This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
Literatur
Adlercreutz H (1995) Phytoestrogens: epidemiology and a possible role in cancer protection. Environ Health Perspect 103(Suppl 7): 103–112
Artaud-Wild SM, Connor SL, Sexton G et al. (1993) Differences in coronary mortality can be explained by differences in cholesterol and saturated fat intakes in 40 countries but not in France and in Finland. A paradox. Circulation 88: 2771–2779
Bairati I, Meyer F, Gelinas M et al. (2005) A randomized trial of antioxidant vitamins to prevent second primary cancers in head and neck cancer patients. J Natl Cancer Inst 97: 481–488
Belitz H-D, Grosch W, Schieberle P (2001) Lehrbuch der Lebensmittelchemie, 5. Aufl. Springer, Berlin Heidelberg New York Tokio
Berger M, Mühlhauser I (1996) Surrogat-Marker: Trugschlüsse. Dt Ärztebl 93: A–3280
Bjelakovic G, Nikolova D, Simonetti RG, Gluud C (2004) Antioxidant supplements for preventing gastrointestinal cancers (Cochrane Review). Cochrane database Syst Rev 4: CD004183; s. auch: Lancet 2004; 364: 1219–1228
Brenner H, Rothenbacher D, Bode G, Maez W et al. (2001) Coronary heart disease risk reduction in a predominantly beer-drinking population. Epidemiology 12: 380–382
Burkart V, Wang ZQ, Radons J et al. (1999) Mice lacking the poly (ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction induced by streptozotocin. Nature Med 5: 314–319
Cassidy A (1996) Physiologcal effects of phyto-estrogens in relation to cancer and other human health risks. Proceeding Nutr Soc 55: 399–417
Cassidy A, Bingham S, Setchell KDR (1994) Biological effects of soyprotein rich in isoflavones on the menstrual cycle of premenopausal women. Am J Clin Nutr 74: 333–340
Cassidy A, Bingham S, Setchell KDR (1995) Biological effects of isoflavones in young women: importance of the chemical composition of soybean products. Brit J Nutr 74: 587–601
Chen C, Pung D, Leong V et al. (2004) Induction of detoxifying enzymes by garlic organosulfur compounds through transcription factor Nrf2: effect of chemical structure and stress signal. Free Radic Biol Med 37: 1578–1580
Clark RF, Strukle E, Williams SR, Manoguerra AS (1996) Selenium poisoning from a nutritional supplement. JAMA 275: 1087–1088
Fam SS, Morrow JD (2003) The isoprostanes: unique products of arachidonic acid oxidation — a review. Curr Medicin Chem 10: 1723–1740
Ferrières J (2004) The French paradox: lessons for other countries. Heart 90: 107–111
Germain AS, Peterson CD, Robinson JG, Alekel DL (2001) Isoflavonerich or isoflavone-poor soy protein does not reduce menopausal symptoms during 24 weeks of treatment. J Americ Menopausal Soc 8: 17–22
Ghosal S, Triethi VK, Chauhan S (1996) Active constituents of Emblica officinalis: Part 1: The chemistry and antioxidative effects of two new hydrolysable tannins, emblicanin A and B. Indian J Chem 35B: 941–948; zit. http: //www.itmonline.org/arts/amla.htm
Gils van CH, Peeters PH, Bueno-de-Mequita HB et al. (2005) Consumption of vegetables and fruits and risk of breast cancer. JAMA 293: 1183–1193
Giudetti AM, Sabetta S, di Summa R et al. (2003) Differential effects of coconut oil-and fish oil-enriched diets on tricarboxylate carrier in rat liver mitochondria. J Lipid Res 44: 2135–2141
Grune T, Merker K, Siems W (2002) Lebenslange Attacke tötet Zellen. Pharmaz Ztg 44: 4208–4214
Haas H (1956) Spiegel der Arznei. Ursprung, Geschichte und Idee der Heilmittelkunde. Springer, Berlin Göttingen Heidelberg, S 125
Harman D (1956) Aging: a theory based on free radical and radiation chemistry. J Gerontol 11: 298–300
Harman D (1992) Free radical theory of aging. Mutat Res 275: 257–266
Harman D (1996) Aging and disease: extending functional life span. Ann NY Acad Sci 786: 362–378
