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Solid Lipid Nanoparticles: A Modern Approach for the Treatment of Neurodegenerative Diseases

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Book cover Nanotechnology: Applications in Energy, Drug and Food

Abstract

Targeting drugs to the Central nervous system (CNS) for any CNS related disorders has been a herculean task mainly due to the inability of drugs to cross the blood-brain barrier and blood-cerebrospinal fluid barrier. Nanotechnology has been widely adopted to overcome this shortcoming. Solid lipid nanoparticles have been suggested as successful among the different Nano Drug Delivery systems. The increased chances of traversing the blood brain barrier by the lipid components of solid lipid nanoparticles is notable in addition to the other benefits offered by nanoparticles. The current chapter discusses the application of solid lipid nanoparticles in neurodegenerative diseases.

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Author information

Authors and Affiliations

  1. Formulation Development Laboratory, Pharmaceutical R&D, Piramal Enterprises Limited, Mumbai, India

    Anisha A. D’Souza

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  1. Anisha A. D’Souza
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Editors and Affiliations

  1. Biotechnology Research Institute, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia

    Shafiquzzaman Siddiquee

  2. Material and Mineral Research Unit (MMRU), Faculty of Engineering, Universiti Malaysia Sabah, Jalan UMS, Kota Kinabalu, Sabah, Malaysia

    Gan Jet Hong Melvin

  3. Faculty of Engineering, Energy Research Unit (ERU), Universiti Malaysia, Kota Kinabalu, Sabah, Malaysia

    Md. Mizanur Rahman

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D’Souza, A.A. (2019). Solid Lipid Nanoparticles: A Modern Approach for the Treatment of Neurodegenerative Diseases. In: Siddiquee, S., Melvin, G., Rahman, M. (eds) Nanotechnology: Applications in Energy, Drug and Food. Springer, Cham. https://doi.org/10.1007/978-3-319-99602-8_9

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