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Aspartate transaminase

  • Chapter
Book cover Class 2 · Transferases VI

Part of the book series: Springer Handbook of Enzymes ((HDBKENZYMES,volume 34))

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Nomenclature

EC number

2.6.1.1

Systematic name

l-aspartate:2-oxoglutarate aminotransferase

Recommended name

aspartate transaminase

Synonyms

2-oxoglutarate-glutamate aminotransferase

AAT

AST

AspAT <1, 3, 7, 12, 35, 37, 39, 42> [8, 54, 55, 59, 60-63, 67, 69]

AspT

GOT <9> [15]

GOT (enzyme)

l-aspartate transaminase

l-aspartate-2-ketoglutarate aminotransferase

l-aspartate-2-oxoglutarate aminotransferase

l-aspartate-2-oxoglutarate-transaminase

l-aspartate-α-ketoglutarate transaminase

l-aspartic aminotransferase

aminotransferase, aspartate

aspartate α-ketoglutarate transaminase

aspartate aminotransferase

aspartate-2-oxoglutarate transaminase

aspartate:2-oxoglutarate aminotransferase

aspartic acid aminotransferase

aspartic aminotransferase

aspartyl aminotransferase

glutamate oxaloacetate transaminase

glutamate-oxaloacetate aminotransferase

glutamate-oxalate transaminase

glutamic-aspartic aminotransferase

glutamic-aspartic transaminase

glutamic-oxalacetic transaminase

glutamic-oxaloacetic transaminase

oxaloacetate transferase

oxaloacetate-aspartate aminotransferase

transaminase A

Additional information <3, 37> (<3,37> aspartate aminotransferases are divided into 2 subgroups: subgroup Ia, inclusive the enzyme of Escherichia coli, possess Arg292 for substrate binding and show a specificity for acidic subtrates only, subgroup Ib, inclusive the enzyme of Thermus thermophilus, can utilize acidic as well as neutral substrates [61]; <3> EC 2.6.1157 may be converted to EC 2.6.1.1 by controlled proteolysis with subtilisin, the 2 enzymes are encoded by 2 different genes with high sequence homology [1]) [1, 61]

CAS registry number

9000-97-9

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    Dietmar Schomburg , Ida Schomburg  & Antje Chang ,  & 

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(2007). Aspartate transaminase. In: Schomburg, D., Schomburg, I., Chang, A. (eds) Class 2 · Transferases VI. Springer Handbook of Enzymes, vol 34. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-49755-4_35

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