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Procedural Treatments: Laser Trabeculoplasty

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Pearls of Glaucoma Management

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Abstract

There are two main considerations for using laser trabeculoplasty (LTP) vs. medications as a first line or replace­ment treatment. The first is disease related and the second is economic. Disease related issues are efficacy, compliance, diurnal IOP control, and side effects/risks. Economic issues are divided into personal financial impact for the individual patient and medical costs for society in general.

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References

  1. The Glaucoma Laser Trial Research Group. The Glaucoma Laser Trial (GLT) and glaucoma laser trial follow-up study, seven-year results. Am J Ophthalmol 1995;120:718–731.

    Google Scholar 

  2. The Glaucoma Laser Trial Research Group. The Glaucoma Laser Trial (GLT). 2. Results of argon laser trabeculoplasty versus topical medicines. Ophthalmology 1990;97:1403–1413.

    Google Scholar 

  3. Kramer TR and Noecker RJ. Comparison of the morphologic changes after selective laser trabeculoplasty and argon laser trabeculoplasty in human eye bank eyes. Ophthalmology 2001;108:773–779.

    Article  PubMed  CAS  Google Scholar 

  4. Rodrigues MM, Spaeth GL, Donohoo P. Electron microscopy of argon laser therapy in phakic open-angle glaucoma. Ophthalmology 1982;89:198–210.

    PubMed  CAS  Google Scholar 

  5. Latina MA, Park C. Selective targeting of trabecular meshwork cells: in vitro studies of pulsed and CW laser interactions. Exp Eye Res 1995;60:359–371.

    Article  PubMed  CAS  Google Scholar 

  6. Barkana Y, Belkin M. Selective laser trabeculoplasty. Surv Ophthalmol 2007;52:634–654.

    Article  PubMed  Google Scholar 

  7. Damji KF, Shah KC, Rock WJ et al Selective laser trabeculoplasty vs. argon laser trabeculoplasty: a prospective randomized clinical trial. Br J Ophthalmol 1999;83(6):718–722.

    Article  PubMed  CAS  Google Scholar 

  8. Damji KF, Bovell AM, Hodge WG et al. Selective laser trabeculoplasty versus argon laser trabeculoplasty: results from a 1-year randomized clinical trial. Br J Ophthalmol 2006;90:1490–1494.

    Article  PubMed  CAS  Google Scholar 

  9. Juzych MS, Chopra V, Banitt MR et al. Comparison of long-term outcomes of selective laser trabeculoplasty versus argon laser trabeculoplasty in open angle glaucoma. Ophthalmology 2004;111:1853–1859.

    Article  PubMed  Google Scholar 

  10. Latina MA, Sibayan SA, Shin DH et al. Q-switched 532 nm Nd:YAG laser trabeculoplasty (selective laser trabeculoplasty): a multi-center, pilot, clinical study. Ophthalmology 1998;105:2082–2090.

    Article  PubMed  CAS  Google Scholar 

  11. Nagar M, Ogunyomade A, O’Brart DP et al. A randomized, prospective study comparing selective laser trabeculoplasty with latanoprost for the control of intraocular pressure in ocular hypertension and open angle glaucoma. Br J Ophthalmol 2005;89:1413–1417.

    Article  PubMed  CAS  Google Scholar 

  12. Melamed S, Simon B, Levkovitz-Verbin H. Selective laser trabeculoplasty as primary treatment for open-angle glaucoma: a prospective, non-randomized pilot study. Arch Ophthalmol 2003;121:957–960.

    Article  PubMed  Google Scholar 

  13. McIlraith I, Strasfeld M, Colev G et al. Selective laser trabeculoplasty as initial and adjunctive treatment for open angle glaucoma. J Glaucoma 2006;15:124–130.

    Article  PubMed  Google Scholar 

  14. .Katz LJ, Steinmann WC, Marcellino G and the SLT/MED Study Group. Presented at the American Academy of Ophthalmology annual meeting. November, 2006.

    Google Scholar 

  15. Francis BA, Ianchulev T, Schofield JK, Minckler DS. Selective laser trabeculoplasty as a replacement for medical therapy in open angle glaucoma. Am J Ophthalmol 2005;140(3):524–525.

    Article  PubMed  Google Scholar 

  16. Nordstrom BL, Friedman DS, Mozaffari E et al. Persistence and adherence with topical glaucoma therapy. Am J Ophthal­mol 2005;140:598–606.

    Google Scholar 

  17. Kass MA, Meltzer DW, Gordon M, Cooper D, Goldberg J. Compliance with topical pilocarpine treatment. Am J Oph­thalmol 1986;101:515–523.

    CAS  Google Scholar 

  18. Greenidge KC, Spaeth GL, Fiol-Silva Z. Effect of argon laser trabeculoplasty on the glaucomatous diurnal curve. Ophthalmology 1983;90:800–804.

    PubMed  CAS  Google Scholar 

  19. Lee AC, Mosaed S, Weinreb RN, Kripke DF, Liu JH. Effect of laser trabeculoplasty on nocturnal intraocular pressure in medically treated glaucoma patients. Ophthalmology 2007;114:666–670.

