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MAP Kinase Cascades in Arabidopsis: Their Roles in Stress and Hormone Responses

  • Tsuyoshi Mizoguchi
  • Kazuya Ichimura
  • Riichiro Yoshida
  • Kazuo Shinozaki
Part of the Results and Problems in Cell Differentiation book series (RESULTS, volume 27)

Summary

Mitogen-activated protein kinase (MAPK) cascades have essen­tial roles in diverse intracellular signaling processes in plants, animals and yeasts. In plants, MAPK and MAPK-like kinase activities are transiently ac­tivated in response to environmental stresses and plant hormones. In addi­tion, transcription of genes encoding protein kinases involved in MAPK cascades is upregulated by environmental stresses. A possible MAPK cas­cade of Arabidopsis was identified based on both the yeast two-hybrid anal­ysis and functional complementation analysis of yeast mutants. This MAPK cascade may have important roles in stress signal transduction pathways in Arabidopsis.

Keywords

Histidine Kinase MAPK Cascade Plant Signal Transduction Stress Signal Transduction Pathway Gene Encode Protein Kinase 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Banno H, Hirano K, Nakamura T, Irie K, Nomoto S, Matsumoto K, Machida Y (1993) NPK1, a tobacco gene that encodes a protein with a domain homologous to yeast BCK1, STE11 and Byr2 protein kinases. Mol Cell Biol 13 :4745–4752PubMedGoogle Scholar
  2. Bögre L, Ligterink W, Heberle-Bors E, Hirt H (1996a) Mechanosensors in plants. Nature 383: 489–490PubMedCrossRefGoogle Scholar
  3. Bögre L, Ligterink W, Meskience I, Barker PJ, Heberle-Bors E, Huskisson NS, Hirt H (1996b) Wounding induces the rapid and transient activation of a specific MAP kinase pathway. Plant Cell 9:75–83Google Scholar
  4. Brewster JL, de Valoir T, Dwyer ND, Winter E, Gustin MC (1993) An osmosensing signal transduction pathway in yeast. Science 259 : 1760–1763PubMedCrossRefGoogle Scholar
  5. Cano E, Mahadevan LC (1995) Parallel signal processing among mammalian MAPKs.TIBS 20: 117–122Google Scholar
  6. Chang C, Kwok SF, Bleecker AB, Meyerowitz EM (1993) Arabidopsis ethylene-response gene ETR1: similarity of product to two-component regulators. Science 262 : 539–544PubMedCrossRefGoogle Scholar
  7. Clark KL, Larsen PB, Wang X, Chang C (1998) Association of the Arabidopsis CTR1 Raf-like kinase with the ETR1 and ERS ethylene receptors. Proc Natl Acad Sci USA 95 : 5401–5406PubMedCrossRefGoogle Scholar
  8. Herskowitz I (1995) MAP kinase pathways in yeast: for mating and more. Cell 80: 187–197PubMedCrossRefGoogle Scholar
  9. Hirt H (1997) Multiple roles of MAP kinases in plant signal transduction. Plant Sci 2 : 11–15Google Scholar
  10. Ichimura K, Mizoguchi T, Hayashida N, Seki M, Shinozaki K (1998a) Molecular cloning and characterization of three cDNAs encoding putative mitogen-activated protein kinase kinases (MAPKKs) in Arabidopsis thaliana. DNA Res 5 : 341–348PubMedCrossRefGoogle Scholar
  11. Ichimura K, Mizoguchi T, Irie K, Morris P, Giraudat J, Matsumoto K, Shinozaki K (1998b) Isolation of ATMEKK1 (a MAP kinase kinase kinase)-interacting proteins and analysis of a MAP kinase cascade in Arabidopsis. Biochem Biophys Res Comm 253 : 532–543PubMedCrossRefGoogle Scholar
  12. Jonak C, Heberle-Bors E, Hirt H (1994) MAP kinases: universal multi-purpose signaling tools. Plant Mol Biol 24 : 407–416PubMedCrossRefGoogle Scholar
