Skip to main content

Hidradenitis Suppurativa and Crohn’s Disease

  • Chapter
Hidradenitis Suppurativa

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 229.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 299.00
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 249.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Cosnes J. Tobacco and IBD: relevance in the understanding of disease mechanisms and clinical practice. Best Pract Res Clin Gastroenterol 2004;18:481–96.

    Article  PubMed  CAS  Google Scholar 

  2. Hugot JP, Chamaillard M, Zouali H, Lesage S, Cezard JP, Belaiche J, Almer S, Tysk C, O’Morain CA, Gassull M, Binder V, Finkel Y, Cortot A, Modigliani R, Laurent-Puig P, Gower-Rousseau C, Macry J, Colombel JF, Sahbatou M, Thomas G. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn’s disease. Nature 2001;411:599–603.

    Article  PubMed  CAS  Google Scholar 

  3. Ogura Y, Bonen DK, Inohara N, Nicolae DL, Chen FF, Ramos R, Britton H, Moran T, Karaliuskas R, Duerr RH, Achkar JP, Brant SR, Bayless TM, Kirschner BS, Hanauer SB, Nunez G, Cho JH. A frameshift mutation in NOD2 associated with susceptibility to Crohn’s disease. Nature 2001;411:603–6.

    Article  PubMed  CAS  Google Scholar 

  4. Girardin SE, Boneca IG, Viala J, Chamaillard M, Labigne A, Thomas G, Philpott DJ, Sansonetti PJ. Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection. J Biol Chem 2003;278:8869–72.

    Article  PubMed  CAS  Google Scholar 

  5. Mahida YR, Johal S. NF-kappa B may determine whether epithelial cell-microbial interactions in the intestine are hostile or friendly. Clin Exp Immunol 2001;123:347–9.

    Article  PubMed  CAS  Google Scholar 

  6. Elson CO, Cong Y, Brandwein S, Weaver CT, McCabe RP, Mahler M, Sundberg JP, Leiter EH. Experimental models to study molecular mechanisms underlying intestinal inflammation. Ann N Y Acad Sci 1998;859:85–95.

    Article  PubMed  CAS  Google Scholar 

  7. D’Haens GR, Geboes K, Peeters M, Baert F, Penninckx F, Rutgeerts P. Early lesions of recurrent Crohn’s disease caused by infusion of intestinal contents in excluded ileum. Gastroenterology 1998;114:262–7.

    Article  PubMed  CAS  Google Scholar 

  8. Marteau P, Lepage P, Mangin I, Suau A, Dore J, Pochart P, Seksik P. Review article: gut flora and inflammatory bowel disease. Aliment Pharmacol Ther 2004;20Suppl 4:18–23.

    Article  PubMed  Google Scholar 

  9. Duchmann R, May E, Heike M, Knolle P, Neurath M, Meyer zum Buschenfelde KH. T cell specificity and cross reactivity towards enterobacteria, bacteroides, bifidobacterium, and antigens from resident intestinal flora in humans. Gut 1999;44:812–18.

    Article  PubMed  CAS  Google Scholar 

  10. Marteau P, Seksik P, Lepage P, Dore J. Cellular and physiological effects of probiotics and prebiotics. Mini Rev Med Chem 2004;4:889–96.

    PubMed  CAS  Google Scholar 

  11. Akira S, Hemmi H. TLR Signalling and the function of dendritic cells. Chem Immunol Allergy 2005;86:120–35.

    PubMed  Google Scholar 

  12. Cario E, Podolsky DK. Differential alteration in intestinal epithelial cell expression of toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease. Infect Immun 2000;68:7010–17.

    Article  PubMed  CAS  Google Scholar 

  13. Shanahan F. The host-microbe interface within the gut. Best Pract Res Clin Gastroenterol 2002;16:915–31.

    Article  PubMed  Google Scholar 

  14. Gasche C, Scholmerich J, Brynskov J, D’Haens G, Hanauer SB, Irvine EJ, Jewell DP, Rachmilewitz D, Sachar DB, Sandborn WJ, Sutherland LR. A simple classification of Crohn’s disease: report of the Working Party for the World Congresses of Gastroenterology, Vienna 1998. Inflamm Bowel Dis 2000;6:8–15.

