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Galactokinase

Part of the Springer Handbook of Enzymes book series (HDBKENZYMES, volume 35)

Nomenclature

EC number

2.7.1.6

Systematic name

ATP:d-galactose 1-phosphotransferase

Recommended name

galactokinase

Synonyms

ATP:d-galactose-1-phosphotransferase

GALK

Gal1p

galactose kinase

kinase, galacto- (phosphorylating)

CAS registry number

9030-53-9

Keywords

Ammonium Sulfate Cataract Formation Bifidobacterium Bifidum Leloir Pathway Tetrahymena Thermophila 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. [1]
    Neufeld, E.F.; Feingold, D.S.; Hassid, W.Z.: Phosphorylation of d-galactose and l-arabinose by extracts from Phaseolus aureus seedlings. J. Biol. Chem., 235, 906–909 (1960)PubMedGoogle Scholar
  2. [2]
    Vorgias, C.E.; Lemaire, H.G.; Wilson, K.S.: Overexpression and purification of the galactose operon enzymes from Escherichia coli. Protein Expr. Purif., 2, 330–338 (1991)PubMedCrossRefGoogle Scholar
  3. [3]
    Szumilo, T.: A galactokinase of Mycobacterium sp. 279 galactose mutant. Acta Microbiol. Pol., 31, 249–256 (1982)PubMedGoogle Scholar
  4. [4]
    Talbot, B.; Thirion, J.P.: Isolation, purification and partial characterization of galactokinase from Chinese hamster liver. Int. J. Biochem., 14, 719–726 (1982)PubMedCrossRefGoogle Scholar
  5. [5]
    Wilson, D.B.; Schell, M.A.: Galactokinase from Saccharomyces cerevisiae. Methods Enzymol., 90, 30–35 (1982)PubMedGoogle Scholar
  6. [6]
    Ballard, F.J.: Galactokinase from pig liver. Methods Enzymol., 42C, 43–47 (1975)CrossRefGoogle Scholar
  7. [7]
    Blume, K.G.; Beutler, E.: Galactokinase from human erythrocytes. Methods Enzymol., 42C, 47–53 (1975)Google Scholar
  8. [8]
    Dey, P.M.: Galactokinase of Vicia faba seeds. Eur. J. Biochem., 136, 155–159 (1983)PubMedCrossRefGoogle Scholar
  9. [9]
    Blume, K.G.; Beutler, E.: Purification and properties of galactokinase from human red blood cells. J. Biol. Chem., 246, 6507–6510 (1971)PubMedGoogle Scholar
  10. [10]
    Schell, M.A.; Wilson, D.B.: Purification and properties of galactokinase from Saccharomyces cerevisiae. J. Biol. Chem., 252, 1162–1166 (1977)PubMedGoogle Scholar
  11. [11]
    Stambolian, D.; Scarpino-Myers, V.; Harris, H.: Purification of human galactokinase and evidence for its existence as a monomer form. Biochim. Biophys. Acta, 831, 306–312 (1985)PubMedGoogle Scholar
  12. [12]
    Lee, L.J.; Kinoshita, S.; Kumagai, H.; Tochikura, T.: Galactokinase of Bifidobacterium bifidum. Agric. Biol. Chem., 44, 2961–2966 (1980)Google Scholar
  13. [13]
    Lavine, J.E.; Cantlay, E.; Roberts, C.T.; Morse, D.E.: Purification and properties of galactokinase from Tetrahymena thermophila. Biochim. Biophys. Acta, 717, 76–85 (1982)PubMedGoogle Scholar
  14. [14]
    Schlesinger, D.H.; Schell, M.A.; Wilson, D.B.: The NH2-terminal sequences of galactokinase from Escherichia coli and Saccharomyces cerevisiae. FEBS Lett., 83, 45–47 (1977)PubMedCrossRefGoogle Scholar
  15. [15]
    Lee, L.; Kimura, A.; Tochikura, T.: Purification and properties of galactokinase from Bifidobacterium bifidum. J. Ferment. Technol., 55, 19–26 (1977)Google Scholar
  16. [16]
    Srivastava, S.K.; Blume, K.-G.; Van Loon, C.; Beutler, E.: Purification and kinetic properties of galactokinase from human placenta. Arch. Biochem. Biophys., 150, 191–198 (1972)CrossRefGoogle Scholar
  17. [17]
    Chan, P.H.; Hassid, W.Z.: One step purification of d-galactose and l-arabinose kinases from Phaseolus aureus seedlings by ATP-sepharose affinity chromatography. Anal. Biochem., 64, 372–379 (1975)PubMedCrossRefGoogle Scholar
  18. [18]
    Asada, M.; Okano, Y.; Imamura, T.; Suyama, I.; Hase, Y.; Isshiki, G.: Molecular characterization of galactokinase deficiency in Japanese patients. J. Hum. Genet., 44, 377–382 (1999)PubMedCrossRefGoogle Scholar
  19. [19]
    Ai, Y.; Jenkins, N.A.; Copeland, N.G.; Gilbert, D.H.; Bergsma, D.J.; Stambolian, D.: Mouse galactokinase: isolation, characterization, and location on chromosome 11. Genome Res., 5, 53–59 (1995)PubMedCrossRefGoogle Scholar
  20. [20]
    Yang, J.; Fu, X.; Jia, Q.; Shen, J.; Biggins, J.B.; Jiang, J.; Zhao, J.; Schmidt, J.J.; Wang, P.G.; Thorson, J.S.: Studies on the substrate specificity of Escherichia coli galactokinase. Org. Lett., 5, 2223–2226 (2003)PubMedCrossRefGoogle Scholar
  21. [21]
    Thoden, J.B.; Holden, H.M.: Molecular structure of galactokinase. J. Biol. Chem., 278, 33305–33311 (2003)PubMedCrossRefGoogle Scholar
  22. [22]
    De Geus, D.; Hartley, A.P.; Sedelnikova, S.E.; Glynn, S.E.; Baker, P.J.; Verhees, C.H.; Van Der Oost, J.; Rice, D.W.: Cloning, purification, crystallization and preliminary crystallographic analysis of galactokinase from Pyrococcus furiosus. Acta Crystallogr. Sect. D, 59, 1819–1821 (2003)CrossRefGoogle Scholar
  23. [23]
    Okano, Y.; Asada, M.; Fujimoto, A.; Ohtake, A.; Murayama, K.; Hsiao, K.J.; Choeh, K.; Yang, Y.; Cao, Q.; Reichardt, J.K.; Niihira, S.; Imamura, T.; Yamano, T.: A genetic factor for age-related cataract: identification and characterization of a novel galactokinase variant, Osaka, in asians. Am. J. Hum. Genet., 68, 1036–1042 (2001)PubMedCrossRefGoogle Scholar
  24. [24]
    Zenke, F.T.; Engels, R.; Vollenbroich, V.; Meyer, J.; Hollenberg, C.P.; Breunig, K.D.: Activation of Ga14p by galactose-dependent interaction of galactokinase and Ga180p. Science, 272, 1662–1665 (1996)PubMedCrossRefGoogle Scholar
  25. [25]
    Timson, D.J.; Reece, R.J.: Functional analysis of disease-causing mutations in human galactokinase. Eur. J. Biochem., 270, 1767–1774 (2003)PubMedCrossRefGoogle Scholar

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© Springer-Verlag Berlin Heidelberg 2007

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