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Applications of AIE to Molecular Recognition: Why Is It Superior to Unimolecular Recognition?

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Principles and Applications of Aggregation-Induced Emission

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Abstract

Self-assembly has been utilized for the spontaneous formation of nanoarchitectures. Therein, a small change in the molecular structure dramatically alters the resulting macroscopic self-assembly morphologies and the consequent material properties. This macroscopic expression of the small initial difference via self-assembly can be alternatively regarded as precise translation of molecular structural information. In this chapter, we offer a novel molecular recognition concept utilizing self-assembly phenomena. A small difference in guest structures affords distinctly different self-assembly modes of fluorescent (FL) chemosensors and leads to their sensory responses characteristic of the guest structures. Thus, self-assembly has now been utilized as a FL sensory system for molecular recognition, particularly, of biologically important molecules and macromolecules. Through these studies, we wish to demonstrate why the AIE-based recognition is superior to that of unimolecule-based recognition.

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Acknowledgments

This work was supported by the Ministry of Education, Culture, Sports, Science and Technology of Japan, Grant-in-Aid for Scientific Research (C) (Grant Number 17K05848) and for Young Scientists B (Grant Numbers JP25810051 and JP16K17937).

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Authors and Affiliations

  1. Institute for Advanced Study, Kyushu University, Fukuoka, Japan

    Takao Noguchi, Daisuke Yoshihara & Seiji Shinkai

Authors
  1. Takao Noguchi
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  2. Daisuke Yoshihara
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  3. Seiji Shinkai
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Corresponding author

Correspondence to Seiji Shinkai .

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Editors and Affiliations

  1. Institute for NanoScale Science and Technology, College of Science and Engineering, Flinders University, Adelaide, SA, Australia

    Youhong Tang

  2. State Key Laboratory of Luminescent Materials and Devices, Center for Aggregation-Induced Emission, South China University of Technology, Guangzhou, China

    Ben Zhong Tang

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Noguchi, T., Yoshihara, D., Shinkai, S. (2019). Applications of AIE to Molecular Recognition: Why Is It Superior to Unimolecular Recognition?. In: Tang, Y., Tang, B. (eds) Principles and Applications of Aggregation-Induced Emission. Springer, Cham. https://doi.org/10.1007/978-3-319-99037-8_8

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