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Hirntumoren

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NeuroIntensiv

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Hirntumoren treten entweder als primäre Erkrankungen des Nervensystems oder sekundär als Komplikation metastatischer, primär extrazerebraler Tumorerkrankungen auf. Die Prognose der primären Tumoren ist in Abhängigkeit von Histologie und Erkrankungsalter sehr unterschiedlich. Etwa 20% aller Patienten mit extrazerebralen Tumoren entwickeln Hirnmetastasen. Diese tragen erheblich zur Morbidität bei und sind eine häufige Todesursache.

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Literatur

  1. Anderson GD, Lin YX, Berge C, Ojemann GA (1997) Absence of bleeding complications in patients undergoing cortical surgery while receiving valproate treatment. J Neurosurg 87:252–256

    Article  PubMed  CAS  Google Scholar 

  2. Davis FG, McCarthy BJ, Freels S, Kupelian V, Bondy ML (1999) The conditional probability of survival of patients with primary malignant brain tumors. Surveillance, epidemiology, and end results (SEER) data. Cancer 85:485–491

    Article  PubMed  CAS  Google Scholar 

  3. DeAngelis LM (2001) Brain tumors. N Engl J Med 344:114–122

    Article  PubMed  CAS  Google Scholar 

  4. Deutsche Gesellschaft für Neurologie (Diener HC, Putzki N, Berlit P, Hrsg.). Leitlinien für Diagnostik und Therapie in der Neurologie. Thieme, Stuttgart, 2005

    Google Scholar 

  5. Deutsche Krebsgesellschaft. Neuro-Onkologische Arbeitsgemeinschaft (NOA) in der Deutschen Krebsgesellschaft. Leitlinie Diagnostik und Therapie der Gliome des Erwachsenenalters. www.neuroonkologie. de, Zuckschwerdt, München, 2004

    Google Scholar 

  6. Glantz MJ, Cole BF, Forsyth PA, Recht LD, Wen PY, Chamberlain MC, Grossman SA, Cairncross JG (2000) Practice parameter: anticonvulsant prophylaxis in patients with newly diagnosed brain tumors. Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 54:1886–1893

    PubMed  CAS  Google Scholar 

  7. Kalfas IH, Little JR (1988) Postoperative hemorrhage: a survey of 4992 intracranial procedures. Neurosurgery 23:343–347

    Article  PubMed  CAS  Google Scholar 

  8. Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A, Scheithauer B, Kleihues P (2007) WHO Classification of Tumours of the Central Nervous System. IARC Press, Lyon

    Google Scholar 

  9. Leonard IE, Cunningham AJ (2002) The sitting position in neurosurgery-not yet obsolete! Br J Anaesth 88:1–3

    Article  PubMed  CAS  Google Scholar 

  10. Macdonald DR, Cascino TL, Schold SC, Cairncross JG (1990) Response criteria for phase II studies of supratentorial malignant glioma. J Clin Oncol 8:1277–1280

    PubMed  CAS  Google Scholar 

  11. Pels H, Schmidt-Wolf IGH, Glasmacher A, Schulz H, Engert A, Diehl V, Zellner A, Schackert G, Reichmann H, Kroschinsky F, Vogt-Schaden M, Egerer G, Bode U, Schaller S, Deckert M, Fimmers R, Helmstaedter C, Atasoy A, Klockgether T, Schlegel U (2003) Primary CNS lymphoma: Results of a pilot/phase II study of systemic and intraventricular chemotherapy with deferred radiotherapy. J Clin Oncol 21:4489–4495

    Article  PubMed  CAS  Google Scholar 

  12. Sawaya R, Hammoud M, Schoppa D, Hess KR, Wu SZ, Shi WM, Wildrick DM (1998) Neurosurgical outcomes in a modern series of 400 craniotomies for treatment of parenchymal tumors. Neurosurgery 42:1044–1055

    Article  PubMed  CAS  Google Scholar 

  13. Schlegel U, Weller M, Westphal M (Hrsg.) (2003) Neuroonkologie. Thieme Verlag. Stuttgart

    Google Scholar 

  14. Stummer W, Pichlmeier U, Meinel T, Wiestler O, Zanella F, Reulen R, for the ALA-Glioma Study Group (2006) Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial. Lancet Oncology 7:392–401

    Article  PubMed  CAS  Google Scholar 

Literatur

  1. Andrews DW, Scott CB, Sperduto PW, Flanders AE, Gaspar LE, Schell MC, Werner-Wasik M, Demas W, Ryu J, Bahary JP, Souhami L, Rotman M, Mehta MP, Curran WJ Jr. (2004) Whole brain radiation therapy with or without stereotactic radiosurgery boost for patients with one to three brain metastases: phase III results of the RTOG 9508 randomised trial. Lancet 363:1665–1672

