Abstract
This chapter reviews gynecological diseases associated with human papillomavirus (HPV) infection, particularly the terminology and grading of premalignant cervical lesions as well as general guidelines for the treatment of these disorders. The aim is to provide updated information that will help urologists and medical practitioners understand the diagnosis (including the different grading systems currently in use) and management of cervical intraepithelial neoplasia in the female partner. A full discussion of gynecological malignancies is beyond the scope of this book, and the interested reader should refer to specific literature. Cervical cancer is the second most common cancer among women worldwide and one of the leading causes of women’s death in developing countries (Parkin et al., 2005). Nevertheless, cervical premalignant conditions (also known as cervical intraepithelial neoplasia (CIN)) evolve slowly and these precancerous lesions can be discovered and treated before progression to invasive cervical carcinoma (ICC) occurs. Furthermore, in countries where organized cervical cancer surveillance has been implemented with a routine Papanicolaou (Pap) smear screening program, the ICC incidence and mortality have seen a dramatic reduction.
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Rosenblatt, A., de Campos Guidi, H.G. (2009). Human Papillomavirus and Cervical Intraepithelial Neoplasia. In: Human Papillomavirus. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-70974-9_8
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DOI: https://doi.org/10.1007/978-3-540-70974-9_8
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