    Article  PubMed  CAS  Google Scholar 

  15. Rutgeerts PJ. Conventional treatment of Crohn’s disease: objectives and outcomes. Inflamm Bowel Dis 2001;7Suppl 1:S2–S8.

    PubMed  Google Scholar 

  16. Cosnes J, Nion-Larmurier I, Beaugerie L, Afchain P, Tiret E, Gendre JP. Impact of the increasing use of immunosuppressants in Crohn’s disease on the need for intestinal surgery. Gut 2005;54:237–41.

    Article  PubMed  CAS  Google Scholar 

  17. Jess T, Winther KV, Munkholm P, Langholz E, Binder V. Mortality and causes of death in Crohn’s disease: follow-up of a population-based cohort in Copenhagen County, Denmark. Gastroenterology 2002;122:1808–14.

    Article  PubMed  Google Scholar 

  18. Hughes LE. Clinical classification of perianal Crohn’s disease. Dis Colon Rectum 1992;35:928–32.

    Article  PubMed  CAS  Google Scholar 

  19. Linares L, Moreira LF, Andrews H, Allan RN, Alexander-Williams J, Keighley MR. Natural history and treatment of anorectal strictures complicating Crohn’s disease. Br J Surg 1988;75:653–5.

    PubMed  CAS  Google Scholar 

  20. Faucheron JL, Saint-Marc O, Guibert L, Parc R. Long-term seton drainage for high anal fistulas in Crohn’s disease — a sphincter-saving operation? Dis Colon Rectum 1996;39:208–11.

    Article  PubMed  CAS  Google Scholar 

  21. Scott NA, Nair A, Hughes LE. Anovaginal and rectovaginal fistula in patients with Crohn’s disease. Br J Surg 1992;79:1379–80.

    PubMed  CAS  Google Scholar 

  22. Joseph M, Hewett PJ, Hill H. The use of setons in the management of complex enterocutaneous fistulae of the abdominal wall. Aust N Z J Surg 1994;64:628–9.

    PubMed  CAS  Google Scholar 

  23. Williams JG, MacLeod CA, Rothenberger DA, Goldberg SM. Seton treatment of high anal fistulae. Br J Surg 1991;78:1159–61.

    PubMed  CAS  Google Scholar 

  24. Jeshion WC, Larsen KL, Jawad AF, Piccoli DA, Verma R, Maller ES, Baldassano RN. Azathioprine and 6-mercaptopurine for the treatment of perianal Crohn’s disease in children. J Clin Gastroenterol 2000;30:294–8.

    Article  PubMed  CAS  Google Scholar 

  25. Korelitz BI, Present DH. Favorable effect of 6-mercaptopurine on fistulae of Crohn’s disease. Dig Dis Sci 1985;30:58–64.

    Article  PubMed  CAS  Google Scholar 

  26. Lecomte T, Contou JF, Beaugerie L, Carbonnel F, Cattan S, Gendre JP, Cosnes J. Predictive factors of response of perianal Crohn’s disease to azathioprine or 6-mercaptopurine. Dis Colon Rectum 2003;46:1469–75.

    Article  PubMed  Google Scholar 

  27. Present DH, Rutgeerts P, Targan S, Hanauer SB, Mayer L, van Hogezand RA, Podolsky DK, Sands BE, Braakman T, DeWoody KL, Schaible TF, van Deventer SJ. Infliximab for the treatment of fistulas in patients with Crohn’s disease. N Engl J Med 1999;340:1398–405.

    Article  PubMed  CAS  Google Scholar 

  28. Brown SC, Kazzazi N, Lord PH. Surgical treatment of perineal hidradenitis suppurativa with special reference to recognition of the perianal form. Br J Surg 1986;73:978–80.

    PubMed  CAS  Google Scholar 

  29. Culp CE. Chronic hidradenitis suppurativa of the anal canal. A surgical skin disease. Dis Colon Rectum 1983;26:669–76.