    Article  PubMed  Google Scholar 

  2. Maranzano E, Bellavita R, Rossi R, De Angelis V, Frattegiani A, Bagnoli R, Mignogna M, Beneventi S, Lupattelli M, Ponticelli P, Biti GP, Latini P (2005) Short-course versus split-course radiotherapy in metastaticspinal cord compression. Results of a phase III, randomized, multicenter trial. J Clin Oncol 23:3358–3365

    Article  PubMed  Google Scholar 

  3. Deutsche Gesellschaft für Neurologie (Diener HC, Putzki N, Berlit P, Hrsg.). Leitlinien für Diagnostik und Therapie in der Neurologie. Thieme, Stuttgart, 2005

    Google Scholar 

  4. Deutsche Krebsgesellschaft. Leitlinien der Neuro-Onkologischen Arbeitsgemeinschaft (NOA) in der Deutschen Krebsgesellschaft zu Hirnmetastasen und Meningeosis neoplastica (http://www.neuroonkologie.de)

    Google Scholar 

  5. Mintz AH, Kestle J, Rathbone MP, Gaspar L, Hugenholtz H, Fisher B, Duncan G, Skingley P, Foster G, Levine M (1996) A randomized trial to assess the efficacy of surgery in addition to radiotherapy in patients with a single cerebral metastasis. Cancer 78:1470–1476

    Article  PubMed  CAS  Google Scholar 

  6. Obbens EAMT, Leavens ME, Beal JW, Lee Y (1985) Ommaya reservoir in 387 cancer patients: a 15-year experience. Neurology 35:1274–1278

    PubMed  CAS  Google Scholar 

  7. Patchell RA, Tibbs PA, Walsh JW, Dempsey RJ, Maruyama Y, Kryscio RJ, Markesbery WR, Macdonald JS, Young B (1990) A randomized trial of surgery in the treatment of single metastases to the brain. N Engl J Med 322:494–500

    PubMed  CAS  Google Scholar 

  8. Patchell RA, Tibbs PA, Regine WF, Dempsey RJ, Mohiuddin M, Kryscio RJ, Markesbery WR, Foon KA, Young B (1998) Postoperative radiotherapy in the treatment of single metastases to the brain. A randomized trial. J Am Med Assoc 280:1485–1489

    Article  CAS  Google Scholar 

  9. Patchell RA, Tibbs PA, Regine WF, Payne R, Saris S, Kryscio RJ, Mohiuddin M, Young B (2005) Direct decompressive surgical resection in the treatment of spinal cord compression caused by metastatic cancer. A randomized trial. Lancet 366:643–648

    Article  PubMed  Google Scholar 

  10. Schellinger PD, Meinck HM, Thron A. Diagnostic reach of mri compared to cct in patients with brain metastases. J Neuro-Oncol. 1999;44:275–281

    Article  CAS  Google Scholar 

  11. Schlegel U, Weller M, Westphal M (Hrsg.) (2003) Neuroonkologie. Thieme Verlag. Stuttgart

    Google Scholar 

  12. Shaw EG, Scott C, Souhami L, Dinapoli R, Kline R, Loeffler J, Farnan N (2000) Single dose radiosurgical treatment of recurrent previously irradiated primary brain tumors and brain metastases: final report of RTOG protocol 90-05. Int J Radiat Oncol Biol Phys 47:291–298

    Article  PubMed  CAS  Google Scholar 

  13. Vecht CJ, Haaxma-Reiche H, Noordijk EM, Padberg GW, Voormolen JHC, Hoekstra FH, Tans JTJ, Lambooij N, Metsaars JAL, Wattendorff AR, Brand R, Hermans J (1993) Treatment of single brain metastasis: radiotherapy alone or combined with neurosurgery? Ann Neurol 33:583–590

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Neurologische Klinik, Universitätsspital Zürich, Frauenklinikstrasse 26, CH-8091, Zürich

    Prod. Dr. M. Weller

  2. Neurologische Universitätsklinik, Knappschaftskrankenhaus Langendreer, Ruhr-Universität Bochum, In der Schornau 23-25, 44892, Bochum

    Prof. Dr. U. Schlegel

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  1. Prod. Dr. M. Weller
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Editors and Affiliations

  1. Neurologische Klinik, Friedrich-Alexander-Universität Erlangen-Nürnberg, Schwabachanlage 6, 91054, Erlangen

    Stefan Schwab  & Peter Schellinger  & 

  2. Klinik für Anästhesiologie, Klinikum der Johannes Gutenberg-Universität Mainz, Langenbeckstr. 1, 55131, Mainz

    Christian Werner

  3. Neurochirurgische Klinik, Ruprecht-Karls-Universität Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg

    Andreas Unterberg  & Werner Hacke  & 

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Weller, M., Schlegel, U. (2008). Hirntumoren. In: Schwab, S., Schellinger, P., Werner, C., Unterberg, A., Hacke, W. (eds) NeuroIntensiv. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-68317-9_37

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  • DOI: https://doi.org/10.1007/978-3-540-68317-9_37

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-23051-9

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