Heinecke JW (2001) Is the emperor wearing clothes? Clinical trials of vitamin E and the LDL oxidation hypothesis. Arterioscler Thromb Vasc Biol 21: 1261–1264
Holzbeierlein JM, McIntosh J, Thrasher JB (2005) The role of soy phytoestrogens in prostrate cancer. Curr Opin Urol 15: 17–22
Hughes CL, Liu G, Beall S, Foster WG, Davis V (2004) Effects of genistein or soy milk during late gestation and lactation on adult uterine organization in the rat. Exp Biol Med 229: 108–117
Hung HC, Joshipura KJ, Jiang R (2004) Fruit and vegetable intake and risk of major chronic disease. J Natl Cancer Inst 96: 1577–1584
Hussain SP, Hofseth LJ, Harris CC (2003) Radical causes of cancer. Nature Rev Cancer 3: 276–285
Ishizuki Y, Hirooka Y, Murata Y et al. (1991) The effect on the thyroid gland of soybeans administered experimentally in health subjects. Nippon naibunpi gakkai Zasshi 67: 622–629; zitiert bei: Ministry of Health http: //www.moh.govt.nz (Dezember 1998)
Jabbar MA, Larrea J, Shaw RA (1997) Abnormal thyroid function tests in infants with congenital hypothyroidism: the influence of soy based formula. J Am College Nutr 3: 280–282
Janssen K, Mensink RP, Cox FJ et al. (1998) Effects of flavonoids quercetin and apigenin on hemostasis in healthy volunteers: results from an in vitro and a dietary supplement. Am J Clin Nutr 67: 255–262
Jungermann K, Möhler H (1980) Biochemie. Springer, Berlin Heidelberg New York, S 627
Kasper H (1996) Ernährungsmedizin und Diätetik. Urban & Schwarzenberg, München Wien Baltimore, S 215 und S 281–285
Kinscherf R, Metz J (2000) Die Bedeutung des oxidativen Stresses für Gefäßwandveränderungen. Dtsch Zeitschr Sportmedizin 51: 6–10
Klein SL, Wisniewski AB, Marson AL, Glass GE, Gearhart JP (2002) Early exposure to genistein exerts long-lasting effects on the endocrine and immune systems in rats. Mol Med 8: 742–749
Koch HP, Lawson LD (1996) Garlic: The science and therapeutic applications of Allium sativum L. and related species. Williams & Wilkins, Baltimore
Lau BHS (2001) Suppression of LDL oxidation by garlic. J Nutrition 131: 985S–988S
Lawson LD (1998) Garlic: A review of its medical effects and indicated active compounds. In: Lawson Ld, Bauer R (eds) Phytomedicines of Europe: Chemistry and Biological activity, ACS Symposium Series 691, American Chemical Society, Washington DC, pp 176–209
Lebedev AV, Levitzky DO, Loginov VA (1980) Oxygen: an inductor of calcium ion transfer via bilayer lipid membrane. Dokl Akad Med Nauk SSSR 252: 1494–1497
Li H, Stampfer MJ, Giovanucci EL et al. (2004) A prospective study of plasma selenium levels and postrate cancer risk. J Natl Cancer Inst 96: 696–703
Lim P, Wuenschell GE, Holland V et al. (2004) Peroxyl radical mediated oxidative DNA base damage: implications for lipid peroxidation induced mutagenesis. Biochemistry 43: 15339–15348
Löffler G, Petrides PE (Hrsg) (2003) Biochemie und Pathobiochemie. 7. Aufl. Springer, Berlin Heidelberg New York, S 550
Macpherson LJ, Geierstanfer BH, Viswanath V et al. (2005) The pungency of garlic: activation of TRPA1 and TRPVa in response to allicin. Curr Biol 15: 929–934
Maxwell S, Cruickshank A, Thorpe G (1994) Red wine and antioxidant activity in serum. Lancet 344: 193–194
Meerson FZ (1984) Adaptation, stress, and prophylaxis. Translates from the Russian by Joseph Shapiro. Springer, Berlin Heidelberg New York Tokyo, p 249
Metz G (2001) Phytamine — Pflanzliche Nahrung zur Prävention. PZ Schriftenreihe 13, Govi-Verlag, Pharmazeutischer Verlag, Eschborn, S 49–51, 77
Milner JA (2001) Mechanisms by which garlic and allyl sulfur compounds suppress carcinogen bioactivation. Garlic and carcinogens. Adv Exp Med Biol 492: 69–81
Müller T (2005) Viel Obst, Gemüse und Fisch sind gesund — potentielle Krebszellen lassen sich davon aber kaum beeindrucken. Ärzte Zeitung vom 19.01.2005
