP, van der Merwe CE, Nel HW. (2001) Arousal from a semi-comatose state on zolpidem. S Afr Med J. 91(10):788–9.

    Google Scholar 

  • Coleman MR, Menon DK, Fryer TD, Pickard JD. (2005) Neurometabolic coupling in the vegetative and minimally conscious states: preliminary findings. J Neurol Neurosurg Psychiatry. 76(3):432–4.

    Article  Google Scholar 

  • Crone NE, Boatman D, Gordon B, Hao L. (2001) Induced electrocorticographic gamma activity during auditory perception. Clin Neurophysiol. 112(4):565–82.

    Article  Google Scholar 

  • Dancause, N, Barbay, S, Frost, SB, Plautz, EJ, Chen, D, Zoubina, EV, Stowe, AV and Nudo, RJ (2005) Extensive Cortical Rewiring after Brain Injury. J. Neurosci. 25 10167–10179.

    Article  Google Scholar 

  • Elliott L, Coleman M, Shiel A, Wilson BA, Badwan D, Menon D, Pickard J. (2005) Effect of posture on levels of arousal and awareness in vegetative and minimally conscious state patients: a preliminary investigation. J Neurol Neurosurg Psychiatry. 76(2):298–9.

    Article  Google Scholar 

  • Fins, JJ. (2003) Constructing an ethical stereotaxy for severe brain injury: balancing risks, benefits and access. Nat Rev Neurosci. 4(4):323–7.

    Article  Google Scholar 

  • Fins, JJ. (2005) Clinical pragmatism and the care of brain damaged patients: toward a palliative neuroethics for disorders of consciousness. Prog Brain Res. 150:565–82.

    Article  Google Scholar 

  • Giacino, J.T., Ashwal, S., Childs, N., Cranford, R., Jennett, B., Katz, D.I., Kelly, J.P., Rosenberg, J.H., Whyte, J., Zafonte, R.D., Zasler, N.D., (2002). The minimally conscious state: definition and diagnostic criteria. Neurology 58, 349–53.

    Article  Google Scholar 

  • Gold, L., Lauritzen, M., (2002) Neuronal deactivation explains decreased cerebellar blood flow in response to focal cerebral ischemia or suppressed neocortical function. Proc. Natl. Acad. Sci. 99, 7699–704.

    Article  Google Scholar 

  • Hirsch J, Ruge MI, Kim KH, Correa DD, Victor JD, Relkin NR, Labar DR, Krol G, Bilsky MH, Souweidane MM, DeAngelis LM, Gutin PH. (2000) An integrated functional magnetic resonance imaging procedure for preoperative mapping of cortical areas associated with tactile, motor, language, and visual functions. Neurosurgery. 47(3):711–21.

    Google Scholar 

  • Jennett, B. (2002) The Vegetative State. Cambridge University Press.

    Google Scholar 

  • Jennett B., Adams, J.H., Murray, L.S. et al. (2001) Neuropathology in vegetative and severely disabled patients after head injury. Neurology 56: 486–490.

    Article  Google Scholar 

  • Jennett, B and Plum, F. (1972) Persistent vegetative state after brain damage. A syndrome in search of a name. Lancet 1: 734–7

    Google Scholar 

  • Kampfl A, Schmutzhard E, Franz G, Pfausler B, Haring HP, Ulmer H, Felber S, Golaszewski S, Aichner F. (1998) Prediction of recovery from post-traumatic vegetative state with cerebral magnetic-resonance imaging. Lancet 351(9118): 1763–7

    Article  Google Scholar 

  • Goldfine AM, Kobylarz, EJ, Hudson, AE, Giacino, JT, Hirsch, J and Schiff, ND (2005) Quantitative electroencephalography in a patient emerged from the minimally conscious state after 19 years. Society for Neuroscience 35$th$ Annual Meeting, Abstract

    Google Scholar 

  • Knyazeva MG, Innocenti GM. J (2001) EEG coherence studies in the normal brain and after early-onset cortical pathologies. Brain Res Brain Res Rev 36(2–3):119–28

    Article  Google Scholar 

  • Kobylarz, EJ, Hudson, AE, Kamal, A, DeBellis, R J, and Schiff, ND (2005) Power spectrum and coherence analysis of the electroencephalogram from two minimally conscious patients with severe asymmetric brain damage. Society for Neuroscience 35$th$ Annual Meeting, Abstract

    Google Scholar 

  • Kotchoubey B, Lang S, Mezger G, Schmalohr D, Schneck M, Semmler A, Bostanov V, Birbaumer N. (2005) Information processing in severe disorders of consciousness: vegetative state and minimally conscious state. Clin Neurophysiol. 116(10):2441–53.

