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Optic Disc Drusen

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Pediatric Ophthalmology, Neuro-Ophthalmology, Genetics

Part of the book series: Essentials in Ophthalmology ((ESSENTIALS))

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Abstract

■ Optic disc drusen (ODD) represent a frequent cause of slowly progressive optic neuropathy.

■ ODD result probably from an abnormal axonal metabolism, leading to mitochondrial calcification at the level of the lamina cribrosa. Axons rupture and extracellular mitochondria further calcify.

■ Buried (deep) ODD are more commonly seen in younger patients and exposed (superficial) ODD in older patients.

■ Visual field defects are a frequent finding in ODD patients, more so when ODD are exposed.

■ Visual acuity is usually preserved even in advanced but uncomplicated ODD.

■ Visual acuity loss can result from vascular complications such as: anterior ischemic optic neuropathy, central/branch retinal artery or vein occlusion.

■ The most sensitive diagnostic test for ODD is B-scan ultrasound.

■ There is currently no therapy for ODD.

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Authors and Affiliations

  1. Department of Neuro-Ophthalmology, Hôpital Ophtalmique Jules Gonin, Avenue de France 15, 1004, Lausanne, Switzerland

    Francois-Xavier Borruat

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  1. Francois-Xavier Borruat
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Birgit Lorenz Francois-Xavier Borruat

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Borruat, FX. (2008). Optic Disc Drusen. In: Lorenz, B., Borruat, FX. (eds) Pediatric Ophthalmology, Neuro-Ophthalmology, Genetics. Essentials in Ophthalmology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-33679-2_3

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  • DOI: https://doi.org/10.1007/978-3-540-33679-2_3

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-33678-5

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