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Glaucoma in Infancy and Early Childhood

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Abstract

• Early identification of glaucoma in infants and children by physicians and care providers maximizes the likelihood of preserving useful vision.

• Glaucomas presenting in infancy share unique features related to the corneal and overall stretching of the eye under high intraocular pressure.

• Glaucomas presenting in older children sometimes take the form of refractive error, and their timely diagnosis may rely on careful scrutiny of the optic nerve head configuration and tonometry.

• All children with conditions predisposing to glaucoma should be regularly examined for glaucoma.

• Medical therapy is appropriate first-line therapy for many secondary glaucomas and to help clear the cornea for angle surgery in primary congenital glaucoma.

• Surgical intervention is essential for primary congenital glaucoma, and is often needed for other primary and secondary glaucomas inadequately controlled on medications.

• Successful care of childhood glaucoma requires ophthalmologists experienced in treating these rare conditions, but ultimately also requires a team approach including the family and child among other critical members.

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References

  1. Adachi M, Dickens CJ, Hetherington J Jr, Hoskins HD, Iwach AG, Wong PC, Nguyen N, Ma AS (1997) Clinical experience of trabeculotomy for the surgical treatment of aniridic glaucoma. Ophthalmology 104:2121–2125

    PubMed  CAS  Google Scholar 

  2. Ahn HC, Son HW, Kim JS, Lee JH (2005) Quantitative analysis of retinal nerve fiber layer thickness of normal children and adolescents. Korean J Ophthalmol 19:195–200

    PubMed  Google Scholar 

  3. Alfadhli S, Behbehani A, Elshafey A, Abdelmoaty S, Al-Awadi S (2006) Molecular and clinical evaluation of primary congenital glaucoma in Kuwait. Am J Ophthalmol 141:512–516

    PubMed  CAS  Google Scholar 

  4. Al Faran MF, Tomey KF, Al Mutlag FA (1990) Cyclocryotherapy in selected cases of congenital glaucoma. Ophthalmic Surg 21:794–798

    PubMed  CAS  Google Scholar 

  5. Alward WL (2000) Axenfeld-Rieger syndrome in the age of molecular genetics. Am J Ophthalmol 130:107–115

    PubMed  CAS  Google Scholar 

  6. Argus AA (1995) Ocular hypertension and central corneal thickness. Ophthalmology 102:1810–1812

    PubMed  CAS  Google Scholar 

  7. Arroyave CP, Scott IU, Gedde SJ, Parrish RK II, Feuer WJ (2003) Use of glaucoma drainage devices in the management of glaucoma associated with aniridia. Am J Ophthalmol 135:155–159

    PubMed  Google Scholar 

  8. Ausinsch B, Rayburn RL, Munson ES, Levy NS (1976) Ketamine and intraocular pressure in children. Anesth Analg 55:773–775

    PubMed  CAS  Google Scholar 

  9. Barkan O (1942) Operation for congenital glaucoma. Am J Ophthalmol 25:552

    Google Scholar 

  10. Barkan O (1955) Pathogenesis of congenital glaucoma: gonioscopic and anatomic observation of the angle of the anterior chamber in the normal eye and in congenital glaucoma. Am J Ophthalmol 40:1–11

    PubMed  CAS  Google Scholar 

  11. Beck AD, Freedman S, Kammer J, Jin J (2003) Aqueous shunt devices compared with trabeculectomy with mitomycin-C for children in the first two years of life. Am J Ophthalmol 136:994–1000

    PubMed  Google Scholar 

  12. Beck AD, Wilson WR, Lynch MG, Lynn MJ, Noe R (1998) Trabeculectomy with adjunctive mitomycin C in pediatric glaucoma. Am J Ophthalmol 126:648–657

    PubMed  CAS  Google Scholar 

  13. Becker B, Shaffer RN (1965) Diagnosis and therapy of the glaucomas. Mosby, St. Louis

    Google Scholar 

  14. Blumberg D, Congdon N, Jampel H, Gilbert D, Elliott R, Rivers R, Munoz B, Quigley H (2007) The effects of sevoflurane and ketamine on intraocular pressure in children during examination under anesthesia. Am J Ophthalmol 143:494–499

