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Cross-Calibration and Longitudinal Quality Control of Hologic Selenia Full-Field Digital Mammography Systems for Volumetric Breast Density Measurements

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Digital Mammography (IWDM 2008)

Part of the book series: Lecture Notes in Computer Science ((LNIP,volume 5116))

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Abstract

High breast tissue density has been shown to be one of the strongest predictors of breast cancer risk in women; though currently there are no calibrated methods to ensure that clinical measures of density are accurate. This inability to make accurate measurements impedes the use of breast tissue density as a cancer risk indicator. An accurate and precise method to measure the volumetric density of breast tissue in a clinical environment has been developed without modifying existing methods. The single x-ray absorptiometry (SXA) approach is validated against known breast fibroglandular density test phantoms and the accuracy and precision of the measure is monitored longitudinally. With cross-calibration and longitudinal quality control using the same test phantoms we show that SXA density measures are comparable between seven Hologic Selenia Full-Field Digital Mammography systems. In the future, we plan to address whether SXA measures can be generalized across different makes and models.

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Elizabeth A. Krupinski

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© 2008 Springer-Verlag Berlin Heidelberg

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Wang, J., Malkov, S., Fan, B., Shepherd, J. (2008). Cross-Calibration and Longitudinal Quality Control of Hologic Selenia Full-Field Digital Mammography Systems for Volumetric Breast Density Measurements. In: Krupinski, E.A. (eds) Digital Mammography. IWDM 2008. Lecture Notes in Computer Science, vol 5116. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-70538-3_102

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  • DOI: https://doi.org/10.1007/978-3-540-70538-3_102

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-70537-6

  • Online ISBN: 978-3-540-70538-3

  • eBook Packages: Computer ScienceComputer Science (R0)

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