Rechargeable Glucose Biosensors

Abstract

There are several studies by numerous investigators in the area of glucose sensing, aimed at fulfilling the need for an implantable glucose sensor to close the loop for an insulin pump, and obtain a complete artificial pancreas^1–3 However, a continuously functioning implantable glucose sensor with long-term stability has not yet been achieved. Research is being carried out on several types of potentially implantable glucose sensors: electrochemical sensors based on direct electrooxidation of glucose on noble metal electrodes, and biosensors combining the selectivity of substrate-specific (in this case glucose-specific) enzymes with the versatility and simplicity of electrochemical electrode systems.