Topology Correction in Brain Segmentation Using a Multiscale Algorithm

  • Lin Chen
  • Gudrun Wagenknecht
Part of the Springer Proceedings in Physics book series (SPPHY, volume 114)


This is a new method for automatically correcting the spherical topology of a human brain segmentation under any digital connectivity. Topological correctness is important because it is an essential prerequisite for brain atlas deformation and surface flattening. A morphological multiscale approach which acts on foreground and background simultaneously divides the segmentation into several connected components, and subsequent region growing guarantees convergence to the correct spherical topology. In addition to existing graph-based procedures, this provides an alternate approach which has several advantages, including high speed and ease of operation without graph analysis and changing as few voxels as possible.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2007

Authors and Affiliations

  • Lin Chen
    • 1
  • Gudrun Wagenknecht
    • 1
  1. 1.Central Institute for ElectronicsResearch Center JuelichJuelichGermany

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