Liver cirrhosis is the final stage of a chronic hepatopathy characterized by widespread fibrosis, nodule formation and destruction of the lobular and vascular architecture of the liver. Alcohol abuse and chronic viral hepatitis are the main causes of liver cirrhosis. Other less frequent causes are inherited (e.g., hemochromatosis, Wilson’s disease, α1-antitrypsin deficiency) and autoimmune disorders (e.g., autoimmune hepatitis, primary biliary cirrhosis, primary sclerosing cholangitis) and vascular liver diseases. Any cirrhosis of the liver irrespective of its origin represents a risk factor for developing hepatocellular carcinoma, the most frequent primary malignancy of the liver. The following chapter provides an overview of the most frequent hepatopathies causing cirrhosis of the liver.
KeywordsBone Mineral Density Chronic Hepatitis Transplant Recipient Primary Biliary Cirrhosis Primary Sclerosing Cholangitis
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