• Andrea Baur-Melnyk
  • Holger Boehm
Part of the Medical Radiology book series (MEDRAD)


Osteoporosis is defined as a progressive systemic skeletal disease characterized by diminishing bone mass and deterioration of the microarchitecture of bone tissue, resulting in a loss of mechanical strength and susceptibility to fracture. Typical fractures associated with osteoporosis (fragility fractures) are found in the spine, hip and wrist. Osteoporosis can be classified as primary or secondary. According to the time of manifestation primary Osteoporosis is termed as juvenile, post-menopausal or senile. A wide spectrum of causes may lead to secondary osteoporosis. The most common conditions include osteoporosis due to drugs (e.g. corticoids, phenytoin) renal or hepatic insufficiency, hyperparathyreoidism, hyperthyroidism, metastases or hematologic bone marrow neoplasia.


Bone Mineral Density Vertebral Fracture Trabecular Bone Osteoporotic Fracture Fragility Fracture 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2008

Authors and Affiliations

  • Andrea Baur-Melnyk
    • 1
  • Holger Boehm
    • 1
  1. 1.Department of Clinical Radiology, University Hospitals — GrosshadernLudwig-Maximilians-University of MunichMunichGermany

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