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Management der In-situ-Karzinome

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Management des Mammakarzinoms

Part of the book series: Onkologie aktuell ((ONKAKTUELL))

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Literatur

  • Badve S, A’Hern RP, Ward AM et al. (1998) Prediction of local recurrence of ductal carcinoma in situ of the breast using five histological classifications: A comparative study with long follow-up. Human Pathol 29: 915–923

    Article  CAS  Google Scholar 

  • Bobrow LG, Happerfield LC, Gregory WM, Springall RD, Millis RR (1994) The classification of ductal carcinoma in situ and its association with biological markers. Sem Diagn Pathol 11:199–207

    CAS  Google Scholar 

  • Böcker W, Bier B, Freytag G et al. (1992) An immunohistochemical study of the breast using antibodies to basal and luminal keratins, alpha smooth muscle actin, vimentin, collagen IV and laminin. Part II: epitheliosis and ductal carcinoma in situ. Virchows Arch A Pathol Anat 421: 323–330

    Article  Google Scholar 

  • Böcker W, Moll R, Dervan P, Bürger H et al. (2002) Usual ductal hyperplasia of the breast is a committed stem (progenitor) cell lesion distinct from atypical ductal hyperplasia and ductal carcinoma in situ. J Pathol 198: 458–467

    Article  Google Scholar 

  • Boyages J, Delaney G, Taylor R (1999) Predictors of local recurrence after treatment of ductal carcinoma in situ. A meta-analysis. Cancer 85: 616–628

    Article  PubMed  CAS  Google Scholar 

  • Buerger H, Otterbach F, Simon R et al. (1999a) Comparative genomic hybridization of ductal carcinoma in situ of the breast-evidence of multiple genetic pathways. J Path 187: 396–402

    Article  PubMed  CAS  Google Scholar 

  • Buerger H, Otterbach F, Simon R et al. (1999b) Different genetic pathways in the evolution of invasive breast cancer are associated with distinct morphological subtypes. J Path 189: 521–526

    Article  PubMed  CAS  Google Scholar 

  • Burstein HJ, Polyak K, Wong JS, Lester SC, Kaelin CM (2004) Ductal carcinoma in situ of the breast. N Engl J Med 350: 1430–1441

    Article  PubMed  CAS  Google Scholar 

  • Chen T, Sahin A, Aldaz CM (1996) Deletion map of chromosome 16q in ductal carcinoma in situ of the breast: refining a putative tumor suppressor gene region. Cancer Res 56: 5605–5609

    PubMed  CAS  Google Scholar 

  • Claus EB, Stowe M, Carter D, Holford T (2003) The risk of a contralateral breast cancer among women diagnosed with ductal and lobular breast carcinoma in situ: data from the Connecticut Tumor Registry. Breast 12: 451–456

    Article  PubMed  Google Scholar 

  • De Potter CR, Schelfhout AM, Verbeeck P et al. (1995) HER-2/neu over-expression correlates with extent of disease in large cell ductal carcinoma in situ of the breast. Human Pathol 26: 601–606

    Article  Google Scholar 

  • European Commission Working Group on Breast Screening Pathology: Sloane JP, Amendoeira I, Apostolikas N et al. (1998) Consistency achieved by 23 European pathologists in categorizing ductal carcinoma in situ of the breast using five classifications. Human Pathol 29: 1056–1062

    CAS  Google Scholar 

  • European Commission Working Group on Breast Screening Pathology: Sloane JP, Amendoeira I, Apostolikas N et al. (1999) Consistency achieved by 23 European pathologists from 12 countries in diagnosing breast disease and reporting prognostic features of carcinoma. Virchows Arch 434: 3–10

    Article  PubMed  CAS  Google Scholar 

  • Faverly DRG, Burgers L, Bult P, Holland R (1994) Three-dimensional imaging of mammary ductal carcinoma in situ: Clinical implications. Sem Diagn Pathol 11: 193–198

    CAS  Google Scholar 

  • Fisher ER, Sass R, Fisher B et al. (1986) Pathologic findings from the National Surgical Adjuvant Breast Project (Protocol 6): Intraductal carcinoma (DCIS). Cancer 57: 197–208

    Article  PubMed  CAS  Google Scholar 

  • Fisher ER, Costantino J, Fisher B, Palekar AS, Redmond C, Mamounas E (1995) Pathologic findings from the National Surgical Adjuvant Breast Cancer Project (NSABP) Protocol B-17. Cancer 75:1310–1319

    Article  PubMed  CAS  Google Scholar 

  • Fisher ER, Costantino J, Fisher B, Palekar AS, Paik SM, Suarez CM, Wolmark N (1996) Pathologic findings from the National Surgical Adjuvant Breast Project (NSABP) Protocol B-17. Cancer 78:1403–1416

    Article  PubMed  CAS  Google Scholar 

  • Fisher ER, Land SR, Fisher B, Mamounas E, Gilarski L, Wolmark L (2004) Pathologic findings from the National Surgical Adjuvant Breast and Bowel Project. Twelve-year observations concerning lobular carcinoma in situ. Cancer 100: 238–244

    Article  PubMed  Google Scholar 

  • Fisher B, Costantino J, Redmond C et al. (1993) Lumpectomy compared with lumpectomy and radiation therapy for the treatment of intraductal breast cancer. N Engl J Med 328: 1581–1586

    Article  PubMed  CAS  Google Scholar 

  • Fisher B, Dignam J, Wolmark N, Mamounas E, Costantine J, Poller W et al. (1998) Lumpectomy and radiation therapy for the treatment of intraductal breast cancer: Findings from the National Surgical Adjuvant Breast and Bowel Project B-17. J Clin Oncol 16: 441–52

    PubMed  CAS  Google Scholar 

  • Fisher B, Land S, Mamounas E, Dignam J, Fisher ER, Wolmark N (2001) Prevention of invasive breast cancer in women with ductal carcinoma in situ: an update of the National Surgical Adjuvant Breast and Bowel Project experience. Semin Oncol 28: 400–418

    Article  PubMed  CAS  Google Scholar 

  • Foote FW Jr, Stewart FW (1941) Lobular carcinoma in situ: a rare form of mammary cancer. Am J Pathol 17: 491–496

    Google Scholar 

  • Fuji H, Szumel R, Marsh C, Zhou W, Gabrielson E (1996) Genetic progression, histological grade and allelic loss in ductal carcinoma in situ of the breast. Cancer Res 56: 5260–5265

    Google Scholar 

  • Gould EW, Robinson PG (1992) The pathologist’s examination of the »umpectomy« — the pathologist’s view of surgical margins. Sem Surg Oncol 8: 129–135

    CAS  Google Scholar 

  • Haagensen CD, Lane N, Bodian C (1983) Coexisting lobular neoplasia and carcinoma of the breast. Cancer 51: 1468–1482

    Article  PubMed  CAS  Google Scholar 

  • Harvey JM, Sterrett GF, Frost FA (2002) Atypical ductal hyperplasia of uncertain significance in core biopsies from mammographically detected lesions: correlation with excision diagnosis. Pathology 34:410–416

    Article  PubMed  Google Scholar 

  • Holland R, Hendriks JHCL (1994) Microcalcifications associated with ductal carcinoma in situ: mammographic-pathologic correlation. Sem Diagn Pathol 11: 181–192

    CAS  Google Scholar 

  • Houghton J, George WD, Cuzick J, Duggan C, Fentiman IS, Spittle M (2003) Radiotherapy and Tamoxifen in women with completely excised ductal carcinoma in situ of the breast in the UK, Australia and New Zealand: randomised controlled trial. Lancet 362:95–102

    Article  PubMed  Google Scholar 

  • Hwang ES, Nyante SJ, Chen YY, Moore D, DeVries S, Korkola JE, Esserman LJ, Waldman FM (2004) Clonality of lobular carcinoma in situ and synchronous invasive lobular carcinoma. Cancer 100:2562–2572

    Article  PubMed  Google Scholar 

  • Julien J-P, Bijker N, Fentiman IS, Peterse JL et al. (2000) Radiotherapy in breast-conserving treatment for ductal carcinoma in situ: first results of the EORTC randomized phase III trial 10853. Lancet 355:528–533

    Article  PubMed  CAS  Google Scholar 

  • Kanthan R, Xiang J, Magliocco AM (2000) p53, ErbB2, and TAG-72 expression in the spectrum of ductal carcinoma in situ of the breast classified by the Van Nuys system. Arch Pathol Lab Med 123: 234–239

    Google Scholar 

  • Lagios MD (1990) Duct carcinoma in situ: pathology and treatment. Surg Clin N A 70: 853–871

    CAS  Google Scholar 

  • Lagios MD (1995) Ductal carcinoma in situ: controversies in diagnosis, biology, and treatment. Breast J 1: 68–78

    Google Scholar 

  • Lagios MD, Margolin FR, Westdahl PR, Rose MR (1989) Mammographically detected duct carcinoma in situ: Frequency of local recurrence following tylectomy and prognostic effect of nuclear grade on local recurrence. Cancer 63: 618–624

    Article  PubMed  CAS  Google Scholar 

  • Lakhani SR (1999) The transition from hyperplasia to invasive carcinoma of the breast. J Pathol 187: 272–278

    Article  PubMed  CAS  Google Scholar 

  • Lakhani SR, Collins N, Stratton MR, Sloane JP (1995) Atypical ductal hyperplasia of the breast: clonal proliferation with loss of heterozygosity on chromosomes 16q and 17p. J Clin Pathol 48: 611–615

    PubMed  CAS  Google Scholar 

  • Micale MA, Visscher DW, Gulino SE, Wolman SR (1995) Chromosomal aneuploidy in proliferative breast disease. Human Pathol 25:29–35

    Article  Google Scholar 

  • Moinfar F, Man YG, Lininger RA, Bodian C, Tavassoli FA (1999) Use of keratin 34ßE12 as an adjunct in the diagnosis of mammary intraepithelial neoplasia-ductal type — benign and malignant intraductal proliferations. Am J Surg Pathol 23: 1048–1058

    Article  PubMed  CAS  Google Scholar 

  • Moore E, Magee H, Coyne J, Gorey T, Dervan PA (1999) Widespread chromosomal abnormalites in high-grade ductal carcinoma in situ of the breast. Comparative genomic hybridization study of pure high-grade DCIS. J Path 187: 403–409

    Article  PubMed  CAS  Google Scholar 

  • Page DL (1982) Intraductal carcinoma of the breast: Follow-up after biopsy only. Cancer 49: 751–758

    Article  PubMed  CAS  Google Scholar 

  • Page DL, Dupont WD, Rogers LW et al. (1995) Continued local recurrence of carcinoma 15–25 years after diagnosis of low grade ductal carcinoma of the breast treated only by biopsy. Cancer 76: 1197–1200

    Article  PubMed  CAS  Google Scholar 

  • Page DL, Schuyler PA, Dupont WD, Jensen RA, Plummer WD, Simpson JF (2003) Atypical lobular hyperplasia as a unilateral predictor of breast cancer risk: a retrospective cohort study. The Lancet 361:125–129

    Article  Google Scholar 

  • Pinder SE und Ellis IO (2003) The diagnosis and management of pre-invasive disease. Ductal carcinoma in situ (DCIS) and atypical ductal hyperplasia (ADH) — current definitions and classifications. Breast Cancer Res 5: 254–257

    Article  PubMed  Google Scholar 

  • Poller DN, Snead D, Roberts EC et al. (1993) Estrogen receptor expression in ductal carcinoma in situ of the breast: Relationship to flow cytometric analysis of DNA and expression of the c-erbB-2 oncoprotein. Br J Cancer 68: 156–161

