Skip to main content
SpringerLink
Log in

CT-Guided Tumor Ablation

  • Chapter
Multislice CT

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

  • 2193 Accesses

Abstract

Percutaneous thermal ablation therapies have been receiving increasing attention as potential primary treatments for focal HCC and liver metastases. Possible advantages of ablative therapies as compared to surgical resection include a lower morbidity and mortality rate, lower costs, the suitability for real time imaging guidance, the option to perform ablative procedures on outpatients, and the potential application to a wider spectrum of patients, including those who are unsuitable as surgical candidates. Therefore, the major advantage of RFA is its ability to create a well-controlled focal thermal injury in the liver resulting in high success rates in treating HCC nodules and metastases smaller than 3 cm in diameter with long-term outcome results comparable to surgery. Besides the accepted application of thermal ablation in patients suffering from liver tumors, RFA has a rapidly growing role in tumors beyond the liver. Especially in renal and lung cancer, RF ablation shows very promising results; however, larger studies are still missing proving its effectiveness regarding the long-term follow-up.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Allaf ME, Varkarakis IM, Bhayani SB et al. (2005) Pain control requirements for percutaneous ablation of renal tumors: cryoablation versus radiofrequency ablation—initial observations. Radiology 237:366–370

    Article  PubMed  Google Scholar 

  • Bilchik AJ, Wood TF, Allegra DP (2001) Radiofrequency ablation of unresectable hepatic malignancies: lessons learned. Oncologist 6: 24–33

    Article  PubMed  CAS  Google Scholar 

  • Buscarini L, Buscarini E (2001) Therapy of HCC radiofrequency ablation. Hepatogastroenterology 48:15–19

    PubMed  CAS  Google Scholar 

  • Buscarini L, Buscarini E, Di Stasi M et al. (2001) Percutaneous radiofrequency ablation of small hepatocellular carcinoma: long-term results. Eur Radiol 11:914–921

    Article  PubMed  CAS  Google Scholar 

  • Curley SA, Izzo F, Delrio P et al. (1999) Radiofrequency ablation of unresectable primary and metastatic hepatic malignancies: results in 123 patients. Ann Surg 230:1–8

    Article  PubMed  CAS  Google Scholar 

  • Curley SA, Izzo F, Ellis LM et al. (2000) Radiofrequency ablation of hepatocellular cancer in 110 patients with cirrhosis. Ann Surg 232:381–391

    Article  PubMed  CAS  Google Scholar 

  • Curley SA (2003) Radiofrequency ablation of malignant liver tumors. Ann Surg Oncol 10:338–347

    Article  PubMed  Google Scholar 

  • Curley SA, Marra P, Beaty K et al. (2004) Early and late complications after radiofrequency ablation of malignant liver tumors in 608 patients. Ann Surg 239:450–458

    Article  PubMed  Google Scholar 

  • de Baere T, Elias D, Dromain C et al. (2000) Radiofrequency ablation of 100 hepatic metastases with a mean follow-up of more than 1 year. AJR Am J Roentgenol 175:1619–1625

    PubMed  Google Scholar 

  • Gillams AR, Lees WR (2004) Radio-frequency ablation of colorectal liver metastases in 167 patients. Eur Radiol 14:2261–2267

    Article  PubMed  CAS  Google Scholar 

  • Goetz MP, Callstrom MR, Charboneau JW et al. (2004) Percutaneous image-guided radiofrequency ablation of painful metastases involving bone: a multicenter study. J Clin Oncol 22:300–306

    Article  PubMed  Google Scholar 

  • Goldberg SN and Gazelle GS (2001) Radiofrequency tissue ablation: physical principles and techniques for increasing coagulation necrosis. Hepatogastroenterology 48:359–367

    PubMed  CAS  Google Scholar 

  • Haber GP, Gill IS (2006) Laparoscopic partial nephrectomy: contemporary technique and outcomes. Eur Urol 49:660–665

    Article  PubMed  Google Scholar 

  • Hacker A, Vallo S, Weiss C et al. (2005) Minimally invasive treatment of renal cell carcinoma: comparison of four different monopolar radiofrequency devices. Eur Urol 48:584–592

    Article  PubMed  Google Scholar 

  • Helmberger T, Dogan S, Straub G et al. (2007) Liver resection or combined chemoembolization and radiofrequency ablation improve survival in patients with hepatocellular carcinoma. Digestion 75:104–112

    Article  PubMed  Google Scholar 

  • Hoffmann RT, Jakobs TF, Lubienski A et al. (2006) Percutaneous radiofrequency ablation of pulmonary tumors—is there a difference between treatment under general anaesthesia and under conscious sedation? Eur J Radiol 59:168–174

    Article  PubMed  CAS  Google Scholar 

  • Johnson DB, Solomon SB, Su LM et al. (2004) Defining the complications of cryoablation and radio frequency ablation of small renal tumors: a multi-institutional review. J Urol 172:874–877

    Article  PubMed  Google Scholar 

  • Kelekis AD, Thanos L, Mylona S et al. (2006) Percutaneous radiofrequency ablation of lung tumors with expandable needle electrodes: current status. Eur Radiol 16:2471–2482

    Article  PubMed  CAS  Google Scholar 

  • Lencioni R, Cioni D, Crocetti L et al. (2005a) Early-stage hepatocellular carcinoma in patients with cirrhosis: long-term results of percutaneous image-guided radiofrequency ablation. Radiology 234:961–967