    PubMed  CAS  Google Scholar 

  15. Bock CJ, Freedman FF, Buckley EG, Shields MB (1997) Transscleral diode laser cyclophotocoagulation for refractory pediatric glaucomas. J Pediatr Ophthalmol Strabismus 34:235–239

    PubMed  CAS  Google Scholar 

  16. Brandt JD (2007) Central corneal thickness: tonometry artifact, or something more? Ophthalmology 114:1963–1964

    PubMed  Google Scholar 

  17. Brandt JD, Casuso LA, Budenz DL (2004) Markedly increased central corneal thickness: an unrecognized finding in congenital aniridia. Am J Ophthalmol 137:348–350

    PubMed  Google Scholar 

  18. Brown SM (1998) Increased iris pigment in a child due to latanoprost. Arch Ophthalmol 116:1683–1684

    PubMed  CAS  Google Scholar 

  19. Budenz DL, Sakamoto D, Eliezer R, Varma R, Heuer DK (2000) Two-staged Baerveldt glaucoma implant for childhood glaucoma associated with Sturge-Weber syndrome. Ophthalmology 107:2105–2110

    PubMed  CAS  Google Scholar 

  20. Burian HM (1960) A case of Marfan’s syndrome with bilateral glaucoma with a description of a new type of operation for developmental glaucoma. Am J Ophthalmol 50:1187–1192

    PubMed  CAS  Google Scholar 

  21. Chandler PA, Grant WM (1965) Lectures in glaucoma. Lea and Febiger, Philadelphia

    Google Scholar 

  22. Chandler PA, Grant WM (1980) Glaucoma. Lea and Febiger, Philadelphia

    Google Scholar 

  23. Chen TC, Walton DS (1998) Goniosurgery for prevention of aniridic glaucoma. Trans Am Ophthalmol Soc 96:155–165; discussion 165–169

    Google Scholar 

  24. Chen TC, Walton DS (1999) Goniosurgery for prevention of aniridic glaucoma. Arch Ophthalmol 117:1144–1148

    PubMed  CAS  Google Scholar 

  25. Coleman AL, Smyth RJ, Wilson MR, Tam M (1997) Initial clinical experience with the Ahmed glaucoma valve implant in pediatric patients. Arch Ophthalmol 115:186–191

    PubMed  CAS  Google Scholar 

  26. Copt RP, Thomas R, Mermoud A (1999) Corneal thickness in ocular hypertension, primary open-angle glaucoma, and normal tension glaucoma. Arch Ophthalmol 117:14–16

    PubMed  CAS  Google Scholar 

  27. Dai E, Gunderson CA (2006) Pediatric central corneal thickness variation among major ethnic populations. J AAPOS 10:22–25

    PubMed  Google Scholar 

  28. Da Mata A, Burk SE, Netland PA, Baltatzis S, Christen W, Foster CS (1999) Management of uveitic glaucoma with Ahmed glaucoma valve implantation. Ophthalmology 106:2168–2172

    PubMed  CAS  Google Scholar 

  29. DeLuise VP, Anderson DR (1983) Primary infantile glaucoma (congenital glaucoma). Surv Ophthalmol 28:1–18

    PubMed  CAS  Google Scholar 

  30. Dominiguez A, Banos MS, Alvare MG, Contra GF, Quintela FB (1974) Intraocular pressure measurement in infants under general anesthesia. Am J Ophthalmol 78:110–116

    Google Scholar 

  31. Donahue SP, Porter A (2001) SITA visual field testing in children. J AAPOS 5:114

    PubMed  CAS  Google Scholar 

  32. Donahue SP, Keech RV, Munden P, Scott WE (1997) Baerveldt implant surgery in the treatment of advanced childhood glaucoma. J AAPOS 1:41–45

    PubMed  CAS  Google Scholar 

  33. Egbert JE, Wright MM, Dahlhauser KF, Keithahn MA, Letson RD, Summers CG (1995) A prospective study of ocular hypertension and glaucoma after pediatric cataract surgery. Ophthalmology 102:1098–1101

    PubMed  CAS  Google Scholar 

  34. Ehlers N, Sorensen T, Bramsen T, Poulsen EH (1976) Central corneal thickness in newborns and children. Acta Ophthalmol (Copenh) 54:285–290

