Abstract
The origin of life is a large and active field of research, and one chapter in this book can hardly do it justice. Yet, if we are to make reasonable inferences about the probability of life on other worlds, we must be able to gauge the possibility that living systems could have arisen (or arrived) there in the first place. And that, in turn, depends on our understanding of what the possibilities are for the origin of life anywhere. In an effort to rescue those possibilities from the realm of total speculation, we consider first what we know or infer about the origin of life on Earth, hoping that this singular example can provide some insights into and boundaries upon our thinking about the generic origins of life, wherever they have occurred. Then we use our limited understanding of what may have happened at the dawn of life on Earth, in combination with our definition of life given in Chap. 2, to focus on inferences with regard to the first cellular membranes, the first metabolisms, and the first replication mechanisms. Finally, we will discuss the implications of these insights for the predictability of life elsewhere in the Universe.
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References
Andes-Koback, M. and C.D. Keating. 2011. Complete budding and asymmetric division of primitive model cells to produce daughter vesicles with different interior and membrane compositoions. J. Am. Chem. Soc. 133: 9545-9555.
Ardell, D.H. and G. Sella. 2001. On the evolution of redundancy in genetic codes. J. Molec. Evol. 53: 269-281.
Arrhenius, S. 1903. Die Verbreitung des Lebens im Weltenraum. Umschau 7: 481-485.
Attwater, J., A. Wochner, and P. Holliger. 2013. In-ice evolution of RNA polymerase ribozyme activity. Nature Chem. 5: 1011–1018.
Bada, J.L., and A. Lazcano. 2002a. Miller revealed new ways to study the origins of life. Nature 416: 475.
Bada, J.L., and A. Lazcano. 2002b. Some like it hot, but not the first biomolecules Science 269: 1982-1983.
Bada, J.L. 2004. How life began on Earth: a status report. Earth Planetary Sci. Lett. 226: 1-15.
Baker, B.J., G.W. Tyson, R.I. Webb, et al. 2006. Lineages of acidophilic archaea revealed by community genomic analysis. Science 314: 1933-1935.
Ball, R. and J. Brindley, J. 2015. The life story of hydrogen peroxide II: a periodic pH and thermochemical drive for the RNA world. J. Roy. Soc. Interface 12: 20150366.
Barrell, B.G., A.T. Bankier, and J. Drouin, J. 1979. A different genetic code in human mitochondria. Nature 282: 189-194.
Benner, S.A. 2002. Weird life: chances vs. necessity (alternative biochemistries). In “Weird Life” Planning Session for the Committee on the Origins and Evolution of Life, at Washington, DC, USA.
Bernal, J.D. 1967. The origin of life. World Publ., Cleveland.
Branscomb, E. and M.J. Russell. 2012, Turnstiles and bifurcators: the disequilibrium converting engines that put metabolism on the road. Biochim. Biophys. Acta 1827: 62-78.
Budisa, N. 2005. Engineering the Genetic Code: Expanding the Amino Acid Repertoire for the Design of Novel Proteins. New York, NY USA: John Wiley.
Burton, F.G., R. Lohrmann and L.E. Orgel. 1974. On the possible role of crystals in the origins of life. VII. The adsorption and polymerization of phosphoramidates by montmorillonite clay. J Mol Evol 3: 141-150.
Bhavesh H. Patel, Claudia Percivalle, Dougal J. Ritson, Colm D. Duffy, John D. Sutherland, (2015) Common origins of RNA, protein and lipid precursors in a cyanosulfidic protometabolism. Nature Chemistry 7 (4):301–307
Cairns-Smith, A.G. 1982. Genetic Takeover. Cambridge University Press, London.
Cairns-Smith, A.G. 1985. Seven clues to the origin of life. Cambridge University Press, Cambridge.
Cairns-Smith, A.G., and H. Hartman. 1986. Clay minerals and the origin of life Cambridge University Press, UK.
Calvin, M. 1969. Chemical Evolution: Molecular Evolution Towards the Origin of Living Systems on the Earth and Elsewhere. Oxford University Press, New York.
