Specification of Zebrafish Neural Crest

  • Robert N. Kelsh
  • David W. Raible
Part of the Results and Problems in Cell Differentiation book series (RESULTS, volume 40)


The neural crest is a tissue unique to vertebrates. It consists characteristically of a set of cells that sit transiently in a position dorsal or lateral to the forming or formed neural tube. The cells are ectodermally derived, appearing at the boundary between neural plate and non-neural ectoderm. Soon after their formation, most neural crest cells migrate away from the neural tube to generate a variety of cell types, including peripheral neurons and glia, pigment cells, and the craniofacial mesenchyme that forms cartilage and bone in the head. In this chapter, we will discuss how neural crest cells become specified, highlighting contributions that research in zebrafish has made to our understanding of these processes.


Neural Crest Neural Crest Cell Pigment Cell Medial Pathway Neural Crest Development 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Copyright information

© Springer-Verlag Berlin Heidelberg 2002

Authors and Affiliations

  • Robert N. Kelsh
    • 1
  • David W. Raible
    • 2
  1. 1.Developmental Biology Programme, Department of Biology and BiochemistryUniversity of BathClaverton Down, BathUK
  2. 2.Department of Biological StructureUniversity of WashingtonSeattleUSA

Personalised recommendations