    CAS  Google Scholar 

  35. Englert JA, Freedman SF, Cox TA (1999) The Ahmed valve in refractory pediatric glaucoma. Am J Ophthalmol 127:34–42

    PubMed  CAS  Google Scholar 

  36. Enyedi LB, Freedman SF (2001) Safety and efficacy of brimonidine in children with glaucoma. J AAPOS 5:281–284

    PubMed  CAS  Google Scholar 

  37. Enyedi LB, Freedman SF (2002) Latanoprost for the treatment of pediatric glaucoma. Surv Ophthalmol 47(suppl 1):S129–S132

    PubMed  Google Scholar 

  38. Farber MD, Fiscella R, Goldberg MF (1991) Aminocaproic acid versus prednisone for the treatment of traumatic hyphema. A randomized clinical trial. Ophthalmology 98:279

    PubMed  CAS  Google Scholar 

  39. Fellenbaum PS, Sidoti PA, Heuer DK, Mincker DS, Baerveldt G, Lee PP (1995) Experience with the Baerveldt implant in young patients with complicated glaucomas. J Glaucoma 4:91–97

    CAS  PubMed  Google Scholar 

  40. Freedman SF, McCormick K, Cox TA (1999) Mitomycin C-augmented trabeculectomy with postoperative wound modulation in pediatric glaucoma. J AAPOS 3:117–124

    PubMed  CAS  Google Scholar 

  41. Freedman SF, Rodriguez-Rosa RE, Rojas MC, Enyedi LB (2002) Goniotomy for glaucoma secondary to chronic childhood uveitis. Am J Ophthalmol 133:617–621

    PubMed  Google Scholar 

  42. Gollamudi SR, Traboulsi EI, Chamon W, Stark WJ, Maumenee IH (1994) Visual outcome after surgery for Peters’ anomaly. Ophthalmic Genet 15:31–35

    PubMed  CAS  Google Scholar 

  43. Grant WM, Walton DS (1968) Distinctive gonioscopic findings in glaucoma due to neurofibromatosis. Arch Ophthalmol 79:127–134

    PubMed  CAS  Google Scholar 

  44. Grant WM, Walton DS (1974) Progressive changes in the angle in congenital aniridia, with development of glaucoma. Am J Ophthalmol 78:842–847

    PubMed  CAS  Google Scholar 

  45. Hamush NG, Coleman AL, Wilson MR (1999) Ahmed glaucoma valve implant for management of glaucoma in Sturge-Weber syndrome. Am J Ophthalmol 128:758–760

    PubMed  CAS  Google Scholar 

  46. Harrison DA, Mullaney PB, Mesfer SA, Awad AH, Dhindsa H (1998) Management of ophthalmic complications of homocystinuria. Ophthalmology 105:1886–1890

    PubMed  CAS  Google Scholar 

  47. Henriques MJ, Vessani RM, Reis FA, de Almeida GV, Betinjane AJ, Susanna R Jr (2004) Corneal thickness in congenital glaucoma. J Glaucoma 13:185–188

    PubMed  Google Scholar 

  48. Herndon LW, Choudhri SA, Cox T, Damji KF, Shields MB, Allingham RR (1997) Central corneal thickness in normal, glaucomatous, and ocular hypertensive eyes. Arch Ophthalmol 115:1137–1141

    PubMed  CAS  Google Scholar 

  49. Herse P, Weiping Y (1993) Variation in corneal thickness with age in young New Zealanders. Acta Ophthalmol 71:360–364

    Article  CAS  Google Scholar 

  50. Hess DB, Asrani SG, Bhide MG, Enyedi LB, Stinnett SS, Freedman SF (2005) Macular and retinal nerve fiber layer analysis of normal and glaucomatous eyes in children using optical coherence tomography. Am J Ophthalmol 139:509–517

    PubMed  Google Scholar 

  51. Ho CL, Walton DS (2004) Goniosurgery for glaucoma secondary to chronic anterior uveitis: prognostic factors and surgical technique. J Glaucoma 13:445–449

