Specification of Zebrafish Neural Crest
The neural crest is a tissue unique to vertebrates. It consists characteristically of a set of cells that sit transiently in a position dorsal or lateral to the forming or formed neural tube. The cells are ectodermally derived, appearing at the boundary between neural plate and non-neural ectoderm. Soon after their formation, most neural crest cells migrate away from the neural tube to generate a variety of cell types, including peripheral neurons and glia, pigment cells, and the craniofacial mesenchyme that forms cartilage and bone in the head. In this chapter, we will discuss how neural crest cells become specified, highlighting contributions that research in zebrafish has made to our understanding of these processes.
KeywordsNeural Crest Neural Crest Cell Pigment Cell Medial Pathway Neural Crest Development
Unable to display preview. Download preview PDF.