Stem Cells and Nanostructured Materials

Beachley, Vince; Wen, Xuejun

doi:10.1007/978-3-540-49661-8_1

Vince Beachley⁴ &
Xuejun Wen^4,5,6

1590 Accesses

Abstract

Stem cells and nanomaterials are currently two of the most promising technologies for tissue regeneration and the treatment of degenerative disease. Because of their ability to self-renew and differentiate into any cell type, stem cells offer the potential to regrow all types of damaged or degenerated tissues that are unrepairable by currently available treatment methods. Nanomaterials may prove to be ideal growth substrates for tissue regeneration as well as an ideal delivery vehicle for the diagnostic markers, growth factors, and drugs that are required to promote tissue regeneration and treat degenerative disease. Despite their great potential, stem cell behaviors such as proliferation and differentiation must be tightly regulated in order for this technology to be practical in a clinical setting. Experimental evidence has shown that the interactions of nanomaterials with stem cells can have a significant effect on many types of stem cell behaviors. In addition, nanomaterials can be used to provide targeted delivery of various agents in a controlled manner that allows for regulation of the chemical environment. Regulation of the chemical environment is critical for controlled guidance of stem cell behavior and for the treatment of degenerative disease. A precise understanding of the interactions between stem cells and nanomaterials is an important step toward unlocking the great potential of these two technologies.

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Authors and Affiliations

Department of Bioengineering, Clemson University, Charleston, SC, 29425, USA
Vince Beachley & Xuejun Wen
Department of Cell Biology and Anatomy, Medical University of South Carolina, Charleston, SC, 29425, USA
Xuejun Wen
Department of Orthopedic Surgery, Medical University of South Carolina, Charleston, SC, 29425, USA
Xuejun Wen

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Vince Beachley
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Correspondence to Xuejun Wen .

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Editors and Affiliations

Department of Chemical and Materials Engineering, College of Engineering, University of Cincinnati, Cincinnati, OH, 45221, USA
Donglu Shi
The Institute for Advanced Materials and Nano Biomedicine, Tongji University, Shanghai, 200092, China
Donglu Shi
Research Institute of Micro/Nano Science and Technology, Shanghai Jiao Tong University, Shanghai, 200240, China
Donglu Shi

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Beachley, V., Wen, X. (2009). Stem Cells and Nanostructured Materials. In: Shi, D. (eds) NanoScience in Biomedicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-49661-8_1

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DOI: https://doi.org/10.1007/978-3-540-49661-8_1
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-49660-1
Online ISBN: 978-3-540-49661-8
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