    PubMed  Google Scholar 

  52. Hussein MA, Paysee EA, Bell NP, et al. (2004) Corneal thickness in children. Am J Ophthalmol 138:744–748

    PubMed  Google Scholar 

  53. Jaafar MS, Ghulamqadir AK (1993) Effect of oral chloral hydrate sedation on the intraocular pressure measurement. J Ped Ophthalmol Strabismus 30:372–376

    CAS  Google Scholar 

  54. Kakiuchi-Matsumoto T, Isashiki Y, Ohba N, Kimura K, Sonoda S, Unoki K (2001) Cytochrome P450 1B1 gene mutations in Japanese patients with primary congenital glaucoma (1). Am J Ophthalmol 131:345–350

    PubMed  CAS  Google Scholar 

  55. Kirwan JF, Shah P, Khaw PT (2002) Diode laser cyclophotocoagulation: role in the management of refractory pediatric glaucomas. Ophthalmology 109:316–323

    PubMed  Google Scholar 

  56. Kiskis AA, Markowitz SN, Morin JD (1985) Corneal diameter and axial length in congenital glaucoma. Can J Ophthalmol 20:93

    PubMed  CAS  Google Scholar 

  57. Kivlin JD, Fineman RM, Crandall AA, Olson RJ (1986) Peters’ anomaly as a consequence of genetic and nongenetic syndromes. Arch Ophthalmol 104:61

    PubMed  CAS  Google Scholar 

  58. Kupfer C, Kaiser-Kupfer MS (1979) Observations on the development of the anterior chamber angle with reference to the pathogenesis of congenital glaucomas. Am J Ophthalmol 88:424

    PubMed  CAS  Google Scholar 

  59. Leske MC, Heijl A, Hyman L, Bengtsson B, Dong L, Yang Z (2007) Predictors of long-term progression in the early manifest glaucoma trial. Ophthalmology 114:1965–1972

    PubMed  Google Scholar 

  60. Mandal AK (1999) Primary combined trabeculotomy-trabeculectomy for early-onset glaucoma in Sturge-Weber syndrome. Ophthalmology 106:1621–1627

    PubMed  CAS  Google Scholar 

  61. Mandal AK, Prasad K, Naduvilath TJ (1999) Surgical results and complications of mitomycin C-augmented trabeculectomy in refractory developmental glaucoma. Ophthalmic Surg Lasers 30:473–480

    PubMed  CAS  Google Scholar 

  62. Mandal AK, Gothwal VK, Bagga H, Nutheti R, Mansoori T (2003) Outcome of surgery on infants younger than 1 month with congenital glaucoma. Ophthalmology 110:1909–1915

    PubMed  Google Scholar 

  63. Mandal AK, Bhatia PG, Gothwal VK, Reddy VM, Sriramulu P, Prasad MS, John RK, Nutheti R, Shamanna BR (2002) Safety and efficacy of simultaneous bilateral primary combined trabeculotomy-trabeculectomy for developmental glaucoma. Indian J Ophthalmol 50:13–19

    PubMed  Google Scholar 

  64. Martin SN, Sutherland J, Levin AV, Klose R, Priston M, Heon E (2000) Molecular characterisation of congenital glaucoma in a consanguineous Canadian community: a step towards preventing glaucoma related blindness. J Med Genet 37:422–427

    PubMed  CAS  Google Scholar 

  65. Mashima Y, Suzuki Y, Sergeev Y, Ohtake Y, Tanino T, Kimura I, Miyata H, Aihara M, Tanihara H, Inatani M, Azuma N, Iwata T, Araie M (2001) Novel cytochrome P4501B1 (CYP1B1) gene mutations in Japanese patients with primary congenital glaucoma. Invest Ophthalmol Vis Sci 42:2211–2216

    PubMed  CAS  Google Scholar 

  66. Maumenee AE (1963) Further observations on the pathogenesis of congenital glaucoma. Am J Ophthalmol 55:1163–1176

    PubMed  CAS  Google Scholar 

  67. Miller MH, Rice NS (1991) Trabeculectomy combined with beta irradiation for congenital glaucoma. Br J Ophthalmol 75:584–590

