Abstract
The use of some form of cement as an alternative to direct mechanical fixation (press-fit, screws etc) dates back to the earliest period of joint replacement surgery. The first void-filling agent to be tried by Gluck in 1890 was a combination of plaster, pumice and resin. At this time there were no antibiotics, and the experiments failed for this and other obvious reasons [13]. When methyl methacrylate as a bone cement was made popular in the field of implant fixation in the 1960’s, antibiotics were available and the first documented use of antibiotic loaded bone cement occurred within this decade [4].
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Lundberg, A., Hedlund, H. (2007). Antibiotic Bone Cement as a Prophylactic Means in Joint Replacement Surgery. In: Meani, E., Romanò, C., Crosby, L., Hofmann, G., Calonego, G. (eds) Infection and Local Treatment in Orthopedic Surgery. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-47999-4_8
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DOI: https://doi.org/10.1007/978-3-540-47999-4_8
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