Abstract
The defect created by the osteomyelitic destruction and its debridement has always been seen as an important cause of non-healing. Surgeons therefore have tried to fill these cavities with all kinds of autogenous tissues and allogenic materials: patients own skin or muscle, plaster of Paris or gauzes. Since antiseptics were introduced, they have been mixed with these fillers, e.g. plaster of Paris with carbolic acid or cod liver oil [4, 8]. And the same happened with antibiotics, which were admixed with plaster of Paris, as well as to bone grafts or patient’s own blood.
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Walenkamp, G.H.I.M. (2007). Antibiotic Loaded Cement: From Research to Clinical Evidence. In: Meani, E., RomanĂ², C., Crosby, L., Hofmann, G., Calonego, G. (eds) Infection and Local Treatment in Orthopedic Surgery. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-47999-4_20
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DOI: https://doi.org/10.1007/978-3-540-47999-4_20
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