    PubMed  CAS  Google Scholar 

  68. Minckler DS, Baerveldt G, Heuer DK, Quillen-Thomas B, Walonker AF, Weiner J (1987) Clinical evaluation of the Oculab Tono-Pen. Am J Ophthalmol 104:168–173

    PubMed  CAS  Google Scholar 

  69. Molteno AC, Ancker E, Van Biljon G (1984) Surgical technique for advanced juvenile glaucoma. Arch Ophthalmol 102:51–57

    PubMed  CAS  Google Scholar 

  70. Molteno ACB (1973) Children with advanced glaucoma treated by draining implants. S Afr Arch Ophthalmol 1:55–61

    Google Scholar 

  71. Morad Y, Craig ED, Kim YM, Abdolell M, Levin AV (2003) The Ahmed drainage implant in the treatment of pediatric glaucoma. Am J Ophthalmol 135:821–829

    PubMed  Google Scholar 

  72. Mrugacz M, Bakunowicz-Lazarczyk A (2005) Optical coherence tomography measurement of the retinal nerve fiber layer in normal and juvenile glaucomatous eyes. Ophthalmologica 219:80–85

    PubMed  Google Scholar 

  73. Mueller OT, Hartsfield JK Jr, Gallardo LA, Essig YP, Miller KL, Papenhausen PR, Tedesco TA (1991) Lowe oculocerebrorenal syndrome in a female with a balanced X;20 translocation: mapping of the X chromosome breakpoint. Am J Hum Genet 49:804–810

    PubMed  CAS  Google Scholar 

  74. Muir KW, Jin J, Freedman SF (2004) Central corneal thickness and its relationship to intraocular pressure in children. Ophthalmology 111:2220–2223

    PubMed  Google Scholar 

  75. Muir KW, Duncan L, Enyedi LB, Stinnett SS, Freedman SF (2006) Central corneal thickness in children: stability over time. Am J Ophthalmol 141:955–957

    PubMed  Google Scholar 

  76. Muir KW, Duncan L, Enyedi LB, Wallace DK, Freedman SF (2007) Central corneal thickness: congenital cataracts and aphakia. Am J Ophthalmol 144:502–506

    PubMed  Google Scholar 

  77. Mukhopadhyay A, Acharya M, Mukherjee S, Ray J, Choudhury S, Khan M, Ray K (2002) Mutations in MYOC gene of Indian primary open angle glaucoma patients. Mol Vis 8:442–448

    PubMed  CAS  Google Scholar 

  78. Murphy DF (1985) Anesthesia and intraocular pressure. Anesth Analg 64:520–530

    PubMed  CAS  Google Scholar 

  79. Neely DE, Plager DA (2001) Endocyclophotocoagulation for management of difficult pediatric glaucomas. J AAPOS 5:221–229

    PubMed  CAS  Google Scholar 

  80. Ohtake Y, Kubota R, Tanino T, Miyata H, Mashima Y (2000) Novel compound heterozygous mutations in the cytochrome P4501B1 gene (CYP1B1) in a Japanese patient with primary congenital glaucoma. Ophthalmic Genet 21:191–193

    PubMed  CAS  Google Scholar 

  81. Olsen KE, Huang AS, Wright MM (1998) The efficacy of goniotomy/trabeculotomy in early-onset glaucoma associated with the Sturge-Weber syndrome. J AAPOS 2:365–368

    PubMed  CAS  Google Scholar 

  82. O’Malley Schotthoefer E, Yanovitch TL, Freedman SF (2008) Aqueous drainage device surgery in refractory pediatric glaucoma. II. Ocular motility consequence. J AAPOS 12:40–45

    PubMed  Google Scholar 

  83. O’Malley Schotthoefer E, Yanovitch TL, Freedman SF (2007) Aqueous drainage device surgery in refractory pediatric glaucomas: I. Long-term outcomes. J AAPOS 12:33–39

    PubMed  Google Scholar 

  84. a. Online Mendelian Inheritance in Man OT Johns Hopkins University, Baltimore, MD. MIM Number: {106210}{Date last edited}: 8/13/2007. World Wide Web URL: http://www.ncbi.nlm.nih.gov/omim/

    Google Scholar 

  85. b. Online Mendelian Inheritance in Man OT Johns Hopkins University, Baltimore, MD. MIM Number: {137600}{Date last edited}: 8/13/2007. World Wide Web URL: http://www.ncbi.nlm.nih.gov/omim/

    Google Scholar 

  86. c. Online Mendelian Inheritance in Man OT Johns Hopkins University, Baltimore, MD. MIM Number: {604229} World Wide Web URL: http://www.ncbi.nlm.nih.gov/omim/

    Google Scholar 

  87. d. Online Mendelian Inheritance in Man OT Johns Hopkins University, Baltimore, MD. MIM Number: {122000}. World Wide Web URL: http://www.ncbi.nlm.nih.gov/omim/

    Google Scholar 

  88. e. Online Mendelian Inheritance in Man OT Johns Hopkins University, Baltimore, MD. MIM Number: {162200}World Wide Web URL: http://www.ncbi.nlm.nih.gov/omim/

    Google Scholar 

  89. f. Online Mendelian Inheritance in Man OT Johns Hopkins University, Baltimore, MD. MIM Number: {309000}World Wide Web URL: http://www.ncbi.nlm.nih.gov/omim/

    Google Scholar 

  90. Panicker SG, Reddy AB, Mandal AK, Ahmed N, Nagarajaram HA, Hasnain SE, Balasubramanian D (2002) Identification of novel mutations causing familial primary congenital glaucoma in Indian pedigrees. Invest Ophthalmol Vis Sci 43:1358–1366

    PubMed  Google Scholar 

  91. Papadopoulos M, Cable N, Rahi J, Khaw PT (2007) The British Infantile and Childhood Glaucoma (BIG) Eye Study. Invest Ophthalmol Vis Sci 48:4100–4106

    PubMed  Google Scholar 

  92. Parks MM, Johnson DA, Reed GW (1993) Long-term visual results and complications in children with aphakia. A function of cataract type. Ophthalmology 100:826–840; discussion 840–841

    Google Scholar 

  93. Passo MS, Palmer EA, Van Buskirk EM (1984) Plasma timolol in glaucoma patients. Ophthalmology 91:1361–1363

    PubMed  CAS  Google Scholar 

  94. Payne MS, Nadell JM, Lacassie Y, Tilton AH (2003) Congenital glaucoma and neurofibromatosis in a monozygotic twin: case report and review of the literature. J Child Neurol 18:504–508

    PubMed  Google Scholar 

  95. Pensiero S, DaPozza S, Perissutti P, Cavallini GM, Guerra R (1992) Normal intraocular pressure in children. J Pediatr Ophthalmol Strabismus 29:79–84

    PubMed  CAS  Google Scholar 

  96. Phelan MJ, Higginbotham EJ (1995) Contact transscleral Nd:YAG laser cyclophotocoagulation for the treatment of refractory pediatric glaucoma. Ophthalmic Surg Lasers 26:401–403

    PubMed  CAS  Google Scholar 

  97. Phelps CD (1978) The pathogenesis of glaucoma in Sturge-Weber syndrome. Ophthalmology 85:276–286

    PubMed  CAS  Google Scholar 

  98. Phelps CD, Podos SM (1974) Glaucoma. Little Brown, Boston

    Google Scholar 

  99. Plager DA, Neely DE (1999) Intermediate-term results of endoscopic diode laser cyclophotocoagulation for pediatric glaucoma. J AAPOS 3:131–137

    PubMed  CAS  Google Scholar 

  100. Reddy AB, Kaur K, Mandal AK, Panicker SG, Thomas R, Hasnain SE, Balasubramanian D, Chakrabarti S (2004) Mutation spectrum of the CYP1B1 gene in Indian primary congenital glaucoma patients. Mol Vis 10:696–702

    PubMed  CAS  Google Scholar 

  101. Richardson KT (1968) Optic cup symmetry in normal newborn infants. Invest Ophthalmol 7:137–147

    PubMed  CAS  Google Scholar 

  102. Salchow DJ, Oleynikov YS, Chiang MF, Kennedy-Salchow SE, Langton K, Tsai JC, Al-Aswad LA (2006) Retinal nerve fiber layer thickness in normal children measured with optical coherence tomography. Ophthalmology 113:786–791