    PubMed  CAS  Google Scholar 

  • Rosen PP (1980) Coexistent lobular carcinoma in situ and intraductal carcinoma in a single lobular-duct unit. Am J Surg Pathol 4:241–246

    Article  PubMed  CAS  Google Scholar 

  • Rosen PP, Oberman HA (1992) Tumors of the mammary gland. Atlas of tumor pathology, fascicle 7, third series. Armed Forces Institute of Pathology, Washington DC

    Google Scholar 

  • Shoker BS, Sloane JP (1999) DCIS grading schemes and clinical implications. Histopathology 35: 393–400

    Article  PubMed  CAS  Google Scholar 

  • Silverstein MJ, Gierson ED, Colburn WJ et al. (1994) Can intraductal breast carcinoma be excised completely by local excision? Cancer 73: 2985–2989

    Article  PubMed  CAS  Google Scholar 

  • Silverstein MJ, Lagios MD, Craig PH, Waisman JR, Lewinsky BS, Colburn WJ, Poller DN (1996) A prognostic index for ductal carcinoma in situ of the breast. Cancer 77: 2267–2274

    Article  PubMed  CAS  Google Scholar 

  • Silverstein MJ, Poller DN, Waisman JR et al. (1995) Prognostic classification of breast ductal carcinoma in situ. Lancet 345: 1154–1157

    Article  PubMed  CAS  Google Scholar 

  • Silverstein MJ, Rosser RJ, Gierson ED et al. (1987) Axillary lymph node dissection for intraductal breast carcinoma — is it indicated? Cancer 59: 1819–1824

    Article  PubMed  CAS  Google Scholar 

  • Silverstein MJ, Lagios MD, Groshen S et al. (1999) The influence of margin width on local control of ductal carcinoma in situ of the breast. N Engl J Med 340: 1455–1461

    Article  PubMed  CAS  Google Scholar 

  • Silverstein MJ (2003) The University of Southern California/Van Nuys prognostic index for ductal carcinoma in situ of the breast. Am J Surg 186: 337–343

    Article  PubMed  Google Scholar 

  • Silverstein MJ and Buchanan C (2003) Ductal carcinoma in situ: USC/ Van Nuys Prognostic Index and the impact of margin status. Breast 12: 457–471

    Article  PubMed  Google Scholar 

  • Susnik B, Worth A, Palcic B, Poulin N, LeRiche J (1995) Differences in quantitative nuclear features between ductal carcinoma in situ (DCIS) with and without accompanying invasive carcinoma in the surrounding breast. Anal Cell Pathol 8: 39–52

    PubMed  CAS  Google Scholar 

  • Tulusan AH, Egger H, Schneider ML, Willgeroth F (1982) Lobular carcinoma in situ and its relation to breast cancer. Arch Gynecol 231:219–226

    Article  PubMed  CAS  Google Scholar 

  • Zafrani B, Contesso G, Eusebi V, Holland R, Millis RR, Peterse JL (1995) Guidelines for the pathological management of mammographically detected breast lesions. Breast 4: 52–56

    Article  Google Scholar 

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Authors and Affiliations

  1. Dept. Histopathology, Birmingham Women’s Hospital, Metchley Park Road, Edgbaston, Birmingham West Midlands, B 15 2TG, UK

    Priv.-Doz. Dr. med. Margarete Mitze

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  1. Priv.-Doz. Dr. med. Margarete Mitze
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© 2006 Springer Medizin Verlag Heidelberg

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Mitze, M. (2006). Management der In-situ-Karzinome. In: Management des Mammakarzinoms. Onkologie aktuell. Springer, Berlin, Heidelberg . https://doi.org/10.1007/978-3-540-31748-7_22

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  • DOI: https://doi.org/10.1007/978-3-540-31748-7_22

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-31747-0

  • Online ISBN: 978-3-540-31748-7

  • eBook Packages: Medicine (German Language)

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