Abstract
Nuclear medicine deals with diagnostics and therapy using radioactive isotopes emitting beta or gamma radiation. Radiopharmaceuticals are pharmaceuticals containing radioactive isotope as tracer and a ligand, i.e. a molecule, chemical compound or cell (e.g. granulocyte) that has an affinity towards a tissue or organ. When administered to a patient, radioactivity emitted by a radiopharmaceutical is being registered. As various tissues and organs differently accumulate this tracer, changes in radioisotope intake are detectable, especially when tissue metabolism rate is disturbed by a pathological process.
Registration of radiation can be performed by means of a single static gamma camera (also known as a scintillation camera), one or more rotating gamma cameras or multiheaded gamma cameras. Depending on the type of registration device, the imaging methods are divided into scintigraphy, single-photon emission computed tomography (SPECT) and positron emission tomography (PET).
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Różyło-Kalinowska, I. (2019). Nuclear Medicine in TMJ Imaging. In: Rozylo-Kalinowska, I., Orhan, K. (eds) Imaging of the Temporomandibular Joint. Springer, Cham. https://doi.org/10.1007/978-3-319-99468-0_12
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