Abstract
Chronic deciduitis is characterized by the presence of lymphoplasmacytic inflammation or, in the absence of plasma cells, diffuse and intense (>50/HPF) non-perivascular lymphocytes in the decidua. Chronic deciduitis is one of a group of chronic placental inflammatory lesions, which include VUE and chronic chorioamnionitis. While the exact cause is not known, it is suggested that immune mechanisms related to maternal anti-fetal rejection, or alternatively, chronic microbial infection, may be involved in causation. Chronic deciduitis is an association with preterm labour. Chronic deciduitis is more frequent in chromosomally normal and abnormal spontaneous miscarriage, when compared to elective terminations, suggesting a role in first trimester pregnancy loss.
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References
Khong TY, Bendon RW, Qureshi F, Redline RW, Gould S, Stallmach T, et al. Chronic deciduitis in the placental basal plate: definition and interobserver reliability. Hum Pathol. 2000;31:292–5.
Kim CJ, Romero R, Kusanovic JP, Yoo W, Dong Z, Topping V, et al. The frequency, clinical significance, and pathological features of chronic chorioamnionitis: a lesion associated with spontaneous preterm birth. Mod Pathol. 2010;23:1000–11.
Kim CJ, Romero R, Chaemsaithong P, Kim J-S. Chronic inflammation of the placenta: definition, classification, pathogenesis, and clinical significance. Am J Obstet Gynecol. 2015;213:S53–69.
Lee JH, Romero R, Xu Y, Kim J-S, Park JY, Kusanovic JP, et al. Maternal HLA panel-reactive antibodies in early gestation positively correlate with chronic chorioamnionitis: evidence in support of the chronic nature of maternal anti-fetal rejection. Am J Reprod Immunol. 2011;66:510–26.
Lee JY, Hong J-S, Kim EN, Ahn S, Choe J, Hwang D, et al. Placental C4d is a common feature of chromosomally normal and abnormal miscarriages. Virchows Arch. 2014;464:613–20.
Perni SC, Predanik M, Cho JE, Baergen RN. Placental pathology and pregnancy outcomes in donor and non-donor oocyte in vitro fertilization pregnancies. J Perinat Med. 2005;33:27–32.
Gundogan F, Bianchi DW, Scherjon SA, Roberts DJ. Placental pathology in egg donor pregnancies. Fertil Steril. 2010;93:397–404.
Edmondson N, Bocking A, Machin G, Rizek R, Watson C, Keating S. The prevalence of chronic deciduitis in cases of preterm labor without clinical chorioamnionitis. Pediatr Dev Pathol. 2009;12:16–21.
Kraus FT, Redline RW, Gersell DJ, Nelson DM, Dicke DK. Inflammation and infection. Placental pathology: atlas of non-tumor pathology (first series, fascicle 3). Washington (DC): American Registry of Pathology; 2004. p. 75–115.
Redline RW. Villitis of unknown etiology: noninfectious chronic villitis in the placenta. Hum Pathol. 2007;38:1439–46.
Redline R, Zaragoza M, Hassold T. Prevalence of developmental and inflammatory lesions in nonmolar first-trimester abortions. Hum Pathol. 1999;30:93–100.
Ernst LM, Linn RL, Mintern L, Miller ES. Pathologic associations with morbidly adherent placenta: potential insights into pathogenesis. Pediatr Devel Pathol. 2017;20:387–96.
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Jacques, S.M., Qureshi, F., Ernst, L.M. (2019). Chronic Deciduitis. In: Khong, T., Mooney, E., Nikkels, P., Morgan, T., Gordijn, S. (eds) Pathology of the Placenta. Springer, Cham. https://doi.org/10.1007/978-3-319-97214-5_33
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DOI: https://doi.org/10.1007/978-3-319-97214-5_33
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