Skip to main content

Proteins and Patients — Magnetic Nanoparticles as Analytic Markers

  • Chapter
  • 1083 Accesses

Part of the Advances in Solid State Physics book series (ASSP,volume 46)

Abstract

Exciting new applications of low noise magnetic sensors in biotechnology, medical diagnosis and therapy are at hand for magnetic nanoparticles (MNP), which are already used in the clinical routine. The relaxation of magnetic nanoparticles is a fascinating method which can be employed for the characterization of ferrofluids and is further developed as analytical tool for biochemistry. In this article the basics and methods of the characterization of diluted ferrofluids by magnetore-laxometry (MRX) are described. We start with the properties of the ferrofluid which consists of magnetic nanoparticles. The time schedule for relaxation measurements is discussed. The details of our fluxgate based experimental set-up are presented. To achieve high sensitivity even at low concentrations of magnetic nanoparticles we optimize fluxgate sensors for low intrinsic noise, high sensitivity and large bandwidth.

Keywords

  • Magnetic Nanoparticles
  • Magnetic Signal
  • Anisotropy Energy
  • Magnetic Relaxation
  • Relaxation Time Constant

These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

This is a preview of subscription content, access via your institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • DOI: 10.1007/978-3-540-38235-5_7
  • Chapter length: 11 pages
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
eBook
USD   189.00
Price excludes VAT (USA)
  • ISBN: 978-3-540-38235-5
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Softcover Book
USD   249.99
Price excludes VAT (USA)
Hardcover Book
USD   249.99
Price excludes VAT (USA)

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. F. Ludwig, E. Heim, D. Menzel, M. Schilling, J. Appl. Phys. 99, (2006).

    Google Scholar 

  2. R. Kötitz, L. Trahms, H. Koch, W. Weitschies, in Biomagnetism: Fundamental Research and Clinical Applications, edited by C. Baumgartner, L. Deecke, S. J. Williamson (Elsevier Science, Amsterdam, 1995), p. 785.

    Google Scholar 

  3. Y. R. Chemla, H. L. Grossmann, Y. Poon, R. McDermott, R. Stevens, M. D. Alper, J. Clarke, Proc. Natl. Acad. Sci. USA 97, 14268 (2000).

    CrossRef  ADS  Google Scholar 

  4. F. Ludwig, E. Heim, S. Mäuselein, D. Eberbeck, M. Schilling, J. Magn. Magn. Mater. 293, 690 (2005).

    CrossRef  ADS  Google Scholar 

  5. E. Heim, F. Ludwig, M. Schilling, Biomed. Tech. 49, 420 (2004).

    Google Scholar 

  6. F. Ludwig, S. Mäuselein, E. Heim, M. Schilling, Rev. Sci. Instr. 76, 106102–1 (2005).

    CrossRef  ADS  Google Scholar 

  7. C. Hinnrichs, C. Pels, M. Schilling, J. Appl. Phys. 87, 7085 (2000).

    CrossRef  ADS  Google Scholar 

  8. D. Eberbeck, S. Hartwig, U. Steinhoff, L. Trahms, Magnetohydrodynamics 39, 77 (2003).

    ADS  Google Scholar 

  9. L. Néel, Adv. Phys. 4, 191 (1955).

    CrossRef  ADS  Google Scholar 

  10. E. Heim, F. Ludwig, M. Schilling, Biomed. Tech. 50, 613 (2005).

    Google Scholar 

  11. E. Heim, S. Harling, F. Ludwig, H. Menzel, M. Schilling, to be published.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and Permissions

Copyright information

© 2008 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Schilling, M., Ludwig, F. (2008). Proteins and Patients — Magnetic Nanoparticles as Analytic Markers. In: Advances in Solid State Physics. Advances in Solid State Physics, vol 46. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-38235-5_7

Download citation