Abstract
Unlike other microscopic lesions, villous oedema is often a descriptive, not a diagnostic, term. It is characterised by an accumulation of fluid in the villous stroma and between capillaries and the trophoblast layer. Diffuse villous stromal oedema may indicate fetal hydrops (immune/non-immune), but histologic assessment is often unable to establish an underlying diagnosis. Patchy or focal villous oedema may be insignificant or may be seen in association with established regional flow changes in the fetal circulation.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Naeye RL, Maisels MJ, Lorenz RP, Botti JJ. The clinical significance of placental villous edema. Pediatrics. 1983;71:588–94.
Shen-Schwarz S, Ruchelli E, Brown D. Villous oedema of the placenta: a clinicopathological study. Placenta. 1989;10:297–307.
Treacy A, Higgins M, Kearney JM, McAuliffe F, Mooney EE. Delayed villous maturation of the placenta: quantitative assessment in different cohorts. Pediatr Dev Pathol. 2013;16:63–6.
Bukowski R, Hansen NI, Pinar H, Willinger M, Reddy UM, Parker CB, et al. Altered fetal growth, placental abnormalities, and stillbirth. PLoS One. 2017;12:e0182874.
Redline RW. Disorders of the placental circulation and the fetal brain. Clin Perinatol. 2009;36:549–59.
Straughen JK, Misra DP, Divine G, Shah R, Perez G, VanHorn S, Onbreyt V, Dygulska B, Schmitt R, Lederman S, Narula P, Salafia CM. The association between placental histopathology and autism spectrum disorder. Placenta. 2017;57:183–8.
Redline RW, Wilson-Costello D, Borawski E, Fanaroff AA, Hack M. Placental lesions associated with neurologic impairment and cerebral palsy in very low-birth-weight infants. Arch Pathol Lab Med. 1998;122:1091–8.
Fox H, Sebire NJ. Pathology of the placenta. 3rd ed. London: Saunders Elsevier; 2007.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2019 Springer Nature Switzerland AG
About this chapter
Cite this chapter
Kelehan, P., Downey, P. (2019). Villous Oedema. In: Khong, T., Mooney, E., Nikkels, P., Morgan, T., Gordijn, S. (eds) Pathology of the Placenta. Springer, Cham. https://doi.org/10.1007/978-3-319-97214-5_21
Download citation
DOI: https://doi.org/10.1007/978-3-319-97214-5_21
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-97213-8
Online ISBN: 978-3-319-97214-5
eBook Packages: MedicineMedicine (R0)