Carter, C.W. 2015. What RNA world? Why a peptide/RNA partnership merits renewed experimental attention. Life (Basel) 5: 294-320.
Cech, T.R. 1985. Self-splicing RNA: implications for evolution. Int. Rev. Cytol. 93: 3-22.
Chan, S., J. Orenberg and N. Lahav. 1987. Soluble minerals in chemical evolution. II. Characterization of the adsorption of 5’-AMP and 5’-CMP on a variety of soluble mineral salts. Orig. Life Evol. Biosph. 17: 121-134.
Chang, S. 1993. Prebiotic synthesis in planetary environments pp. 259-300 in J.M. Greenberg, C.X. Mendoza-Gomez and V. Pirronello, eds. The Chemistry of Life’s Origins. Kluwer Academic Publishers, Dordrecht.
Chaput, J.C., and J.W. Szostak. 2003. TNA synthesis by DNA polymerases. J. Am. Chem. Soc. 125: 9274-9275.
Chyba, C.F., and G.D. McDonald. 1995. The origin of life in the solar system: current Issues. Ann. Rev. Earth Planet. Sci. 23: 215-249.
Chyba, C., and C. Sagan. 1991. Electrical energy sources for organic synthesis on the early Earth. Orig. Life Evol. Biosph. 21: 3-17.
Chyba, C., and C. Sagan. 1992. Endogenous production, exogenous delivery and impact-shock synthesis of organic molecules: an inventory for the origins of life. Nature 355: 125-132.
Chyba, C. F., P. J. Thomas, L. Brookshaw, and C. Sagan. 1990. Cometary delivery of organic molecules to the early Earth. Science 249: 366–373.
Ciftςioglu, N., and E.O. Kajander. 1998. Interaction of nanobacteria with cultured mammalian cells Pathophysiology 4: 259-270.
Costanzo, G., S. Pino, F. Ciciriello, and E. Di Mauro. 2009. Generation of long RNA chains in water. J. Biol. Chem. 284: 33206-16.
Cowen, R. 1995. History of life. Blackwell, Boston.
Crick, F.H.C. 1968. The origin of the genetic code. J. Molec. Biol. 38: 367-379.
Crick, F.H.C., and L.E. Orgel. 1973. Directed panspermia. Icarus 19: 341-345.
Davila, A.F. and C.P. McKay. 2014. Chance and necessity in biochemistry: Implications for the search for extraterrestrial biomarkers in Earth-like environments. Astrobiology 14: 534-540.
Davies, P. 2005. A quantum recipe for life. Nature 437: 819.
Davies, P.C.W. 1996. The transfer of viable microorganisms between planets. Ciba Foundation Symposium 202 (Evolution of hydrothermal ecosystems on Earth (and Mars?). Wiley, Chichester.
Deamer, D. 2017. The Role of Lipid Membranes in Life’s Origin. Life (Basel) 7: doi:https://doi.org/10.3390/life7010005.
Deamer, D. and B. Damer. 2017. Can life begin on Enceladus? A perspective from hydrothermal chemistry. Astrobiology 17: 834-839.
Deamer, D., J.P. Dworkin, S.A. Sandford, et al. 2002. The first cell membranes. Astrobiology 2: 371-381.
Deamer, D. W. and C. D. Georgiou. 2015. Hydrothermal conditions and the origin of cellular life. Astrobiology 15: 1091-1095.
Deamer, D.W., and R. Pashley. 1989. Amphiphilic components of the Murchison carbonaceous chondrite: surface properties and membrane formation Orig. Life Evol. Biosph. 19: 21-38.
Di Giulio, M. 2005. The ocean abysses witnessed the origin of the genetic code. Gene 346: 7-12.
Dyson, F. J. 1982. A model for the origin of life. J. Molec. Evol. 18: 344-350.
Dyson, F. J. 1999. Origins of Life. Cambridge University Press, Cambridge, U.K.
Feinberg, G., and R. Shapiro. 1980. Life beyond Earth: The Intelligent Earthling’s Guide to Life in the Universe. William Morrow and Company, Inc, New York.
Feller, G. 2017. Cryosphere and psychrophiles: insights into a cold origin of life? Life (Basel) 7: 25 (doi:https://doi.org/10.3390/life7020025).