    Article  Google Scholar 

  • Laureys, S., Faymonville, M.E., Degueldre, C., Fiore, G.D., Damas, P., Lambermont, B., Janssens, N., Aerts, J., Franck, G., Luxen, A., Moonen, G., Lamy, M., Maquet, P., (2000a) Auditory processing in the vegetative state. Brain 123,1589–601.

    Article  Google Scholar 

  • Laureys S, Faymonville ME, Peigneux P, Damas P, Lambermont B, Del Fiore G, Degueldre C, Aerts J, Luxen A, Franck G, Lamy M, Moonen G, Maquet P. Cortical processing of noxious somatosensory stimuli in the persistent vegetative state. Neuroimage 2002; 17(2): 732–41.

    Google Scholar 

  • Laureys, S.L., Owen, A.M., and Schiff, N.D. (2004) Brain function in coma, vegetative state and related disorders. Lancet Neurology 3(9):537–46.

    Article  Google Scholar 

  • Laureys S, Pellas F, Van Eeckhout P, Ghorbel S, Schnakers C, Perrin F, Berre J, Faymonville ME, Pantke KH, Damas F, Lamy M, Moonen G, Goldman S. (2005) The locked-in syndrome : what is it like to be conscious but paralyzed and voiceless? Prog Brain Res. 150:495–511.

    Article  Google Scholar 

  • Levy, DE, Sidtis, JJ, Rottenberg, DA, Jarden JO, Strother SC, Dhawan V, Ginos JZ, Tramo MJ, Evans AC, Plum F. (1987). Differences in cerebral blood flow and glucose utilization in vegetative versus locked-in patients. Ann Neurology 22, 673–82

    Article  Google Scholar 

  • McIntosh ARJ (2004) Contexts and catalysts: a resolution of the localization and integration of function in the brain. Neuroinformatics. 2(2):175–82.

    Article  Google Scholar 

  • McMillan TM, Herbert CM. (2004) Further recovery in a potential treatment withdrawal case 10 years after brain injury. Brain Inj. 18(9):935–40.

    Article  Google Scholar 

  • Mitra P.P., Pesaren, B. (1999) Analysis of dynamic brain imaging data. Biophysical Journal 76(2):691–708

    Article  Google Scholar 

  • NIH Consensus Development Panel on Rehabilitation of Persons with Traumatic Brain Injury JAMA 1999, 282(10): 974–983

    Google Scholar 

  • Owen, A, Coleman, M, Menon, D, Johnsrude, IS, Rodd, JM, Davis, MH, Taylor, K, Pickard, JD (2005) Residual auditory processing in persistent vegetative state: a combined PET and fMRI study. Neuropsychological Rehabilitation 15:290–307

    Article  Google Scholar 

  • Owen AM, Coleman MR, Menon DK, Berry EL, Johnsrude IS, Rodd JM, Davis MH, Pickard JD.(2005) Using a hierarchical approach to investigate residual auditory cognition in persistent vegetative state. Prog Brain Res. 150:457–71.

    Article  Google Scholar 

  • Plum, F., Posner, J. (1982) Diagnosis of Stupor and Coma. F.A. Davis and Company. New York..

    Google Scholar 

  • Repucci, M.A., Schiff, N.D., and Victor, J.D. (2001) General strategy for hierarchical decomposition of multivariate time series: implications for temporal lobe seizures. Annals of Biomedical Engineering 29(12):1135–49.

    Article  Google Scholar 

  • Rowe DL, Robinson PA, Rennie CJ. (2004) Estimation of neurophysiological parameters from the waking EEG using a biophysical model of brain dynamics. 231(3):413–33.

    Google Scholar 

  • Schiff, N.D. and Plum, F. (2000) The role of arousal and ‘gating’ systems in the neurology of impaired consciousness. Journal of Clinical Neurophysiology 17(5): 438–452.

    Article  Google Scholar 

  • Schiff, N., Ribary, U., Moreno, D., Beattie, B., Kronberg, E., Blasberg, R., Giacino, J., McCagg, C., Fins, J.J., Llinas, R. and Plum, F. (2002). Residual cerebral activity and behavioral fragments in the persistent vegetative state. Brain 125, 1210–1234.

    Article  Google Scholar 

  • Schiff, ND, Rodriguez-Moreno, D, Kamal, A, Kim, K.H., Giacino, J, Plum, F and Hirsch, J. (2005) fMRI reveals large-scale network activation in minimally conscious patients. Neurology 64: 514–523

    Article  Google Scholar 

  • Schiff, ND (2005) Modeling the minimally conscious state: measurements of brain function and therapeutic possibilities. Progress in Brain Research 150: 477–497

    Google Scholar 

  • Sporns O, Tononi G, Kotter R. (2005) The human connectome: a structural description of the human brain. PLoS Comput Biol. 1(4):e42.

    Article  Google Scholar 

  • Strauss DJ, Ashwal S, Day SM, Shavelle RM.(2000) Life expectancy of children in vegetative and minimally conscious states. 23(4):312–9.

    Google Scholar 

  • Szelies, B. et al. (1991) Widespread functional effects of discrete thalamic infarction. Arch Neurol. 48: 178–182.

    Article  Google Scholar 

  • Thatcher RW, North DM, Curtin RT, Walker R A, Biver CJ, Gomez JF, Salazar AM (2001) An EEG severity index of traumatic brain injury. Neuropsychiatry Clin Neurosci 13(1):77–87

    Article  Google Scholar 

  • Thatcher RW, Biver C, McAlaster R, Salazar A. (1998) Biophysical linkage between MRI and EEG coherence in closed head injury. Neuroimage 8(4):307–26

    Article  Google Scholar 

  • Tononi G. (2004) An information integration theory of consciousness. BMC Neurosci. 5(1):42

    Article  Google Scholar 

  • Walker MP, Ayre GA, Perry EK, Wesnes K, McKeith IG, Tovee M, Edwardson JA, Ballard CG. (2000) Quantification and characterization of fluctuating cognition in dementia with Lewy bodies and Alzheimer’s disease. Neurology 54:1616–1624.

    Article  Google Scholar 

  • Voss H.U., Ulug A.M., Watts R., Heier L.A., McCandliss B., Kobylarz E., Ballon D., Schiff N.D. (2005) Regional Increases in Diffusion Anisotropy in a Patient with Severe White Matter Atrophy after Traumatic Brain Injury: A Quantitative Diffusion Tensor Imaging Study, ISMRM 2005 abstract

    Google Scholar 

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Author information

Authors and Affiliations

  1. Weill Medical College of Cornell University, 1300 York Avenue, New York, 10021, USA

    Nicholas D Schiff

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  1. Nicholas D Schiff
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Editor information

Editors and Affiliations

  1. Theoretical Neuroscience Group UMR 6152 InstitutMouvement&Perception, CNRS, 163 av. de Luminy, CP910, F-13288 Marseille cedex 09, France

    Viktor K Jirsa

  2. Center for Complex Systems&Brain Sciences, Physics Department, Florida Atlantic University, Boca Raton, FL33431, Boca Raton, USA

    Viktor K Jirsa

  3. Rotman Research Institute Baycrest Centre, University of Toronto CIHR Scientist, 3560 Bathurst Street, Toronto, Ontario, M6A 2E1, Canada

    AR McIntosh

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© 2007 Springer-Verlag Berlin Heidelberg

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Schiff, N.D. (2007). Large Scale Brain Dynamics and Connectivity in the Minimally Conscious State. In: Jirsa, V.K., McIntosh, A. (eds) Handbook of Brain Connectivity. Understanding Complex Systems. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-71512-2_18

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