Abstract
During the late foetal and perinatal period and during early infancy, major maturational processes and growth of the brain take place. Because of this ongoing maturation, the preterm brain in particular is very vulnerable to deviant development and damage. Patterns of perinatal brain injury depend not only on the origin of the injury (i.e. traumatic, hypoxic-ischaemic, inflammatory, haemorrhagic) but also on the PCA of the foetus or infant at the time of the event(s).
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References
Barkovich A, Truwit C (1990) Brain damage from perinatal asphyxia: correlation of MR findings with gestational age. AJNR Am J Neuroradiol 11:1087–1096
Barkovich AJ, Sargent SK (1995) Profound asphyxia in the premature infant: imaging findings. AJNR Am J Neuroradiol 16:1873–1846
Barkovich AJ et al. (1995) Perinatal asphyxia: MR findings in the first 10 days. AJNR Am J Neuroradiol 16:427–438
Battin M, Rutherford M (2002) Magnetic resonance of the brain in preterm infants: 24 weeks’ gestation to term. In: Rutherford M (ed) MRI of the neonatal brain. WB Saunders, London
Battin MR et al. (1998) Magnetic resonance imaging of the brain in very preterm infants: visualization of the germinal matrix, early myelination, and cortical folding. Pediatrics 101:957–962
Boxma A et al. (2005) Sonographic detection of the optic radiation. Acta Paediatr 94:1455–1461
Chi JG et al. (1977) Gyral development of the human brain. Ann Neurol 1:86–93
Childs AM et al. (2001) Cerebral maturation in premature infants: quantitative assessment using MR imaging. AJNR Am J Neuroradiol 22:1577–1582
Counsell SJ et al. (2002) MR imaging assessment of myelination in the very preterm brain. AJNR Am J Neuroradiol 23:872–881
Cowan F (2002) Magnetic resonance imaging of the normal infant brain: term to 2 years. In: Rutherford M (ed) MRI of the neonatal brain. WB Saunders, London
Davison AN, Dobbing J (1966) Myelination as a vulnerable period in brain development. Br Med Bull 22:40–44
De Vries LS et al. (1997) Infarcts in the vascular distribution of the middle cerebral artery in preterm and fullterm infants. Neuropediatrics 28:88–96
Horsch S et al. (2005) Ultrasound diagnosis of brain atrophy is related to neurodevelopmental outcome in preterm infants. Acta Paediatr 94:1815–1821
Huppi PS et al. (1996) Structural and neurobehavioral delay in postnatal brain development of preterm infants. Pediatr Res 39:895–901
Larroche J-C (1987) Le developpement du cerveau foetal humain. Atlas anatomique. INSERM CNRS, Paris
Leijser LM et al. (2004) Hyperechogenicity of the thalamus and basal ganglia in very preterm infants: radiological findings and short-term neurological outcome. Neuropediatrics 35:283–289
Maalouf EF et al. (1999) Magnetic resonance imaging of the brain in a cohort of extremely preterm infants. J Pediatr 135:351–357
Murphy NP et al. (1989) Cranial ultrasound assessment of gestational age in low birthweight infants. Arch Dis Child 64:569–572
Naidich TP et al. (1994) The developing cerebral surface. Preliminary report on the patterns of sulcal and gyral maturation – anatomy, ultrasound, and magnetic resonance imaging. Neuroimaging Clin N Am 4:201–240
Paneth N (1999) Classifying brain damage in preterm infants. J Pediatr 134:527–529
Rados M et al. (2006) In vitro MRI of brain development. Eur J Radiol 57:187–198
Sie LT et al. (1997) MRI assessment of myelination of motor and sensory pathways in the brain of preterm and term-born infants. Neuropediatrics 28:97–105
Soghier LM et al. (2006) Diffuse basal ganglia or thalamus hyperechogenicity in preterm infants. J Perinatol 26:230–236
Te Pas AB et al. (2005) Preoperative cranial ultrasound findings in infants with major congenital heart disease. Acta Paediatr 94:1597–1603
Van der Knaap MS, Valk J (2005) Myelination and retarded myelination. In: van der Knaap MS, Valk J (eds) Magnetic resonance of myelin, myelination, and myelin disorders. Springer, Berlin
Van der Knaap MS et al. (1996) Normal gyration and sulcation in preterm and term neonates: appearance on MR images. Radiology 200:389–396
Van Wezel-Meijler G et al. (1998) Magnetic resonance imaging of the brain in premature infants during the neonatal period. Normal phenomena and reflection of mild ultrasound abnormalities. Neuropediatrics 29:89–96
Van Wezel-Meijler G et al. (1999) Unilateral thalamic lesions in premature infants: risk factors and short-term prognosis. Neuropediatrics 30:300–306
Veyrac C et al. (2006) Brain ultrasonography in the premature infant. Pediatr Radiol 36:626–635
Volpe JJ (2001) Neuronal proliferation, migration, organization and myelination. In: Volpe JJ (ed) Neurology of the newborn. WB Saunders, Philadelphia
Yakovlev PI, Lecours AR (1967) The myelogenetic cycles of regional maturation of the brain. In: Minkowski A (ed) Regional development of the brain in early life. Blackwell, Oxford
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(2007). Maturational Changes of the Neonatal Brain. In: Neonatal Cranial Ultrasonography. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-69908-8_8
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DOI: https://doi.org/10.1007/978-3-540-69908-8_8
Publisher Name: Springer, Berlin, Heidelberg
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