Ferris, J.P. 1993. Prebiotic synthesis on minerals: RNA oligomer formation. In The Chemistry of Life’s Origins, edited by J. M. Greenberg, C. X. Mendoza-Gómez and V. Pirronello: Kluwer Acad. Publ.
Fox, S.W., and K. Dose. 1977. Molecular Evolution and the Origin of Life. Marcel Dekker, New York.
Franchi, M., E. Bramanti, L.M. Bonzi, et al. 1999. Clay-nucleic acid complexes: characteristics and implications for the preservation of genetic material in primeval habitats. Orig. Life Evol. Biosph. 29: 297-315.
Fraser, C. M., J. D. Gocayne, O. White, M. D. Adams, et al. 1995. The minimal gene complement of Mycoplasma genitalium. Science 270: 397-403.
Goldsmith, D., and T. Owen. 2003. The Search for Life in the Universe University Science Books, Sausalito.
Gull, M, M.A. Mojica, F.M. Fernandez, D.A. Gaul, and T.M. Orlando, et al. 2015. Nucleoside phosphorylation by the mineral schreibersite. Sci. Repts. 5: #17198; doi: 10.1038/srep17198.
Hadorn, M. and P. Eggenberger Hotz. 2010. DNA-mediated self-assembly of artificial vesicles. PLoS One 5: e9886.
Haldane, J.B.S. 1954. The origin of life Penguin Books, Harmondsworth.
Hartman, H. 1998. Photosynthesis and the origin of life Orig. Life Evol. Biosph. 28: 515-521.
Higgs, P. G. and R. E. Pudritz. 2009. A thermodynamic basis for prebiotic amino acid synthesis and the nature of the first genetic code. Astrobiology 9: 483-490.
Hoesl, M.G., Oehm, S., Durkin, P., Darmon, E., Peil, L., et al. 2015. Chemical evolution of a bacterial proteome. Ang. Chem.: doi:https://doi.org/10.1002/anie.201502868.
Horneck, G., D. Stöffler, S. Ott, U. Hornemann, C.S. Cockell, et al. 2008. Microbial rock inhabitants survive hypervelocity impacts on Mars-like host planets: first phase of lithopanspermia experimentally tested. Astrobiology 8: 17-44.
Horowitz, E. D., A. E. Engelhart, M. C. Chen, K. A. Quarles, et al. 2010. Intercalation as a means to suppress cyclization and promote polymerization of base-pairing oligonucleotides in a prebiotic world. Proc. Natl. Acad. Sci. USA 107: 5288-93.
Hose, L.D., A.N. Palmer, M.V. Palmer, et al. 2000. Microbiology and geochemistry in a hydrogen-sulphide-rich karst environment Chem. Geol. 169: 399-423.
Hoyle, F. 1983. The intelligent universe Michael Joseph, London.
Huber, C., and G. Wächtershäuser. 1998. Peptides by activation of amino acids with CO on (NiFe)S surfaces. Science 281: 670-672.
Huber, H., M.J. Hohn, R. Rachel, et al. 2002. A new phylum of Archaea represented by a nanosized hyperthermophilic symbiont. Nature 417: 63-67.
Hutchison, C. A., R. Y. Chuang, V. N. Noskov, N. Assad-Garcia, et al. 2016. Design and synthesis of a minimal bacterial genome. Science 351: 1414-U73; doi: https://doi.org/10.1126/science.aad6253
Irwin, L.N., and D. Schulze-Makuch. 2005. Prebiotic evolution of riboglycopeptides: bridging the entropy gap at the dawn of life on earth. International Conference on the Origin of Life, Beijing, P.R.C.
Kajander, E.O., I. Kuronen, K. Akerman, et al. 1997. Nanobacteria from blood, the smallest culturable autonomously replicating agent on Earth. Proc. SPIE 3111: 420-428.
Kajander, E.O., N. Ciftcioglu, M.A. Miller-Hjelle, et al. 2001. Nanobacteria: controversial pathogens in nephrolithiasis and polycystic kidney disease. Current Opinion in Nephrology and Hypertension 10: 445-452.