    Article  PubMed  Google Scholar 

  20. Buys YM. Economics of selective laser trabeculoplasty as primary therapy for glaucoma. Can J Ophthalmol 2006;41:419–420.

    PubMed  Google Scholar 

  21. Lee R, Hutnik CM. Projected cost comparison of selective laser trabeculoplasty versus glaucoma medication in the Ontario Health Insurance Plan. Can J Ophthalmol 2006;41:449–456.

    PubMed  Google Scholar 

  22. Kramer TR, Noecker R. Comparison of the morphologic changes after selective laser trabeculoplasty and argon laser trabeculoplasty in human eye bank eyes. Ophthalmology 2001;108:773–779.

    Article  PubMed  CAS  Google Scholar 

  23. Simon G, Lowery JA. Comparison of three types of lasers in laser trabeculoplasty in human donor eyes and clinical study. Abstract presented at 2007 ASCRS Symposium, San Diego, USA.

    Google Scholar 

  24. Grayson DK, Camras CB, Podos SM, Lustgarten JS. Long-term reduction of intraocular pressure after repeat argon laser trabeculoplasty. Am J Ophthalmol 1988;106:312–321.

    Article  PubMed  CAS  Google Scholar 

  25. Richter CU, Shingleton BJ, Bellows AR et al. Retreatment with argon laser trabeculoplasty. Ophthalmology 1987;94:1085–1089.

    PubMed  CAS  Google Scholar 

  26. Feldman RM, Katz LJ, Spaeth GL et al. Long-term efficacy of repeat argon laser trabeculoplasty. Ophthalmology 1991;98:1061–1065.

    PubMed  CAS  Google Scholar 

  27. Melamed S, Pei J, Epstein DL. Short term effect of argon laser trabeculoplasty in monkeys. Arch Ophthalmol 1985;103:1546–1552.

    Article  PubMed  CAS  Google Scholar 

  28. Bradley JM, Anderssohn AM, Colvis CM et al. Mediation of laser trabeculoplasty-induced matrix metalloproteinase expression by IL-1beta and TNF-alpha. Invest Ophthalmol Vis Sci 2000;41:422–430.

    PubMed  CAS  Google Scholar 

  29. Alvarado JA, Alvarado RG, Yeh RF, Franse-Carman L, Marcellino GR, Brownstein MJ. A new insight into the cellular regulation of aqueous outflow: how trabecular meshwork endothelial cells drive a mechanism that regulates the permeability of Schlemm’s canal endothelial cells. Br J Ophthalmol 2005;89:1500–1505.

    Article  PubMed  CAS  Google Scholar 

  30. Bylsma SS, Samples JR, Acott TS, Van Buskirk EM. Trabecular cell division after argon laser trabeculoplasty. Arch Ophthalmol 1988;106:544–547.

    Article  PubMed  CAS  Google Scholar 

  31. Acott TS, Samples JR, Bradley JM et al. Trabecular repopulation by anterior trabecular meshwork cells after laser trabeculoplasty. Am J Ophthalmol 1989;107:1–6.

    PubMed  CAS  Google Scholar 

  32. Bylsma SS, Samples JR, Acott TS et al. DNA replication in the cat trabecular meshwork after argon laser trabeculoplasty in vivo. J Glaucoma 1994;3:36–43.

    Article  PubMed  CAS  Google Scholar 

  33. Dueker DK, Norberg M, Johnson DH et al. Stimulation of cell division by argon and Nd:YAG laser trabeculoplasty in cynomolgus monkeys. Invest Ophthalmol Vis Sci 1990;31:115–124.

    PubMed  CAS  Google Scholar 

  34. Fea AM, Bosone A, Rolle T et al. Micropulsed laser trabeculoplasty: a pilot study. Presented at 2007 International Glaucoma Symposium, Athens, Greece and 2007 World Glaucoma Congress, Singapore.

    Google Scholar 

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Authors and Affiliations

  1. Doheny Eye Institute, Keck School of Medicine, University of Southern California, 1450 San Pablo Street, DEI 4804, Los Angeles, CA, 90033, USA

    Brian A. Francis

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  1. Brian A. Francis
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Correspondence to Brian A. Francis .

Editor information

Editors and Affiliations

  1. Jules Stein Eye Institute, Stein Plaza 100, Los Angeles, 90095, U.S.A.

    JoAnn A. Giaconi

  2. Jules Stein Eye Institute, Stein Plaza 100, Los Angeles, 90095, U.S.A.

    Simon K. Law

  3. Jules Stein Eye Institute, Stein Plaza 100, Los Angeles, 90095, U.S.A.

    Anne L. Coleman

  4. Jules Stein Eye Institute, Stein Plaza 100, Los Angeles, 90095, U.S.A.

    Joseph Caprioli

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Francis, B.A. (2010). Procedural Treatments: Laser Trabeculoplasty. In: Giaconi, J., Law, S., Coleman, A., Caprioli, J. (eds) Pearls of Glaucoma Management. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-68240-0_32

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  • DOI: https://doi.org/10.1007/978-3-540-68240-0_32

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-68238-7

  • Online ISBN: 978-3-540-68240-0

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