    PubMed  Google Scholar 

  103. Sampaolesi R, Caruso R (1982) Ocular echometry in the diagnosis of congenital glaucoma. Arch Ophthalmol 100:574–577

    PubMed  CAS  Google Scholar 

  104. Sarfarazi M (1997) Recent advances in molecular genetics of glaucomas. Hum Mol Genet 6:1667–1677

    PubMed  CAS  Google Scholar 

  105. Sarfarazi M, Akarsu AN, Hossain A, Turacli ME, Aktan SG, Barsoum-Homsy M, Chevrette L, Sayli BS (1995) Assignment of a locus (GLC3A) for primary congenital glaucoma (buphthalmos) to 2p21 and evidence for genetic heterogeneity. Genomics 30:171–177

    PubMed  CAS  Google Scholar 

  106. Sena DF, Finzi S, Rodgers K, Del Bono E, Haines JL, Wiggs JL (2004) Founder mutations of CYP1B1 gene in patients with congenital glaucoma from the United States and Brazil. J Med Genet 41:e6

    PubMed  CAS  Google Scholar 

  107. Shaffer RN, Heatherington J (1969) Glaucomatous disc in infants. A suggested hypothesis for disc cupping. Trans Am Acad Ophthalmol Otolaryngol 73:929–935

    Google Scholar 

  108. Shields MB, Buckley EG, Klintworth GK, Thresher R (1985) Axenfeld-Rieger syndrome. A spectrum of developmental disorders. Surv Ophthalmol 29:387

    PubMed  CAS  Google Scholar 

  109. Sidoti PA, Belmonte SJ, Liebmann JM, Ritch R (2000) Trabeculectomy with mitomycin C in the treatment of pediatric glaucomas. Ophthalmology 107:422–429

    PubMed  CAS  Google Scholar 

  110. Simon JW, O’Malley MR, Gandham SB, Ghaiy R, Zobal-Ratner J, Simmons ST (2005) Central corneal thickness and glaucoma in aphakic and pseudophakic children. J AAPOS 9:326–329

    PubMed  Google Scholar 

  111. Simsek T, Mutluay AH, Elgin U, Gursel R, Batman A (2006) Glaucoma and increased central corneal thickness in aphakic and pseudophakic patients after congenital cataract surgery. Br J Ophthalmol 90:1103–1106

    PubMed  CAS  Google Scholar 

  112. Sitorus R, Ardjo SM, Lorenz B, Preising M (2003) CYP1B1 gene analysis in primary congenital glaucoma in Indonesian and European patients. J Med Genet 40:e9

    PubMed  CAS  Google Scholar 

  113. Smith R (1960) A new technique for opening the canal of Schlemm. Br J Ophthalmol 44:370–373

    PubMed  CAS  Google Scholar 

  114. Soley GC, Bosse KA, Flikier D, Flikier P, Azofeifa J, Mardin CY, Reis A, Michels-Rautenstrauss KG, Rautenstrauss BW (2003) Primary congenital glaucoma: a novel single-nucleotide deletion and varying phenotypic expression for the 1,546-1,555dup mutation in the GLC3A (CYP1B1) gene in 2 families of different ethnic origin. J Glaucoma 12:27–30

    PubMed  Google Scholar 

  115. Stoilov IR, Costa VP, Vasconcellos JP, Melo MB, Betinjane AJ, Carani JC, Oltrogge EV, Sarfarazi M (2002) Molecular genetics of primary congenital glaucoma in Brazil. Invest Ophthalmol Vis Sci 43:1820–1827

    PubMed  Google Scholar 

  116. Stone DL, Fingert JH, Alward WL, et al. (1997) Identification of a gene that causes primary open angle glaucoma. Science 275:668–670

    PubMed  CAS  Google Scholar 

  117. Susanna RJ, Oltrogge EW, Carani JCE, Nicolela MT (1995) Mitomycin as adjunct chemotherapy with trabeculectomy in congenital and developmental glaucomas. J Glaucoma 4:151–157

    PubMed  Google Scholar 

  118. Tai TY, Mills MD, Beck AD, Joos KM, Ying GS, Liu C, Piltz-Seymour JR (2006) Central corneal thickness and corneal diameter in patients with childhood glaucoma. J Glaucoma 15:524–528