Kasting, J.F., and L.L. Brown. 1998. The early atmosphere as a source of biogenic compound. pp. 35-56 in B. A., ed. The Molecular Origins of Life. Cambridge University Press, Cambridge, UK.
Keller, M. A., D. Kampjut, S. A. Harrison, and M. Ralser. 2017. Sulfate radicals enable a non-enzymatic Krebs cycle precursor. Nat. Ecol. Evol. 1: 0083; doi https://doi.org/10.1038/s41559-017-0083.
Keosian, J. 1968. The Origin of Life. Reinhold, New York.
Khanna, M., and G. Stotzky. 1992. Transformation of Bacillus subtilis by DNA bound on montmorillonite and effect of DNase on the transforming ability of bound DNA. Applied Environmental Biology 58: 1930-1939.
Kompanichenko, V.N. 1996. Transition of precellular organic microsystems to a biotic state: environment and mechanism. Nanobiology 4: 39-45.
Lahav, N. 1991. Prebiotic co-evolution of self-replication and translation or RNA world? J Theor Biol 151: 531-539.
Lahav, N. 1994. Minerals and the origin of life: Hypotheses and experiments in heterogeneous chemistry. Heterogeneous Chem Rev 1: 159-179.
Lahav, N., and S. Nir. 1997. Emergence of template-and-sequence-directed (TSD) syntheses: I. A bio-geochemical model. Orig. Life Evol. Biosph. 27: 377-395.
Lathe, R. 2004. Fast tidal cycling and the origin of life. Icarus 168: 18-22.
Lazard, D., N. Lahav and J.B. Orenberg. 1987. The biogeochemical cycle of the adsorbed template. I: Formation of the template. Orig. Life Evol. Biosph. 17: 135-148.
Lazard, D., N. Lahav and J.B. Orenberg. 1988. The biogeochemical cycle of the adsorbed template. II: Selective adsorption of mononucleotides on adsorbed polynucleotide templates. Orig. Life Evol. Biosph. 18: 347-357.
Lazcano, A. 1994. The RNA world, its predecessors and descendants. pp. 70-80 in B. S, ed. Early life on Earth. Columbia University Press, New York.
Lazcano, A., and S.L. Miller. 1994. How long did it take for life to begin and evolve to cyanobacteria? J. Molec. Evol. 39: 549-554.
Lazcano, A. 2004. An answer in search of a question. Astrobiology 4: 469-471.
Lin, X., A. C. Yu, and T. F. Chan. 2017. Efforts and challenges in engineering the genetic code. Life (Basel) 7: doi:https://doi.org/10.3390/life7010012.
Lipps, J., and D. Schulze-Makuch. 2008. Origin of life in ice: prospects for the solar system and beyond. Astrobiology 8: 345.
Liu, R., and L.E. Orgel. 1997. Oxidative acylation using thioacids. Nature 389: 52-54.
Lorenz, M.G., and W. Wackernagel. 1987. Adsorption of DNA to sand and variable degradation rates of adsorbed DNA. Applied Environmental Microbiology 53: 2948-2952.
Luef, B., K. R. Frischkorn, K. C. Wrighton, H. Y. Holman, et al. 2015. Diverse uncultivated ultra-small bacterial cells in groundwater. Nature Commun. 6: 6372; doi: https://doi.org/10.1038/ncomms7372.
Madison, L.L. and G.W. Huisman, 1999. Metabolic engineering of poly (3-hydroxyalkanoates): from DNA to plastic. Microbiol. Mol. Biol. Rev. 63: 21-53.
Malyshev, D. A., K. Dhami, T. Lavergne, T. Chen, et al. 2014. A semi-synthetic organism with an expanded genetic alphabet. Nature 509: 385-388.
Manuel A.S. Santos, Mick F. Tuite, (1995) The CUG codon is decoded as serine and not leucine in. Nucleic Acids Research 23 (9):1481–1486
Margulis, L., and D. Sagan. 1995. What Is Life? Simon & Schuster, New York.
Martin D. Brasier, Richard Matthewman, Sean McMahon, David Wacey, (2011) Pumice as a Remarkable Substrate for the Origin of Life. Astrobiology 11 (7):725–735
Maurer, S. E., D. W. Deamer, J. M. Boncella, and P. A. Monnard. 2009. Chemical evolution of amphiphiles: glycerol monoacyl derivatives stabilize plausible prebiotic membranes. Astrobiology 9: 979-987.
Maurer, S. E. and G. Nguyen. 2016. Prebiotic vesicle formation and the necessity of salts. Orig. Life Evol. Biosph. 46: 215-22.
McClendon, J.H. 1999. The origin of life Earth Science Rev 47: 71-93.
McCollom, T.M. 1999. Methanogenesis as a potential source of chemical energy for primary biomass production by autotrophic organisms in hydrothermal systems on Europa. J. Geophys. Res.-Planets 104: 30729-30742.
Melosh, H.J. 2003. Exhange of meteorites (and life?) between stellar systems. Astrobiology 3: 207-215.
Miller, S.L. 1953. A production of amino acids under possible primitive earth conditions. Science 117: 528-529.
Miller, S.L., and L.E. Orgel. 1974. The Origins of Life on the Earth. Prentice-Hall.
Miller, S.L., and A. Lazcano. 1996. The origin and early evolution of life: prebiotic chemistry, the pre-RNA world, and time. Cell 85: 793-799.
Monnard, P.A., C.L. Apel, A. Kanavarioti, et al. 2002. Influence of ionic solutes on self-assembly and polymerization processes related to early forms of life: implications for a prebiotic aqueous medium. Astrobiology 2: 139-152.
Monnard, P.-A., C.L. Apel, A. Kanavarioti, and D.W. Deamer. 2004. Influence of ionic inorganic solutes on self-assembly and polymerization processes related to early forms of life: implications for a prebiotic aqueous medium. Astrobiology 2: 139-152.
Monnard, P.A., A. Kanavarioti and D.W. Deamer. 2003. Eutectic phase polymerization of activated ribonucleotide mixtures yields quasi-equimolar incorporation of purine and pyrimidine nucleobases. J Am Chem Soc 125: 13734-13740.
Muller, A.W.J. 1985. Thermosynthesis by biomembranes: energy gain from cyclic temperature changes. J. Ther. Biol. 115: 429-453.
Muller, A.W.J. 1993. A mechanism for thermosynthesis based on a thermotropic phase transition in an asymmetric biomembrane. Physiol. Chem. Phys. Med. NMR 25: 95-111.
Muller, A.W.J. 1995. Were the first organisms heat engines ? - a new model for biogenesis and the early evolution of biological energy conversion. Prog. Biophys. Molec. Biol. 63: 193-231.
Nielsen, P.E. 1993. Peptide nucleic acid (PNA): a model structure for the primordial genetic material Orig. Life Evol. Biosph. 23: 323-327.
Nisbet, E.G., and N.H. Sleep. 2001. The habitat and nature of early life. Nature 409: 1083-1091.
Oparin, A.I. 1938. Origin of Life. Dover reprinted 1953, New York.
Orenberg, J.B., S. Chan, J. Calderon, et al. 1985. Soluble minerals in chemical evolution. I. Adsorption of 5’-AMP on CaSO4--a model system. Orig. Life Evol. Biosph. 15: 121-129.
Orgel, L.E. 1998. The origin of life – a review of facts and speculations. Trends Biochem. Sci. 23: 491-495.
Oro, J., T. Mills and A. Lazcano. 1992. Comets and the formation of biochemical compounds on the primitive Earth--a review. Orig. Life Evol. Biosph. 21: 267-277.
Paget, E., L. Jocteur-Monrozoir and P. Simonet. 1992. Adsorption of DNA on clay minerals: protection against DNaseI and influence on gene transfer FEMS Microbiol. Lett. 97: 31-40.
Philip, G.K. and S.J. Freeland. 2011. Did evolution select a nonrandom “alphabet” of amino acids? Astrobiology 11: 235-240.
Prat, L., I. U. Heinemann, H. R. Aerni, J. Rinehart, P. O’Donoghue, D. Soll. 2012. Carbon source-dependent expansion of the genetic code in bacteria. Proc. Natl. Acad. Sci. USA 109: 21070-21075.
Price, P.B. 2010. Microbial life in Martian ice: a biotic origin of methane on Mars? Planet. Space Sci. 58: 1199-1206.
Pross, A. 2004. Causation and the origin of life. Metabolism or replication first? Orig. Life Evol. Biosph. 34: 307-321.
Qiao, Y., M. Li, R. Booth, and S. Mann. 2016. Predatory behaviour in synthetic protocell communities. Nature Chemistry: doi:https://doi.org/10.1038/nchem.2617.
Rios, A. C. and Y. Tor. 2012. Refining the genetic alphabet: a late-period selection pressure? Astrobiology 12: 884-91.
Ruf, A., B. Kanawati, N. Hertkorn, Q. Z. Yin, et al. 2017. Previously unknown class of metalorganic compounds revealed in meteorites. Proc. Natl. Acad. Sci. USA 114: 2819-2824.
Russell, M.J., and A.J. Hall. 1997. The emergence of life from monosulfide bubbles at a submarine hydrothermal redox and pH front. J. Geol. Soc. London 154: 377-402.
Russell, M.J., W. Nitschke, and E. Branscomb. 2013. The inevitable journey to being. Phil. Trans. R. Soc. B 368: 20120254.
Sagan, C., and E.E. Salpeter. 1976. Particles, environments, and possible ecologies in the jovian atmosphere. Astrophys. J. Suppl. Ser. 32: 624.
Saeidi, N., C. K. Wong, T. M. Lo, H. X. Nguyen, et al. 2011. Engineering microbes to sense and eradicate Pseudomonas aeruginosa, a human pathogen. Mol. Syst. Biol. 7: 521; doi https://doi.org/10.1038/msb.2011.55.
Scharf, C., Virgo, N., Cleaves, J., Aono, M., Aubert-Kato, N., et al. 2015. A strategy for origins of life research. Astrobiology 15: 1031-1042.
Schieber, J., and H.J. Arnott. 2003. Nannobacteria as a by-product of enzyme-driven tissue decay Geology 31: 717-720.
Schöning, K.-U., P. Scholz, W. Guntha, et al. 2000. Chemical etiology of nucleic acid structure: The alpha-threofuranosyl-(3’2’) oligonucleotide system. Science 290: 1347-1351.
Schreiber, U., O. Locker-Grütjen, and C. Mayer. 2012. Origin of life in deep-reaching tectonic faults. Orig. Life Evol. Biosph.: doi https://doi.org/10.1007/s11084-012-9267-4.
Schrödinger, E. 1944. What is Life? The Physical Aspect of the Living Cell. University Press, Cambridge.
Schulze-Makuch, D. 2002. At the crossroads between microbiology and planetology: a proposed iron cycle could sustain life in an ocean – and the ocean need not be on Earth. ASM News 68: 364-365.
Schulze-Makuch, D., Guan, H., Irwin, L.N., and Vega, E. 2002c. Redefining life: an ecological, thermodynamic, and bioinformatic approach. Fundamentals of Life. Elsevier SAS, Amsterdam, pp. 169-179.
Schulze-Makuch, D., and W. Bains. 2017. The Cosmic Zoo: Complex Life on Many Worlds. Chichester, U.K.: Springer Praxis.
Schwartz, A.W. 1993. Biology and theory: RNA and the origin of life. pp. 323-344 in J.M. Greenberg, C.X. Mendoza-Gomez and V. Pirronello, eds. The chemistry of life’s origins. Kluwer Acad. Publ.
Segre, D. and D. Lancet. 2000. Composing life. EMBO Rept. 1: 217-222.
Segre, D., D. Ben-Eli, and D. Lancet. 2000. Compositional genomes: prebiotic information transfer in mutually catalytic noncovalent assemblies. Proc. Natl. Acad. Sci. USA 97: 4112-7.
Sojo, V., B. Herschy, A. Whicher, E. Camprubi, N. Lane. 2016. The Origin of Life in Alkaline Hydrothermal Vents. Astrobiology 16: 181-197.
Srivatsan, S.G. 2004. Modeling prebiotic catalysis with nucleic acid-like polymers and its implications for the proposed RNA world. Pure Appl. Chem. 76: 2085-2099.
Stetter, K.O. 1998. Hyperthermophiles and their possible role as ancestors of modern life pp. 315-335 in B. A., ed. The Molecular Origins of Life. Cambridge University Press.
Stevens, T.O., and J.P. McKinley. 1995. Lithoautotrophic microbial ecosystems in deep basalt aquifers. Science 270: 450-454.
Stribling, R., and S.L. Miller. 1991. Template-directed synthesis of oligonucleotides under eutectic conditions. J. Mol. Evol. 32: 289-295.
Tajika, E., and T. Matsui. 1993. Degassing History and Carbon-Cycle of the Earth - from an Impact-Induced Steam Atmosphere to the Present Atmosphere. Lithos 30: 267-280.
Taylor, D.J., M.J. Ballinger, S.M. Bowman, and J.A. Bruenn. 2013. Virus-host coevolution under a modified nuclear genetic code. PeerJ 1: e50; doi: https://doi.org/10.7717/peerj.50.
Trinks, H., W. Schroder and C.K. Biebricher. 2005. Ice and the origin of life. Orig. Life Evol. Biosph. 35: 429-445.
Turian, G. 2003. Biogenic bipolarity - A new approach to the origin of life. Arch. Sci. 56: 155-182.
Vlassov, A.V., B.H. Johnston, L.F. Landweber, et al. 2004. Ligation activity of fragmented ribozymes in frozen solution: implications for the RNA world. Nucleic Acids Res 32: 2966-2974.
Wächtershäuser, G. 1988. Before enzymes and templates: theory of surface metabolism. Microbiol Rev 52: 452-484.
Wächtershäuser, G. 1994. Vitalists and virulists: a theory of self-expanding reproduction. pp. 124-132 in S. Bengtson, ed. Early life on Earth. Columbia University Press, New York.
Wächtershäuser, G. 2007. On the chemistry and evolution of the pioneer organism. Chem Biodivers 4: 584-602.
Walker, J.C.G. 1977. Evolution of the atmosphere Macmillan, New York.
Wang, Q., A.R. Parrish, L.Wang. 2009. Expanding the genetic code for biological studies. Chemistry & Biology 16: 323–336.
Weiss, M. C., F. L. Sousa, N. Mrnjavac, S. Neukirchen, et al. 2016. The physiology and habitat of the last universal common ancestor. Nat. Microbiol. 1: 16116.
Westall, F., M.J. de Wit, J. Dann, et al. 2001. Early Archean fossil bacteria and biofilms in hydrothermally-influenced sediments from the Barberton greenstone belt, South Africa. Precambrian Research 106: 93-116.
Woese, C. 1979. A proposal concerning the origin of life on the planet Earth. J Molec Evol 13: 95-101.
Xie, J. and P. G. Schultz. 2005. Adding amino acids to the genetic repertoire. Curr. Opin. Chem. Biol. 9: 548-554.
Yamao, F., A. Muto, Y. Kawauchi, M. Iwami, S. Iwagami, et al. 1985. UGA is read as tryptophan in Mycoplasma capricolum. Proc. Natl. Acad. Sci USA 82: 2306-2309.
Yang, Z., F. Chen, J.B. Alvarado, and S.A. Benner. 2011. Amplification, mutation, and sequencing of a six-letter synthetic genetic system. J. Am. Chem. Soc. 133: 15105–15112.
Zhang, Y., P.V. Baranov, J.F. Atkins, and V.N. Gladyshev. 2005. Pyrrolysine and selenocysteine use dissimilar coding strategies. J. Biol. Chem. 280: 20740-20751.
Zamudio, G.S. and M.V. José. 2017. On the uniqueness of the standard genetic code. Life 7: doi: https://doi.org/10.3390/life7010007.
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Schulze-Makuch, D., Irwin, L.N. (2018). Origin of Life. In: Life in the Universe. Springer Praxis Books(). Springer, Cham. https://doi.org/10.1007/978-3-319-97658-7_3
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