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Category III: Atypical

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Abstract

A subgroup of specimens exists within pulmonary cytopathology which demonstrate cytomorphologic features beyond that seen in typical benign and reactive conditions but lack the degree of cellular changes warranting a diagnosis of suspicious for malignancy; such cases are best categorized as “atypical.” Although these cases are associated with a considerable risk of malignancy in follow-up studies, a significant percentage are a result of profound inflammatory conditions, acute and chronic lung injury, and treatment effects. The cytomorphologic criteria for designation of specimens as “atypical” are described and illustrated.

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Authors and Affiliations

  1. Department of Pathology and Laboratory Medicine, Cytopathology Section, Hospital of the University of Pennsylvania Health System, Philadelphia, PA, USA

    Gordon H. Yu

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  1. Gordon H. Yu
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Correspondence to Gordon H. Yu .

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Editors and Affiliations

  1. Department of Pathology and Anatomical Sciences, University of Missouri, Columbia, MO, USA

    Lester J. Layfield

  2. Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA

    Zubair Baloch

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Yu, G.H. (2019). Category III: Atypical. In: Layfield, L., Baloch, Z. (eds) The Papanicolaou Society of Cytopathology System for Reporting Respiratory Cytology. Springer, Cham. https://doi.org/10.1007/978-3-319-97235-0_4

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  • DOI: https://doi.org/10.1007/978-3-319-97235-0_4

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-97234-3

  • Online ISBN: 978-3-319-97235-0

  • eBook Packages: MedicineMedicine (R0)

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