Abstract
Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide, due to its high rate of incidence in Africa (south of the Sahara), and a high association with hepatitis viruses (HBV and HCV), consumption of alcohol, aflatoxin B1, and hepatic cirrhosis (Bruix et al. 1991). The incidence of HCC has increased both because of a real increase in the occurrence of the disease, and because modern imaging techniques allow diagnosis at an earlier stage of disease. Surgical resection and liver transplantation remain the most effective treatment strategies for small and oligonodular (five or fewer intrahepatic lesions) HCCs. Some studies yield excellent survival rates using percutaneous ethanol injection (PEI) (Bruix et al. 1991; Sironi et al. 1991, 1993; Amin et al. 1993; Livraghi et al. 1995; Kawai et al. 1997).
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References
Amin Z, Donald JJ, Masters A et al (1993a) Hepatic metastases: interstitial laser photocoagulation with real-time US monitoring and dynamic CT evaluation of treatment. Radiology 187:339–347
Amin Z, Bown SG, Lees WR (1993b) Local treatment of colorectal liver metastases: a comparison of interstitial laser photocoagulation (ILP) and percutaneous alcohol injection (PAI). Clin Radiol 48:166–171
Anzai Y, Lufkin RB, Castro DJ et al (1991) MR imaging-guided interstitial Nd:YAG laser phototherapy: dosimetry study of acute tissue damage in an in vivo model. J Magn Reson Imaging 1:553–559
Bismuth H, Chiche L, Adam R, Castaing D, Diamond T, Dennison A (1993) Liver resection versus transplantation for hepatocellular carcinoma in cirrhotic patients. Ann Surg 218:145–151
Bruix J, Castells A, Bru C (1991) Caracteristicas clinicas y prognostico del carcinoma hepatocelular. Existen difirencias geograficas? Gastroenterol Hepatol 14:520–524
Dickinson RJ, Hall AS, Hind AJ, Young IR (1986) Measurement of changes in tissue temperature using MR imaging. J Comput Assist Tomogr 10:468–472
Jolesz FA, Bleier AR, Jakab P, Ruenzel PW, Huttl K, Jako GJ (1988) MR imaging of laser-tissue interactions. Radiology 168:249–253
Kanematsu T, Matsumata T, Shirabe K (1993) A comparative study of hepatic resection and transcatheter arterial embolization for the treatment of primary hepatocellular carcinoma. Cancer 71:2181–2186
Kawai S, Tani M, Okumura J, Ogawa M et al (1997) Prospective and randomized clinical trial of lipiodol-transcatheter arterial chemoembolization for treatment of hepatocellular carcinoma: a comparison of epirubicin and doxorubicin (second cooperative study). Semin Oncol 24:38–45
Livraghi T, Giorgio A, Marin G et al (1995) Hepatocellular carcinoma and cirrhosis in 746 patients: long-term results of percutaneous ethanol injection. Radiology 197:101–108
Livraghi T, Goldberg SN, Lazzaroni S, Meloni F, Solbiati L, Gazelle GS (1999) Small hepatocellular carcinoma: treatment with radio-frequency ablation versus ethanol injection. Radiology 210:655–661
Matsumoto R, Oshio K, Jolesz FA (1992) Monitoring of laser and freezing-induced ablation in the liver with T1-weighted MR imaging. J Magn Reson Imaging 2:555–562
Pacella CM, Bizarri G, Anelli V (1997) Treatment of small hepatocellular carcinoma: value of percutaneous laser interstitial photocoagulation. Radiology 205 (P):200
Rossi S, Fornari F, Buscarini L (1993) Percutaneous ultrasound-guided radiofrequency electrocautery for the treatment of small hepatocellular carcinoma. J Interv Radiol 8:97–103
Rossi S, Di Stasi M, Buscarini E et al (1996) Percutaneous RF interstitial thermal ablation in the treatment of hepatic cancer. AJR Am J Roentgenol 167:759–768
Sironi S, Livraghi T, DelMaschio A (1991) Small hepatocellular carcinoma treated with percutaneous ethanol injection: MR imaging findings. Radiology 180:333–336
Sironi S, Livraghi T, Angeli E et al (1993) Small hepatocellular carcinoma: MR follow-up of treatment with percutaneous ethanol injection. Radiology 187:119–123
Solbiati L, Goldberg SN, Ierace T et al (1997) Hepatic metastases: percutaneous radio-frequency ablation with cooledtip electrodes. Radiology 205:367–373
Vogl TJ, Mack MG, Straub R, Roggan A, Felix R (1997) Percutaneous MRI-guided laser-induced thermotherapy for hepatic metastases for colorectal cancer. Lancet 350:29
Vogl TJ, Mack MG, Roggan A et al (1998) Internally cooled power laser for MR-guided interstitial laser-induced thermotherapy of liver lesions: initial clinical results. Radiology 209:381–385
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Eichler, K., Mack, M.G., Vogl, T.J. (2008). LITT-HCC. In: Vogl, T.J., Helmberger, T.K., Mack, M.G., Reiser, M.F. (eds) Percutaneous Tumor Ablation in Medical Radiology. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-68250-9_15
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DOI: https://doi.org/10.1007/978-3-540-68250-9_15
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