Advertisement

Glutamine-phenylpyruvate transaminase

Part of the Springer Handbook of Enzymes book series (HDBKENZYMES, volume 35)

Nomenclature

EC number

2.6.1.64

Systematic name

L-glutamine:phenylpyruvate aminotransferase

Recommended name

glutamine-phenylpyruvate transaminase

Synonyms

EC 2.6.1.14 lt;6gt; (lt;6gt; maybe identical [11]) [11]

EC 2.6.1.15 lt;1, 6gt; (lt;6gt; identical with [16]) [7, 16]

EC 2.6.1.7 lt;6gt; (lt;6gt; maybe identical [11]) [11]

GTK lt;6gt; [13, 161

KAT/GTK lt;6gt; [11, 16]

cysteine conjugate β-lyase/glutamine transaminase K lt;6gt; [14]

glutamine transaminase K lt;2, 3, 6gt; [1, 5, 6, 9, 12, 13, 15]

glutamine transaminase L lt;6gt; [1, 5, 6]

glutamine-phenylpyruvate aminotransferase

histidine pyruvate aminotransferase isoenzyme 2 lt;6gt; [4]

kynurenine aminotransferase/glutamine transaminase K lt;6gt; [11, 16]

CAS registry number

68518-06-9

Keywords

Isonicotinic Acid Ammonium Sulfate Solution Isonicotinic Acid Hydrazide Gallus Domesticus Cysteine Conjugate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. [1]
    Cooper, A.J.L.; Meister, A.: Isolation and properties of a new glutamine transaminase from rat kidney. J. Biol. Chem., 249, 2554–2561 (1974)PubMedGoogle Scholar
  2. [2]
    Van Leuven, F.: Highly purified glutamine transaminase from rat brain. Physical and kinetic properties. Eur. J. Biochem., 58, 153–158 (1975)PubMedCrossRefGoogle Scholar
  3. [3]
    Van Leuven, F.: Glutamine transaminase from brain tissue. Further studies on kinetic properties and specificity of the enzyme. Eur. J. Biochem., 65, 271–274 (1976)PubMedCrossRefGoogle Scholar
  4. [4]
    Noguchi, T.; Okuno, E.; Kido, R.: Identity of rat kidney histidine-pyruvate aminotransferase with glutamine-oxo acid aminotransferase. Biochem. J., 161, 177–179 (1977)PubMedGoogle Scholar
  5. [5]
    Cooper, A.J.L.: Purification of soluble and mitochondrial glutamine transaminase K from rat kidney. Use of a sensitive assay involving transamination between l-phenylalanine and α-keto-γ-methiolbutyrate. Anal. Biochem., 89, 451–460 (1978)PubMedCrossRefGoogle Scholar
  6. [6]
    Cooper, A.J.L.; Meister, A.: Glutamine transaminase K from rat kidney. Methods Enzymol., 113, 344–349 (1985)PubMedCrossRefGoogle Scholar
  7. [7]
    Ricci, G.; Nardini, M.; Federici, G.; Cavallini, D.: The transamination of l-cystathionine, l-cystine and related compounds by a bovine kidney transaminase. Eur. J. Biochem., 157, 57–63 (1986)PubMedCrossRefGoogle Scholar
  8. [8]
    Wu, G.; Thompson, J.R.; Baracos, V.E.: Glutamine metabolism in skeletal muscles from the broiler chick (Gallus domesticus) and the laboratory rat (Rattus norvegicus). Biochem. J., 274, 769–774 (1991)PubMedGoogle Scholar
  9. [9]
    Makar, T.K.; Nedergaard, M.; Preuss, A.; Hertz, L.; Cooper, A.J.: Glutamine transaminase K and ω-amidase activities in primary cultures of astrocytes and neurons and in embryonic chick forebrain: Marked induction of brain glutamine transaminase K at time of hatching. J. Neurochem., 62, 1983–1988 (1994)PubMedCrossRefGoogle Scholar
  10. [10]
    Abraham, D.G.; Thomas, R.J.; Cooper, A.J.: Glutamine transaminase K is not a major cysteine S-conjugate β-lyase of rat kidney mitochondria: evidence that a high-molecular weight enzyme fulfills this role. Mol. Pharmacol., 48, 855–860 (1995)PubMedGoogle Scholar
  11. [11]
    Malherbe, P.; Alberati-Giani, D.; Koehler, C.; Cesura, A.M.: Identification of a mitochondrial form of kynurenine aminotransferase/glutamine transaminase K from rat brain. FEBS Lett., 367, 141–144 (1995)PubMedCrossRefGoogle Scholar
  12. [12]
    Abraham, D.G.; Cooper, A.J.: Cloning and expression of a rat kidney cytosolic glutamine transaminase K that has strong sequence homology to kynurenine pyruvate aminotransferase. Arch. Biochem. Biophys., 335, 311–320 (1996)PubMedCrossRefGoogle Scholar
  13. [13]
    Trevisan, A.; Cristofori, P.; Fanelli, G.; Bicciato, F.; Stocco, E.: Glutamine transaminase K intranephron localization in rats determined by urinary excretion after treatment with segment-specific nephrotoxicants. Arch. Toxicol., 72, 531–535 (1998)PubMedCrossRefGoogle Scholar
  14. [14]
    Commandeur, J.N.; Andreadou, I.; Rooseboom, M.; Out, M.; de Leur, L.J.; Groot, E.; Vermeulen, N.P.: Bioactivation of selenocysteine Se-conjugates by a highly purified rat renal cysteine conjugate β-lyase/glutamine transaminase K. J. Pharmacol. Exp. Ther., 294, 753–761 (2000)PubMedGoogle Scholar
  15. [15]
    Han, Q.; Fang, J.; Li, J.: Kynurenine aminotransferase and glutamine transaminase K of Escherichia coli: identity with aspartate aminotransferase. Biochem. J., 360, 617–623 (2001)PubMedCrossRefGoogle Scholar
  16. [16]
    Mosca, M.; Croci, C.; Mostardini, M.; Breton, J.; Malyszko, J.; Avanzi, N.; Toma, S.; Benatti, L.; Gatti, S.: Tissue expression and translational control of rat kynurenine aminotransferase/glutamine transaminase K mRNAs. Biochim. Biophys. Acta, 1628, 1–10 (2003)PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2007

Personalised recommendations