Skip to main content
Book cover

Pain pp 315–319Cite as

Marijuana

  • Chapter
  • First Online:
  • 252 Accesses

Abstract

Cannabinoids are derived from the cannabis plant. Their actions for pain control are exerted on two receptors that are part of the endocannabinoid system, CB1 and CB2. Multiple trials have shown positive outcomes in pain control, particularly in neuropathic pain, for several cannabinoid products. Currently, cannabis is still listed as a Schedule I drug, a drug that has no medicinal use; however, several states have implemented medical marijuana laws allowing use in several disease states. More evidence is needed to establish its efficacy and risk profiles.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   149.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD   199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

References

  1. Aggarwal SK. Cannabinergic pain medicine: a concise clinical primer and survey of randomized-controlled trial results. Clin J Pain. 2013;29(2):162–71.

    Article  Google Scholar 

  2. Wolkerstorfer A, Handler N, Buschmann H. New approaches to treating pain. Bioorg Med Chem Lett. 2016;26:1103–19.

    Article  CAS  Google Scholar 

  3. Abrams DI, Couey P, Shade SB, Kelly ME, Benowitz NL. Cannabinoid-opioid interaction in chronic pain. Clin Pharmacol Ther. 2011;90(6):844–51.

    Article  CAS  Google Scholar 

  4. Facts and Comparisons eAnswers. Dronabinol. http://fco.factsandcomparisons.com/lco/action/doc/retrieve/docid/fc_dfc/5549273. Accessed Oct 2017.

  5. Facts and Comparisons eAnswers. Nabilone. http://fco.factsandcomparisons.com/lco/action/doc/retrieve/docid/fc_dfc/5549272. Accessed Oct 2017.

  6. Lynch ME, Campbell F. Cannabinoids for treatment of chronic non-cancer pain; a systematic review of randomized trials. Br J Clin Pharmacol. 2011;72(5):735–44.

    Article  CAS  Google Scholar 

  7. Lynch ME, Ware MA. Cannabinoids for the treatment of chronic non-cancer pain: an updated systematic review of randomized controlled trials. Br J Clin Pharmacol. 2015;10:293–301.

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Greta Nemergut .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Nemergut, G. (2019). Marijuana. In: Abd-Elsayed, A. (eds) Pain. Springer, Cham. https://doi.org/10.1007/978-3-319-99124-5_69

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-99124-5_69

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-99123-8

  • Online ISBN: 978-3-319-99124-5

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics