Abstract
Epidemiology. Maculopapular exanthems are the most common adverse drug reactions, along with urticaria. Almost every medication on the market has caused at least one maculopapular exanthem.
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Bibliography
Books
Bork K (1988) Cutaneous side effects of drugs. Saunders, Philadelphia
Bruinsma W (2000) Side effects in dermatology, 7th ed. Intermed Medical Publishers, Amsterdam
Litt JZ (2004) Litt’s pocketbook of drug eruptions and interactions. 3rd ed. Parthenon, Boca Raton
Litt JZ (2007) Litts drug eruption reference manual including drug interactions. 13th ed. Informa Healthcare, New York
Zürcher K, Krebs A (1992) Cutaneous drug reactions, 2nd ed. Karger, Basel
Papers
Agostoni A, Cicardi M (2001) Drug-induced angioedema without urticaria. Drug Safety 24:599–606
Alley E, Green R, Schuchter L (2002) Cutaneous toxicities of cancer therapy. Curr Opin Oncol 14:212–216
Autier J, Escudier B, Wechsler J et al (2008) Prospective study of the cutaneous adverse effects of sorafenib, a novel multikinase inhibitor. Arch Dermatol 144:886–892
Baack BR, Burgdorf WH (1991) Chemotherapy-induced acral erythema. J Am Acad Dermatol 24:457–461
Bastuji-Garin S, Joly P, Picard-Dahan C et al (1993) Drugs associated with bullous pemphigoid. A case-control study. Arch Dermatol 132:272–276
Bhattacharjee P, Glusac EJ (2004) Early histopathologic changes in purple glove syndrome. J Cutan Pathol 31:513–515
Budach W, Bolke E, Homey B (2007) Severe cutaneous reaction during radiation therapy with concurrent cetuximab. N Engl J Med 357:514–515
Callen JP (2001) Drug-induced cutaneous lupus erythematosus, a distinct syndrome that is frequently unrecognized. J Am Acad Dermatol 45:315–316
Carroll MC, Yueng-Yue KA, Esterly NB et al (2001) Drug-induced hypersensitivity syndrome in pediatric patients. Pediatrics 108:485–492
Comp PC (1993) Coumarin-induced skin necrosis. Incidence, mechanisms, management and avoidance. Drug Safety 8:128–135
Dalmau J, Pimentel CL, Puig L et al (2005) Cutaneous necrosis after injection of polyethylene glycol-modified interferon alfa. J Am Acad Dermatol 53:62–66
DeWitt CA, Siroy AE, Stone SP (2007) Acneiform eruptions associated with epidermal growth factor receptor-targeted chemotherapy. J Am Acad Dermatol 56:500–505
Goldfeder KL, Levin JM, Katz KA et al (2007) Ultraviolet recall reaction after total body irradiation, etoposide, and methotrexate therapy. J Am Acad Dermatol 56:494–499
Grattan CEH (2004) Aspirin sensitivity and urticaria. Clin Exp Dermatol 28:123–127
Heidary N, Naik H, Burgin S (2008) Chemotherapeutic agents and the skin: An update. J Am Acad Dermatol 58:545–570
Justiniano H, Berlingeri-Ramos AC, Sanchez JL (2008) Pattern analysis of drug-induced skin diseases. Am J Dermatopathol 30:352–369
Le Goff P, Saraux A (1999) Drug-induced lupus. Rev Rhum Engl Ed 66:40–45
Lotti T, Ghersetich I, Comacchi C et al (1998) Cutaneous small-vessel vasculitis. J Am Acad Dermatol 39:667–687
Mahhob A, Haroon TS (1998) Drugs causing fixed eruptions: a study of 450 cases. Int J Dermatol 37:833–838
Nettis E, Marcandrea M, Di Maggio G et al (2001) Retrospective analysis of drug-induced urticaria and angioedema: a survey of 2287 patients. Immunopharmacol Immunotoxicol 23:585–595
Palareti G, Leali N, Coccheri S et al (1996) Bleeding complications of oral anticoagulant treatment: an inception-cohort, prospective collaborative study (ISCOAT). Lancet 348:423–428
Patel DD, Goldberg RM (2006) Cetuximab-associated infusion reactions: pathology and management. Oncology 20:1373–1382
Payne AS, James WD, Weiss RB (2006) Dermatologic toxicity of chemotherapeutic agents. Semin Oncol 33:86–97
Pichichero ME, Casey JR (2007) Safe use of selected cephalosporins in penicillin-allergic patients: a meta-analysis. Otolaryngol Head Neck Surg 136:340–347
Piraccini BM, Tosti A (1999) Drug-induced nail disorders: incidence, management and prognosis. Drug Safety 21:187–201
Remlinger KA (2003) Cutaneous reactions to chemotherapy drugs: the art of consultation. Arch Dermatol 139:77–81
Renn CN, Straff W, Dorfmüller A et al (2003) Amoxicillin-induced exanthema in young adults with infectious mononucleosis: demonstration of drug-specific lymphocyte reactivity. Br J Dermatol 147:1166–1167
Rubin RL (1999) Etiology and mechanisms of drug-induced lupus. Curr Opin Rheumatol 11:357–363