  13. Jonak C, Kiegel S, Ligterink W, Barker PJ, Huskisson NS, Hirt H (1996) Stress signaling in plants: a mitogen-activated protein kinase pathway is activated by cold and drought. Proc Natl Acad Sci USA 93 : 11274–11279PubMedCrossRefGoogle Scholar
  14. Kakimoto T (1996) CKI1, a histidine kinase homologue implicated in cytokinin signal transduction. Science 274 : 982–985PubMedCrossRefGoogle Scholar
  15. Kamada Y, Jung US, Piotrowski J, Levin DE (1995) The protein kinase C-activated MAP kinase pathway of Saccharomyces cerevisiae mediates a novel aspect of the heat shock response. Genes Dev 13 : 1559–1571CrossRefGoogle Scholar
  16. Kieber JJ, Rothenberg M, Roman G, Feldmann KA, Ecker JR (1993) CTR1: a negative regulator of the ethylene response pathway in Arabidopsis, encodes a member of the Raf family of protein kinases. Cell 72 : 427–441PubMedCrossRefGoogle Scholar
  17. Ligterink W, Kroj T, Nieden UZ, Hirt H, Scheel D (1997) Receptor-mediated activation of a MAP kinase in pathogen defense of plants. Science 276 : 2054–2057PubMedCrossRefGoogle Scholar
  18. Madhani HD, Fink GR (1998) The riddle of MAP kinase signaling specificity. Trends Genet 14: 151–155PubMedCrossRefGoogle Scholar
  19. Maeda T, Takekawa M, Saito H (1995) Activation of yeast PBS2 MAPKK by MAPKKKs or by binding of an SH3-containing osmosensor. Science 269 : 554–558PubMedCrossRefGoogle Scholar
  20. Miyata S, Urao T, Yamaguchi-Shinozaki K, Shinozaki K (1998) Characterization of genes for twocomponent phosphorelay mediators with a single Hpt domain in Arabidopsis thaliana. FEBS Lett 437 :11–14PubMedCrossRefGoogle Scholar
  21. Mizoguchi T, Hayashida N, Yamaguchi-Shinozaki K, Kamada H, Shinozaki K (1993) ATMPKs: a gene family of plant MAP kinases in Arabidopsis thaliana. FEBS Lett 336 : 440–444PubMedCrossRefGoogle Scholar
  22. Mizoguchi T, Gotoh Y, Nishida E, Yamaguchi-Shinozaki K, Hayashida N, Iwasaki T, Kamada H, Shinozaki K (1994) Characterization of two cDNAs that encode MAP kinase homologues in Arabidopsis thaliana and analysis of the possible role of auxin in activating such kinase activities in cultured cells. Plant J 5 : 111–122PubMedCrossRefGoogle Scholar
  23. Mizoguchi T, Irie K, Hirayama T, Hayashida N, Yamaguchi-Shinozaki K, Matsumoto K, Shinozaki K (1996) A gene encoding a mitogen-activated protein kinase kinase kinase is induced simultaneously with genes for a mitogen-activated protein kinase and an S6 ribosomal protein kinase by touch, cold, and water stress in Arabidopsis thaliana. Proc Natl Acad Sci USA 93: 765–769PubMedCrossRefGoogle Scholar
  24. Mizoguchi T, Ichimura K, Shinozaki K (1997) Environmental stress response in plants: the role of mitogen-activated protein kinases. Trends Biotechnol 15 : 15–19PubMedCrossRefGoogle Scholar
  25. Mizoguchi T, Ichimura K, Irie K, Morris P, Giraudat J, Matsumoto K, Shinozaki K (1998) Identification of a possible MAP kinase cascade in Arabidopsis thaliana based on pairwise yeast two-hybrid analysis and functional complementation tests of yeast mutants. FEBS Lett 437 : 56–60PubMedCrossRefGoogle Scholar
  26. Morris PC, Guerrier D, Leung J, Giraudat J (1997) Cloning and characterization of MEK1, an Arabidopsis gene encoding a homologue of MAP kinase kinase. Plant Mol Biol 35 :1057–1064PubMedCrossRefGoogle Scholar
  27. Nishida E, Gotoh Y (1993) The MAP kinase cascade is essential for diverse signal transduction pathways. TIBS 18 :128–131PubMedGoogle Scholar
