Abstract
This chapter introduced the subject of iron metabolism, including the regulation of body iron distribution and intestinal iron absorption, followed by an explanation of the pathophysiology of iron depletion. The phases of the development of iron-deficiency anemia and its prevalence in different populations at risk are outlined. The clinical manifestations of iron deficiency and the resulting anemia are reviewed, along with a description of laboratory tests to diagnose the condition. The importance of determining the cause of the patient’s iron deficiency and the approach to treatment is summarized. The final section focused on the anemia of inflammation and its differentiation from iron deficiency.
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22 February 2019
This book was inadvertently published with incorrectedition information in Preface as “The third edition” whereas it should be “The second edition”.
References
Ganz T. Iron deficiency and overload. In: Kaushansky K, Lichtman MA, Prchal JT, et al., editors. Williams hematology. 9th ed. New York: McGraw-Hill; http://accessmedicine.mhmedical.com/content.aspx?bookid=1581§ionid=94304160.
Cogswell ME, Looker AC, Pfeiffer CM, Cook JD, Lacher DA, Beard JL, Lynch SR, Grummer- Strawn LM, et al. Assessment of iron deficiency in US preschool children and nonpregnant females of childbearing age: National Health and Nutrition Examination Survey 2003–2006. Am J Clin Nutr. 2009;89(5):1334–42.
Looker AC, Dallman PR, Carroll MD, Gunter EW, Johnson CL. Prevalence of iron deficiency in the United States. JAMA. 1997;277(12):973–6.
Parkes E. Nutritional management of patients after bariatric surgery. Am J Med Sci. 2006;331(4):207–13.
Murray-Kolb LE, Beard JL. Iron deficiency and child and maternal health. Am J Clin Nutr. 2009;89(3):946S–50S.
Cook JD. Diagnosis and management of iron-deficiency anaemia. Best Pract Res Clin Haematol. 2005;18(2):319–32.
Schrier SL. So you know how to treat iron deficiency anemia. Blood. 2015;126(17):1971.
Hershko C, Camaschella C. How I treat unexplained refractory iron deficiency anemia. Blood. 2014;123(3):326–33.
Auerbach C, Deloughery T. Single-dose intravenous iron for iron deficiency: a new paradigm. Hematol Am Soc Hematol Educ Program. 2016;2016(1):57–66.
Keel SB, Abkowitz JL. The microcytic red cell and the anemia of inflammation. N Engl J Med. 2009;361(19):1904–6.
Rakel RE, Bope ET, editors. Conn’s current therapy 2002. Philadelphia: Saunders; 2002. p. 357.
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McLaren, G.D. (2019). Iron Deficiency. In: Lazarus, H., Schmaier, A. (eds) Concise Guide to Hematology. Springer, Cham. https://doi.org/10.1007/978-3-319-97873-4_5
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DOI: https://doi.org/10.1007/978-3-319-97873-4_5
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