Shiohara T, Mizukawa Y, Teraki Y (2002) Pathophysiology of fixed drug eruption: the role of skin-resident T cells. Curr Opin Allergy Clin Immunol 2:317–323
Shipley D, Ormerod AD (2001) Drug-induced urticaria. Recognition and treatment. Am J Clin Dermatol 2:151–158
Susser WS, Whitaker-Worth DL, Grant-Kels JM (1999) Mucocutaneous reactions to chemotherapy. J Am Acad Dermatol 40:367–398
Tan EK, Grattan CE (2004) Drug-induced urticaria. Expert Opin Drug Saf 3:471–484
Thorisdottir K, Tomecki KJ, Bergfeld WF et al (1993) Neutrophilic eccrine hidradenitis. J Am Acad Dermatol 28:775–777
Tosti A, Misciali C, Piraccine BM et al (1994) Drug-induced hair loss and hair growth. Incidence, management and avoidance. Drug Safety 10: 310–317
Tosti A, Pazzaglia M (2007) Drug reactions affecting hair: diagnosis. Dermatol Clin 25:223–231
Warner KK, Visconti JA, Tschampel MM (2000) Angiotensin II receptor blockers in patients with ACE inhibitor-induced angioedema. Ann Pharmacother 34:526–528
de Weck AL, Gamboa PM, Esparza R et al (2006) Hypersensitivity to aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs). Curr Pharm Des 12:3347–3358
Wong BB, Keith PK, Waserman S (2006) Clinical history as a predictor of penicillin skin test outcome. Ann Allergy Asthma Immunol 97:169–174
Yawalkar N, Pichler WJ (2001) Pathogenesis of drug-induced exanthema. Int Arch Allergy Immunol 124:336–338
Cutaneous Signs of Drug Abuse
Binswanger IA, Kral AH, Bluthenthal RN et al (2000) High prevalence of abscesses and cellulitis among community-recruited injection drug users in San Francisco. Clin Infect Dis 30:579–581
Brewer JD, Meves A, Bostwick JM et al (2008) Cocaine abuse: Dermatologic manifestations and therapeutic approaches. J Am Acad Dermatol 59:483–487
Burnett JW (1992) Drug abuse. Cutis 49:307–308
Del Giudice P (2004) Cutaneous complications of intravenous drug abuse. Br J Dermatol 150:1–10
Del Giudice P, Durant J, Dellamonica P (2006) Hand edema and acrocyanosis: puffy hand syndrome. Arch Dermatol 142:1084–1085
Feuillet L, Mallet S, Spadari M (2006) Twin girls with neurocutaneous symptoms caused by mothball intoxication. N Engl J Med 355:423–424
Gordon RJ, Lowy FD (2005) Bacterial infections in drug users. N Engl J Med 353:1945–1954
Kimura AC, Higa JI, Levin RM et al (2004) Outbreak of necrotizing fasciitis due to Clostridium sordellii among black-tar heroin users. Clin Infect Dis 38:e87–91
Lu LK, High WA (2007) Acute generalized exanthematous pustulosis caused by illicit street drugs? Arch Dermatol 143:430–431
Passaro DJ, Werner SB, McGee J, Mac Kenzie WR, Vugia DJ. (1998) Wound botulism associated with black tar heroin among injecting drug users. JAMA 279:859–863
Wiesner O, Russell KA, Lee AS et al (2004) Antineutrophil cytoplasmic antibodies reacting with human neutrophil elastase as a diagnostic marker for cocaine-induced midline destructive lesions but not autoimmune vasculitis. Arthritis Rheum 50:2954–2965
Wollina U, Kammler HJ, Hesselbarth N et al (1998) Ecstasy pimples — a new facial dermatosis. Dermatology 197:171–173
Classic Papers
Andersen KE, Hjorth N, Menne T (1984) The baboon syndrome: Systemicallyinduced allergic contact dermatitis. Contact Dermatitis 10:97–100
Burgdorf WHC, Gilmore WA, Ganick RG (1982) Peculiar acral erythema secondary to high-dose chemotherapy for acute myelogenous leukemia. Ann Intern Med 97:61–62
Freudenthal W (1924) Lokales embolisches Bismogenol-Exanthem. Arch Dermatol Syph (German) 147:155–160
Hoigné R, Schoch K (1959) Anaphylaktischer Schock und akute, nicht allergische Reaktionen nach Procain-Penicillin. Schweiz Med Wochenschr 89:1350–1356
Nicolau S (1925) Dermate livédoide et grangréneuse de la fesse, consécutive au injections intra-musculaires dans la syphilis. A propos d’un cas d’embolie artérielle bismuthique. Ann Mal Vénér 20:321–329
Zuehlke RL (1974) Erythematous eruption of the palms and soles associated with mitotane therapy. Dermatologica 148:90–92
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Bork, K. (2009). Cutaneous Adverse Drug Reactions. In: Burgdorf, W.H., Plewig, G., Wolff, H.H., Landthaler, M., Braun-Falco, O. (eds) Braun-Falco’s Dermatology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-29316-3_33
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DOI: https://doi.org/10.1007/978-3-540-29316-3_33
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-29312-5
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