Abstract
The pentose phosphate cycle has been presented as a paradigm of optimization in the design of metabolic pathways. The hypothesis of simplicity, i.e. the tendency to the least number of both steps and carbons involved in every intermediate, seems to have played a prominent role in its evolution. In fact, the number of steps and carbons of the intermediates affect the values of important characteristics of the system, such as the total flux of the pathway and its transition time.
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© 1996 Friedr. Vieweg & Sohn Verlagsgesellschaft mbH, Braunschweig/Wiesbaden
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Montero, F., Nuño, J.C., Andrade, M.A., Pérez-Iratxeta, C., Morán, F., Meléndez-Hevia, E. (1996). The Role of Natural Selection and Evolution in the Game of the Pentose Phosphate Cycle. In: Ghista, D.N. (eds) Biomedical and Life Physics. Vieweg+Teubner Verlag. https://doi.org/10.1007/978-3-322-85017-1_14
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DOI: https://doi.org/10.1007/978-3-322-85017-1_14
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