    PubMed  Google Scholar 

  119. Turleau C, DeGrouchy J, Tournade M-F, et al. (1984) Del 11p/aniridia complex. Report of three patients and review of 37 observations from the literature. Clin Genet 26:356

    Article  PubMed  CAS  Google Scholar 

  120. Van Buskirk EM, Plamer EA (1979) Office assessment of young children for glaucoma. Ann Ophthalmol 11:1749

    PubMed  Google Scholar 

  121. van Emelen C, Goethals M, Dralands L, Casteels I (2000) Treatment of glaucoma in children with Sturge-Weber syndrome. J Pediatr Ophthalmol Strabismus 37:29–34

    PubMed  Google Scholar 

  122. Vincent AL, Billingsley G, Buys Y, Levin AV, Priston M, Trope G, Williams-Lyn D, Heon E (2002) Digenic inheritance of early-onset glaucoma: CYP1B1, a potential modifier gene. Am J Hum Genet 70:448–460

    PubMed  CAS  Google Scholar 

  123. Waardenburg PJ, Franceschetti P, Klein D (1961) Genetics and ophthalmology. Thomas, Springfields

    Google Scholar 

  124. Wagle NS, Freedman SF, Buckley EG, Davis JS, Biglan AW (1998) Long-term outcome of cyclocryotherapy for refractory pediatric glaucoma. Ophthalmology 105:1921–1926; discussion 1926–1927

    Google Scholar 

  125. Walton DS (1979) Primary congenital open-angle glaucoma. In: Chandler PA, Grant WM (eds) Glaucoma. Lea and Febiger, Philadelphia, p 329

    Google Scholar 

  126. Walton DS (1979) Primary congenital open angle glaucoma: a study of the anterior segment abnormalities. Trans Am Ophthalmol Soc 77:746–768

    PubMed  CAS  Google Scholar 

  127. Walton DS (1986) Diagnosis and treatment of glaucoma in childhood. In: Epstein DL (ed) Chandler and Grant’s Glaucoma. Lea and Febinger, Philadelphia

    Google Scholar 

  128. Walton DS (1991) Glaucoma in infants and children. In: Nelson LB, Calhoun JH, Harley RD (eds) Pediatric ophthalmology. Saunders, Philadelphia, pp 258–270

    Google Scholar 

  129. Walton DS (1995) Pediatric aphakic glaucoma: a study of 65 patients. Trans Am Ophthalmol Soc 93:403–413; discussion 413–420

    Google Scholar 

  130. Watcha MF, Chu FC, Stevens JL, Forestner JE (1990) Effects of halothane on intraocular pressure in anesthetized children. Anesth Analg 71:181–184

    PubMed  CAS  Google Scholar 

  131. Wells AP, Cordeiro MF, Bunce C, Khaw PT (2003) Cystic bleb formation and related complications in limbus- versus fornix-based conjunctival flaps in pediatric and young adult trabeculectomy with mitomycin C. Ophthalmology 110:2192–2197

    PubMed  Google Scholar 

  132. Wiggins RE Jr, Tomey KF (1992) The results of glaucoma surgery in aniridia. Arch Ophthalmol 110:503–505

    PubMed  Google Scholar 

  133. Wright MM, McGehee RF, Pederson JE (1997) Intraoperative mitomycin-C for glaucoma associated with ocular inflammation. Ophthalmic Surg Lasers 28:370–376

    PubMed  CAS  Google Scholar 

  134. Yang LL, Lambert SR (2001) Peters’ anomaly. A synopsis of surgical management and visual outcome. Ophthalmol Clin North Am 14:467–477

    PubMed  CAS  Google Scholar 

  135. Zaidman GW, Rabinowitz Y, Forstot SL (1998) Optical iridectomy for corneal opacities in Peters’ anomaly. J Cataract Refract Surg 24:719–722

    PubMed  CAS  Google Scholar 

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Freedman, S., Johnston, S. (2009). Glaucoma in Infancy and Early Childhood. In: Wilson, M., Trivedi, R., Saunders, R. (eds) Pediatric Ophthalmology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-68632-3_24

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