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References

  1. Kielley, R.K.: Purification and properties of thymidine monophosphate kinase from mouse hepatoma. J. Biol. Chem., 245, 4204–4212 (1970)

    PubMed  CAS  Google Scholar 

  2. Tamiya, N.; Yusa, T.; Yamaguchi, Y.; Tsukifuii, R.; Kuroiwa, N.; Moriyama, Y.; Fujimura, S.: Co-purification of thymidylate kinase and cytosolic thymidine kinase from human term placenta by affinity chromatography. Bio-chim. Biophys. Acta, 995, 28–35 (1989)

    CAS  Google Scholar 

  3. Bone, R.; Cheng, Y.C.; Wolfenden, R.: Inhibition of adenosine and thymidylate kinases by bisubstrate analogs. J. Biol. Chem., 261, 16410–16413 (1986)

    PubMed  CAS  Google Scholar 

  4. Jong, A.Y.S.; Campbell, J.L.: Characterization of Saccharomyces cerevisiae thymidylate kinase, the CDC8 gene product. General properties, kinetic analysis, and subcellular localization. J. Biol. Chem., 259, 14394–14398 (1984)

    PubMed  CAS  Google Scholar 

  5. Chen, M.C.; Walker, J.; Prusoff, W.H.: Kinetic studies of herpes simplex virus type 1-encoded thymidine and thymidylate kinase, a multifunctional enzyme. J. Biol. Chem., 254, 10747–10753 (1979)

    PubMed  CAS  Google Scholar 

  6. Lee, L.S.; Cheng, Y.C.: Human thymidylate kinase. Purification, characterization, and kinetic behavior of the thymidylate kinase derived from chronic myelocytic leukemia. J. Biol. Chem., 252, 5686–5691 (1977)

    PubMed  CAS  Google Scholar 

  7. Smith, L.K.; Eakin, R.E.: Partial purification and characterization of thymidylate kinase from embryonic chick liver. Arch. Biochem. Biophys., 167, 61–71 (1975)

    Article  CAS  Google Scholar 

  8. Rossi, M.; Woodward, D.O.: Enzymes of deoxythymidine triphosphate biosynthesis in Neurospora crassa mitochondria. J. Bacterid., 121, 640–647 (1975)

    CAS  Google Scholar 

  9. Cheng, Y.C.; Prusoff, W.H.: Mouse ascites sarcoma 180 thymidylate kinase. General properties, kinetic analysis, and inhibition studies. Biochemistry, 12, 2612–2619 (1973)

    Article  PubMed  CAS  Google Scholar 

  10. de Groot, E.J.; Schweiger, H.G.: Thymidylate kinase from Acetabularia. I. Properties of the enzyme. J. Cell Sci., 64, 13–25 (1983)

    PubMed  Google Scholar 

  11. Nelson, D.J.; Carter, C.E.: Purification and characterization of thymidine 5-monophosphate kinase from Escherichia coli B. J. Biol. Chem., 244, 5254–5262 (1969)

    PubMed  CAS  Google Scholar 

  12. Jong, A.Y.S.; Kuo, C.I.; Campbell, J.L.: The CDC8 gene of yeast encodes thymidylate kinase. J. Biol. Chem., 259, 11052–11059 (1984)

    PubMed  CAS  Google Scholar 

  13. Ostermann, N.; Segura-Pena, D.; Meier, C; Veit, T.; Monnerjahn, C; Konrad, M.; Lavie, A.: Structures of human thymidylate kinase in complex with prodrugs: implications for the structure-based design of novel compounds. Biochemistry, 42, 2568–2577 (2003)

    Article  PubMed  CAS  Google Scholar 

  14. Chenal-Francisque, V.; Tourneux, L.; Carniel, E.; Christova, P.; de la Sierra, I.; Barzu, O.; Gilles, A.-M.: The highly similar TMP kinase of Yersinia pestis and Escherichia coli differ markedly in their AZTMP phosphorylating activity. Eur. J. Biochem., 265, 112–119 (1999)

    Article  PubMed  CAS  Google Scholar 

  15. Tourneux, L.; Bucurenci, N.; Lascu, I.; Sakamoto, H.; Briand, G.; Gilles, A.-M.: Substitution of an alanine residue for glycine 146 in TMP kinase from Escherichia coli is responsible for bacterial hypersensitivity to bromodeox-yuridine. J. Bacterid., 180, 4291–4293 (1998)

    CAS  Google Scholar 

  16. Petit, CM.; Koretke, K.K.: Characterization of Streptococcus pneumoniae thymidylate kinase: steady-state kinetics of the forward reaction and isothermal titration calorimetry. Biochem. J., 363, 825–831 (2002)

    Article  PubMed  CAS  Google Scholar 

  17. Fioravanti, E.; Haouz, A.; Ursby, T.; Munier-Lehmann, H.; Delarue, M.; Bourgeois, D.: Mycobacterium tuberculosis thymidylate kinase: structural studies of intermediates along the reaction pathway. J. Mol. Biol, 327, 1077–1092 (2003)

    Article  PubMed  CAS  Google Scholar 

  18. terentyev, L.L.; Terentyeva, N.A.; Rasskazov, V.A.: Purification and some properties of thymidylate kinase from sea urchin. Biochemistry, 64, 80–85 (1999)

    PubMed  CAS  Google Scholar 

  19. Jacobsson, B.; Britton, S.; Tornevik, Y.; Eriksson, S.: Decreas in thymidylate kinase activity in peripheral blood mononuclear cells from HIV-infected individuals. Biochem. Pharmacol, 56, 389–395 (1998)

    Article  PubMed  CAS  Google Scholar 

  20. Munier-lehmann, H.; Chaffotte, A.; Pochet, S.; Labesse, G.: Thymidylate kinase of Mycobacterium tuberculosis: a chimera sharing properties common to eukaryotic and bacterial enzymes. Protein Sci., 10, 1195–1205 (2001)

    Article  PubMed  CAS  Google Scholar 

  21. Ostermann, N.; Schlichting, I.; Brundiers, R.; Konrad, M.; Reinstein, J.; Veit, T.; Goody, R.S.; Lavie, A.: Insights into the phosphoryltransfer mechanism of human thymidylate kinase gained from crystal structures of enzyme complexes along the reaction coordinate. Structure, 8, 629–642 (2000)

    Article  PubMed  CAS  Google Scholar 

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(2007). dTMP Kinase. In: Schomburg, D., Scomburg, I., Chang, A. (eds) Springer Handbook of Enzymes. Springer Handbook of Enzymes, vol 37. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-47818-8_81

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