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Predisposing Diseases

  • Gerald U. Denk
  • Ulrich Beuers
  • Johannes R. Bogner
  • Michael Fischereder
Part of the Medical Radiology book series (MEDRAD)

Abstract

Liver cirrhosis is the final stage of a chronic hepatopathy characterized by widespread fibrosis, nodule formation and destruction of the lobular and vascular architecture of the liver. Alcohol abuse and chronic viral hepatitis are the main causes of liver cirrhosis. Other less frequent causes are inherited (e.g., hemochromatosis, Wilson’s disease, α1-antitrypsin deficiency) and autoimmune disorders (e.g., autoimmune hepatitis, primary biliary cirrhosis, primary sclerosing cholangitis) and vascular liver diseases. Any cirrhosis of the liver irrespective of its origin represents a risk factor for developing hepatocellular carcinoma, the most frequent primary malignancy of the liver. The following chapter provides an overview of the most frequent hepatopathies causing cirrhosis of the liver.

Keywords

Bone Mineral Density Chronic Hepatitis Transplant Recipient Primary Biliary Cirrhosis Primary Sclerosing Cholangitis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2008

Authors and Affiliations

  • Gerald U. Denk
    • 1
  • Ulrich Beuers
    • 2
  • Johannes R. Bogner
    • 3
  • Michael Fischereder
    • 3
  1. 1.Department of Medicine II, University Hospitals — GrosshadernLudwig-Maximilians-University of MunichMunichGermany
  2. 2.Department of Gastroenterology and Hepatology, Academic Medical CenterUniversity of AmsterdamAmsterdamThe Netherlands
  3. 3.Medical Policlinic, University Hospitals — InnenstadtLudwig- Maximilians-University of MunichMunichGermany

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