Muntwyler J, Hennekens CH, Buring JE, Gaziano JM (1998) Mortality and light to moderate alcohol consumption after myocardial infarction. Lancet 352: 1882–1885
Newbold RR, Banks EP, Bullock B, Jefferson WN (2001) Uterine adenocarcinoma in mice treated neonatally with genistein. Cancer Res 61: 4325–4328
Oshima H, Tatemichi M, Sawa T (2003) Chemical basis of inflam mation-induced carcinogenesis. Arch Biochem Biophys 417: 3–11
Pamplona R, Portero-Otim M, Riba D et al. (1998) Mitochondrial membrane peroxidizability index is inversely related to maximum life span in ammals. J Lipid Res 39: 1989–1994
Pamplona R, Barja G, Portero-Otín M (2002) Membrane fatty acid unsaturation, protection against oxidative stress, and maximum life span. Annals New York Acad Sci 959: 475–490
Piro S, Anello M, Di Pietro C et al. (2002) Chronic exposure to free fatty acids or high glucose induces apoptosis in rat pancreatic islets: possible role of oxidative stress. Metabolism 51: 1340–1347
Portero-Otin M, Bellmunt MJ, Ruiz MC, Barja G, Pamplona R (2001) Correlation of fatty acid unsaturation of the major liver mitochondrial phospholipd classes in mammals to their maximum life span potential. Lipids 36: 491–498
Reaven P, Parthasarathy S, Grasse BJ (1991) Feasibility of using an oleate-rich diet to reduce the susceptibility of low-density lipoprotein to oxidative modification in humans. Americ J Clinic Nutrition 54: 701–706
Richard JL, Cambien F, Ducimetière P (1981) Epidemiologic characteristics of coronary disease in France. Nouv Presse Med 10: 1111–1114
Rösen P (2004) Diabetes und oxidativer Stress. Blickpunkt Der Mann 2: 23–30
Rohr U (2004) Soja und Rotklee. Phytoestrogene in der Prävention. Pharm Ztg 149: 3949–3959
Roth HJ (2002) Du sollst den Roten nicht über den grünen Klee loben. Deutsche Apoth Ztg 142: 4144–4147
Sabichi AL, Lee JJ, Taylor RJ et al. (2002) Selenium accumulates in prostrate tissue of prostrate cancer patients after short-time administration of Selenomethionin. Proc Am Assoc Cancer Res 43: 1007–1008
Salonen JT, Alfthan G, Huttunen JK et al. (1982) Association between cardiovascular death and myocardial infarction and serum selenium in a matched-pair longitudinal study. Lancet 24: 175–179
Schlee D (1992) Ökologische Biochemie. Fischer, Jena Stuttgart New York, S 307
Schultz V, Hänsel R (2004) Rationale Phytotherapie. 5. Aufl. Springer, Berlin Heidelberg New York, S 161–186
Setchell KDR, Zimmer-Nechemias L, Cal J, Heubl JE (1997) Exposure of infants to phytoestrogens from soy-based infant formula. Lancet 350: 23–27
Shukla A, Dikshit M, Srimal RC (1995) Status of antioxidants in brain microvessels of monkeys and rat. Free Rad Res 22: 303–308
Siegmund S, Teyssen S, Singer MV (2002) Alkoholassoziierte Organschäden. Gesundheitliche Folgen durch moderaten Alkoholkonsum. Internist 43: 287–293
Sies H, Stahl W, Klotz L-O, Brenneisen B (2003) Oxidativer Stress: vom molekularen Mechanismus zur Klinik. Jahrbücher der Heinrich-Heine-Universität, ohne Bandangabe, S 101–116
Song JH, Miyazawa T (2001) Enhanced level of ω-3 fatty acid in membrane phospholipids induces lipid peroxidation in rats fed dietary docohexaenoic acid oil. Atherosclerosis 155: 9–18
Steinberg D, Witztum JL (2002) Is the oxidative modification hypothesis relevant to human atherosclerosis? Circulation 105: 2107–2111
Stob M (1983) Naturally occurring food toxicants: estrogens. In: Handbook of naturally occurring food toxicants. CRC Press, New York, pp 81–100
Stryer L (1990) Biochemie. Spektrum der Wissenschaft Verlagsgesellschaft. Heidelberg, S 648
Taylor PR, Parnes HL, Lippman SM (2004) Science peels the onion of selenium effects on prostrate carcinogenesis. JNCI 96: 645–647