    PubMed  CAS  Google Scholar 

  30. Attanoos RL, Appleton MA, Hughes LE, Ansell ID, Douglas-Jones AG, Williams GT. Granulomatous hidradenitis suppurativa and cutaneous Crohn’s disease. Histopathology 1993;23:111–15.

    PubMed  CAS  Google Scholar 

  31. Burrows NP, Jones RR. Crohn’s disease in association with hidradenitis suppurativa. Br J Dermatol 1992;126:523.

    Article  PubMed  CAS  Google Scholar 

  32. Ostlere LS, Langtry JA, Mortimer PS, Staughton RC. Hidradenitis suppurativa in Crohn’s disease. Br J Dermatol 1991;125:384–6.

    Article  PubMed  CAS  Google Scholar 

  33. Roy MK, Appleton MA, Delicata RJ, Sharma AK, Williams GT, Carey PD. Probable association between hidradenitis suppurativa and Crohn’s disease: significance of epithelioid granuloma. Br J Surg 1997;84:375–6.

    Article  PubMed  CAS  Google Scholar 

  34. Church JM, Fazio VW, Lavery IC, Oakley JR, Milsom JW. The differential diagnosis and comorbidity of hidradenitis suppurativa and perianal Crohn’s disease. Int J Colorectal Dis 1993;8:117–19.

    Article  PubMed  CAS  Google Scholar 

  35. Gower-Rousseau C, Maunoury V, Colombel JF, Coulom P, Piette F, Cortot A, Paris JC. Hidradenitis suppurativa and Crohn’s disease in two families: a significant association? Am J Gastroenterol 1992;87:928.

    PubMed  CAS  Google Scholar 

  36. Sheldon DG, Sawchuk LL, Kozarek RA, Thirlby RC. Twenty cases of peristomal pyoderma gangrenosum: diagnostic implications and management. Arch Surg 2000;135:564–8;discussion 568–9.

    Article  PubMed  CAS  Google Scholar 

  37. Martinez F, Nos P, Benlloch S, Ponce J. Hidradenitis suppurativa and Crohn’s disease: response to treatment with infliximab. Inflamm Bowel Dis 2001;7:323–6.

    Article  PubMed  CAS  Google Scholar 

  38. Katsanos KH, Christodoulou DK, Tsianos EV. Axillary hidradenitis suppurativa successfully treated with infliximab in a Crohn’s disease patient. Am J Gastroenterol 2002;97:2155–6.

    Article  PubMed  Google Scholar 

  39. Bocchini SF, Habr-Gama A, Kiss DR, Imperiale AR, Araujo SE. Gluteal and perianal hidradenitis suppurativa: surgical treatment by wide excision. Dis Colon Rectum 2003;46:944–9.

    Article  PubMed  Google Scholar 

  40. Roussomoustakaki M, Dimoulios P, Chatzicostas C, Kritikos HD, Romanos J, Panayiotides JG, Kouroumalis EA. Hidradenitis suppurativa associated with Crohn’s disease and spondyloarthropathy: response to anti-TNF therapy. J Gastroenterol 2003;38:1000–4.

    Article  PubMed  Google Scholar 

  41. Gupta AK, Skinner AR. A review of the use of infliximab to manage cutaneous dermatoses. J Cutan Med Surg 2004;8:77–89.

    PubMed  Google Scholar 

  42. Rosi YL, Lowe L, Kang S. Treatment of hidradenitis suppurativa with infliximab in a patient with Crohn’s disease. J Dermatolog Treat 2005;16:58–61.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2006 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Seksik, P., Contou, JF., Cosnes, A., Cosnes, J. (2006). Hidradenitis Suppurativa and Crohn’s Disease. In: Jemec, G.B.E., Revuz, J., Leyden, J.J. (eds) Hidradenitis Suppurativa. Springer, Berlin, Heidelberg . https://doi.org/10.1007/978-3-540-33101-8_7

Download citation

  • DOI: https://doi.org/10.1007/978-3-540-33101-8_7

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-33100-1

  • Online ISBN: 978-3-540-33101-8

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics