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Regulation of the Cell Cycle by the Ubiquitin Pathway

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Book cover Cell Cycle Control

Part of the book series: Results and Problems in Cell Differentiation ((RESULTS,volume 22))

Abstract

Ubiquitin-mediated proteolysis is a major mechanism of regulation of cellular processes in which speed, specificity and timing are critical. Degradation of key substrates by the ubiquitin pathway controls cell cycle progression, circadian rhythms, cell fate commitment in development, signal transduction pathways, and immune responses (see Hochstrasser 1995 for review).

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  1. Department of Pathology and Kaplan Cancer Center, MSB 548, New York University Medical Center, 550 First Avenue, New York, New York, 10016, USA

    M. Pagano

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  1. J. Slingerland
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  1. Department of Pathology, MSB 548, New York University School of Medicine, 550 First Avenue, New York, NY, 10016, USA

    Michele Pagano

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Slingerland, J., Pagano, M. (1998). Regulation of the Cell Cycle by the Ubiquitin Pathway. In: Pagano, M. (eds) Cell Cycle Control. Results and Problems in Cell Differentiation, vol 22. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-69686-5_6

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