Abstract
As the field of nanotechnology advances, many nano-sized materials have been successfully used in drug delivery systems. However, recent practices in offering drugs with long circulation time and efficient targeting, and/or developing new therapeutic strategies are challenging nano-sized drug delivery carriers with more defined biological properties and functionalities. Most nano-sized delivery vehicles and materials currently being used cannot completely fulfill these requirements. To address these issues, syntheses of new carrier materials and modification of existing nano-sized materials with tunable properties are considered to be two effective strategies thus far. In this review article, we will focus on the latter. It is thought that through modification one can control and tailor the properties of nano-sized materials in a predictable manner, as well as provide them with precise properties and functionalities. These modifications can bring new and unique capabilities to many drug delivery systems. Recent progress on drug delivery applications for modified and functionalized nano-sized materials will be highlighted, after the methods used to modify nano-sized materials are discussed briefly.
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© 2009 Tsinghua University Press, Beijing and Springer-Verlag GmbH Berlin Heidelberg
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Xu, T., Nichols, H.L., Zhang, N., Wen, X. (2009). Modification of Nano-sized Materials for Drug Delivery. In: Shi, D. (eds) NanoScience in Biomedicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-49661-8_15
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DOI: https://doi.org/10.1007/978-3-540-49661-8_15
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