  28. Nishihama R, Banno H, Shibata W, Hirano K, Nakashima M, Usami S, Machida Y (1995) Plant homologues of components of MAPK (mitogen-activated protein kinase) signal pathways in yeast and animal cells. Plant Cell Physiol 36 : 749–757PubMedGoogle Scholar
  29. Nishihama R, Banno H, Kawahara E, Irie K, Machida Y (1997) Possible involvement of differential splicing in regulation of the activity of Arabidopsis ANP1 that is related to mitogen-activated protein kinase kinase kinases (MAPKKKs). Plant J 12 : 39–48PubMedCrossRefGoogle Scholar
  30. Posas F, Wurgler-Murphy SM, Maeda T, Witten EA, Thai TC, Saito H (1996) Yeast HOG1 MAP kinase cascade is regulated by a multistep phosphorelay mechanism in the SLN1-YPD1-SSK1 “two-component” osmosensor. Cell 86 : 865–875PubMedCrossRefGoogle Scholar
  31. Posas F, Saito H (1997) Osmotic activation of the HOG MAPK pathway via Stel lp MAPKKK: scaffold role of Pbs2p MAPKK. Science 276 :1702–1705PubMedCrossRefGoogle Scholar
  32. Raingeaud J, Whitmarsh AJ, Barret T, Dérijard B, Davis RJ (1996) MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway. Mol Cell Biol 16: 1247–1255PubMedGoogle Scholar
  33. Seo S, Okamoto M, Seto H, Ishizuka K, Sano H, Ohashi Y (1995) Tobacco MAP kinase: a possible mediator in wound signal transduction pathways. Science 270 :1988–1992PubMedCrossRefGoogle Scholar
  34. Shibata W, Banno H, Ito Y, Hirano K, Irie K, Usami S, Machida C, Machida Y (1995) A tobacco protein kinase, NPK2, has a domain homologous to a domain found in activators of mitogenactivated protein kinases (MAPKKs). Mol Gen Genet 246 : 401–410PubMedCrossRefGoogle Scholar
  35. Shinozaki K, Yamaguchi-Shinozaki K (1997) Gene expression and signal transduction in waterstress response. Plant Physiol 115 : 327–334PubMedCrossRefGoogle Scholar
  36. Urao T, Yakubov B, Yamaguchi-Shinozaki K, Shinozaki K (1998) Stress-responsive expression of genes for two-component response regulator-like proteins in Arabidopsis thaliana. FEBS Lett 427:175–178PubMedCrossRefGoogle Scholar
  37. Urao T, Yakubov B, Satoh R, Yamaguchi-Shinozaki K, Seki M, Hirayama T, Shinozaki K (1999) A transmembrane hybrid-type histidine kinase in Arabidopsis functions as an osmosensor. Plant Cell, in pressGoogle Scholar
  38. Usami S, Banno H, Ito Y, Nishihama R, Machida Y (1995) Cutting activates a 46kDa protein kinase in plants. Proc Natl Acad Sci USA 92 : 8660–8664PubMedCrossRefGoogle Scholar
  39. Wurgler-Murphy SM, Saito H (1997) Two-component signal transducers and MAPK cascades. TIBS 22 :172–176PubMedGoogle Scholar
  40. Zhang S, Klessig DF (1997) Salicylic acid activates a 48-kD MAP kinase in tobacco. Plant Cell 9: 809–824PubMedGoogle Scholar
  41. Zhang S, Klessig DF (1998a) Activation of the tobacco SIP kinase by both a cell wall-derived carbohydrate elicitor and purified proteinaceous elicitins from Phytophthora spp. Plant Cell 9: 809–824Google Scholar
  42. Zhang S, Klessig DF (1998b) The tobacco wounding-activated mitogen-activated protein kinase is encoded by SIPK. Proc Natl Acad Sci USA 95 : 7225–7230PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2000

Authors and Affiliations

  • Tsuyoshi Mizoguchi
    • 1
  • Kazuya Ichimura
    • 1
    • 2
  • Riichiro Yoshida
    • 1
  • Kazuo Shinozaki
    • 1
  1. 1.Laboratory of Plant Molecular Biology, The Institute of Physical and Chemical Research (RIKEN)Tsukuba Life Science CenterTsukuba, IbarakiJapan
  2. 2.Institute of Biological SciencesThe University of TsukubaTsukuba, IbarakiJapan

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