Thun MJ, Peto R, Lopez AD et al. (1997) Alcohol consumption and mortality among middle-aged and elderly US adults. N Eng J Med 337: 1705–1714
Tuohy P (1995) Soy based infant formula. Prescriber Update 10: 2–8; s. auch Ministry of Health http: //www.moh.govt.nz (Dezember 1998)
Valko M, Izakovic M, Mazur M et al. (2004) Role of oxygen radicals in DNA damage and cancer incidence. Mol Cell Biochem 266: 37–56
Vinson JA, Bose P (1988) Comparative bioavailability to humans of ascorbic acid alone or in a citrus extract. Am J Clin Nutr 48: 601–604
Vinson JA, Jang J (2001) In vitro and in vivo lipoprotein antioxidant effect of a Citrus extract and ascorbic acid on normal and hypercholesterolemic human subjects. J Med Food 4: 187–192
Whanger P, Vendeland S, Park YC, Xia Y (1996) Metabolism of subtoxic levels of selenium in animals and humans. Ann Clin Lab Sci 26: 99–113
Willett WC, Hubter DJ, Stampfer MJ et al. (1992) Dietary fat and fiber in relation to risk of breast cancer. An 8-year follow-up. JAMA 268: 2037–2044
Wisniewski AB, Klein SL, Lakshmanan Y, Gearhart JP (2003) Exposure to genistein during gestation and lactation demasculinizes the reproductive system in rats. J Urol 169: 1582–1586
Wisniewski AB, Cernetich A, Gearhart JPm Klein SL (2005) Perinatal exposure to genistein alters reproductive development and aggressive behaviour in male mice, Physiol Behav 84: 327–334
Wolfram S (2005) Spurenelemente. In: Aktories K, Förstermann U, Hofmann F, Starke K (Hrsg) Allgemeine und spezielle Pharmakologie und Toxikologie. 9. Aufl. Urban & Fischer, München Jena, S 765–772
Wolters M, Hahn A (2004) Wissenschaftlich nicht haltbar. (Stellungnahme zum Beitrag Rohr U loc.cit.) Pharm Ztg 149: 4282–4284
Younes M (1994) Freie Radikale und reaktive Sauerstoff spezies. In: Marquardt H, Schäfer S (Hrsg) Lehrbuch der Toxikologie. BI Wissenschaftsverlag, Mannheim Leipzig Wien Zürich, S 94–105
Zimmerli B, Schlatter J (1997) Phytoestrogens in baby food based on soya bean protein. Paediatrica 8: 219–232
Weiterfühhrende Literatur
Brandt U (2003) Redoxreaktionen, Sauerstoff und oxidative Phosphorylierung. In: Löffler G, Petrides PE (Hrsg) Biochemie und Pathobiochemie. 7. Aufl. Springer, Berlin Heidelberg New York Tokio, S 531–555
Chisolm GM, Steinberg D (2000) The oxidative modification hypothesis of atherogenesis: an overview. Free Radic Biol Med 28: 1815–1826
Dekant W, Vamvakas S (1994) Toxikologie für Chemiker und Biologen. Spektrum Akademischer Verlag, Heidelberg Berlin Oxford
de Villiers WJ, Smart EJ (1999) Macrophage scavenger receptors and foam cell formation. J Leucoc Biol 66: 740–746
Elsenhals B (2005) Vitamine und Spurenelemente — Therapie des Vitaminmangels. In: Aktories K, Förstermann U, Hofmann F, Starke K (Hrsg) Allgemeine und spezielle Pharmakologie und Toxikologie. 9. Aufl. Urban & Fischer, München Jena, S 749–772
Herder Lexikon der Biochemie und Molekularbiologie (1995) Spektrum Akademischer Verlag, Heidelberg Berlin Oxford
Kasper H (2004) Ernährungsmedizin und Diätetik. 10. Aufl. Urban & Fischer, München Jena
Stocker R, Keany JF (2004) Role of oxidation modification in atherosclerosis. Physiol Rev 84: 1381–1478
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2007 Springer Medizin Verlag Heidelberg
About this chapter
Cite this chapter
Hänsel, R. (2007). Sekundäre Pflanzenstoffe in Nahrungsergänzungsmitteln. In: Hänsel, R., Sticher, O. (eds) Pharmakognosie — Phytopharmazie. Springer, Berlin, Heidelberg . https://doi.org/10.1007/978-3-540-34281-6_15
Download citation
DOI: https://doi.org/10.1007/978-3-540-34281-6_15
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-26508-5
Online ISBN: 978-3-540-34281-6
eBook Packages: Life Science and Basic Disciplines (German Language)