    Article  Google Scholar 

  • Lencioni R, Della Pina C, Bartolozzi C (2005b) Percutaneous image-guided radiofrequency ablation in the therapeutic management of hepatocellular carcinoma. Abdom Imaging 30:401–408

    Article  CAS  Google Scholar 

  • Liu LX, Jiang HC, Piao DX (2002) Radiofrequence ablation of liver cancers. World J Gastroenterol 8:393–399

    PubMed  Google Scholar 

  • Livraghi T, Meloni F (2001) Removal of liver tumours using radiofrequency waves. Ann Chir Gynaecol 90:239–245

    PubMed  CAS  Google Scholar 

  • Livraghi T, Solbiati L, Meloni MF et al. (2003) Treatment of focal liver tumors with percutaneous radio-frequency ablation: complications encountered in a multicenter study. Radiology 226:441–451

    Article  PubMed  Google Scholar 

  • Lotan Y, Cadeddu JA (2005) A cost comparison of nephron-sparing surgical techniques for renal tumour. BJU Int 95:1039–1042

    Article  PubMed  Google Scholar 

  • McGahan JP, Browning PD, Brock JM et al. (1990) Hepatic ablation using radiofrequency electrocautery. Invest Radiol 25:267–270

    Article  PubMed  CAS  Google Scholar 

  • McGahan JP, Gu WZ, Brock JM et al. (1996) Hepatic ablation using bipolar radiofrequency electrocautery. Acad Radiol 3:418–422

    Article  PubMed  CAS  Google Scholar 

  • Mouraviev V, Joniau S, Van Poppel H et al. (2007) Current status of minimally invasive ablative techniques in the treatment of small renal tumours. Eur Urol 51:328–336

    Article  PubMed  Google Scholar 

  • Mulier S, Mulier P, Ni Y et al. (2002) Complications of radiofrequency coagulation of liver tumours. Br J Surg 89:1206–1222

    Article  PubMed  CAS  Google Scholar 

  • Ohlsson B, Stenram U, Tranberg KG (1998) Resection of colorectal liver metastases: 25-year experience. World J Surg 22:268–276; discussion 276–267

    Article  Google Scholar 

  • Pereira PL, Trubenbach J, Schmidt D (2003) [Radiofrequency ablation: basic principles, techniques and challenges]. Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr 175:20–27

    Article  PubMed  CAS  Google Scholar 

  • Poon RT, Fan ST, Tsang FH et al. (2002) Locoregional therapies for hepatocellular carcinoma: a critical review from the surgeon’s perspective. Ann Surg 235:466–486

    Article  PubMed  Google Scholar 

  • Scheele J, Stang R, Altendorf-Hofmann A et al. (1995) Resection of colorectal liver metastases. World J Surg 19:59–71

    Article  PubMed  CAS  Google Scholar 

  • Solbiati L, Ierace T, Tonolini M et al. (2001) Radiofrequency thermal ablation of hepatic metastases. Eur J Ultrasound 13:149–158

    Article  PubMed  CAS  Google Scholar 

  • Tateishi R, Shiina S, Teratani T et al. (2005) Percutaneous radiofrequency ablation for hepatocellular carcinoma. An analysis of 1,000 cases. Cancer 103:1201–1209

    Article  PubMed  Google Scholar 

  • Tranberg KG (2004) Percutaneous ablation of liver tumours. Best Pract Res Clin Gastroenterol 18:125–145

    Article  PubMed  Google Scholar 

  • Uzzo RG, Novick AC (2001) Nephron sparing surgery for renal tumors: indications, techniques and outcomes. J Urol 166:6–18

    Article  PubMed  CAS  Google Scholar 

  • Woertler K, Vestring T, Boettner F et al. (2001) Osteoid osteoma: CT-guided percutaneous radiofrequency ablation and follow-up in 47 patients. J Vasc Interv Radiol 12:717–722

    Article  PubMed  CAS  Google Scholar 

  • Wood TF, Rose DM, Chung M et al. (2000) Radiofrequency ablation of 231 unresectable hepatic tumors: indications, limitations, and complications. Ann Surg Oncol 7:593–600

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Clinical Radiology, Ludwig-Maximilians-University of Munich, Marchioninistrasse 15, 81377, Munich, Germany

    Ralf-Thorsten Hoffmann, Tobias F. Jakobs, Christoph G. Trumm & Maximilian F. Reiser

Authors
  1. Ralf-Thorsten Hoffmann
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Tobias F. Jakobs
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Christoph G. Trumm
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Maximilian F. Reiser
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Munich University Hospital, Institute of Clinical Radiology, Ludwig-Maximilians University, Marchioninistr. 15, 81377, Munich, Germany

    Maximilian F. Reiser , C.R. Becker  & Konstantin Nikolaou ,  & 

  2. School of Medicine, Department of Radiology, Stanford University, 1201 Welch Road, 94304, Palo Alto, CA, USA

    Gary Glazer

Rights and permissions

Reprints and permissions

Copyright information

© 2009 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Hoffmann, RT., Jakobs, T., Trumm, C., Reiser, M. (2009). CT-Guided Tumor Ablation. In: Reiser, M., Becker, C., Nikolaou, K., Glazer, G. (eds) Multislice CT. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-33125-4_39

Download citation

  • DOI: https://doi.org/10.1007/978-3-540-33125-4_39

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-33124-7

  • Online ISBN: 978-3-540-33125-4

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation