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Intensive Care Medicine pp 398–406Cite as

The Role of Protective Ventilation in Cardiac Surgery Patients

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Part of the book series: Yearbook of Intensive Care and Emergency Medicine ((YEARBOOK,volume 2007))

Abstract

Cardiac surgery is associated with a pulmonary and systemic inflammatory response. The pulmonary effects of this inflammatory reaction are often modest: decreased lung compliance, pulmonary edema, increased intrapulmonary shunt fraction and decreased functional residual capacity (FRC) [1]. Less than 2% of patients undergoing cardiac surgery develop full blown respiratory failure, the acute respiratory distress syndrome (ARDS) [1]. For example, after cardiac surgery, FRC is reduced up to 40–50% during the first 24 hours after extubation [2]. However, after general anesthesia, FRC is only decreased by 20–30% [3]. This exaggerated disturbance of pulmonary function is not yet fully understood. It has been suggested that this impaired pulmonary function is the result of pulmonary inflammation, triggered by cardiopulmonary bypass (CPB), ischemia-reperfusion injury, the surgical procedure itself, or by mechanical ventilation.

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Authors and Affiliations

  1. Department of Intensive Care, Erasmus University Medical Center, room H-602, PO Box 2040, 3000 CA, Rotterdam, Netherlands

    D. Gommers & D. dos Reis Miranda

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  1. D. Gommers
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  2. D. dos Reis Miranda
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© 2007 Springer Science + Business Media Inc.

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Gommers, D., dos Reis Miranda, D. (2007). The Role of Protective Ventilation in Cardiac Surgery Patients. In: Intensive Care Medicine. Yearbook of Intensive Care and Emergency Medicine, vol 2007. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-49433-1_36

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  • DOI: https://doi.org/10.1007/978-3-540-49433-1_36

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-49432-4

  • Online ISBN: 978-3-540-49433-1

  • eBook Packages: MedicineMedicine (R0)

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