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Preoperative Systemic Therapy for Non-Inflammatory Locally Advanced Breast Cancer

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Breast Cancer

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Abstract

Preoperative systemic therapy is a commonly used therapeutic approach to treat locally advanced and operable, primarily non-operable, or inflammatory breast cancer. Preoperative systemic therapy should be an option for patients who would require adjuvant systemic therapy. Neoadjuvant therapy is most appropriate for patients likely to have a good locoregional response, regardless of tumor size at presentation, including those with HER2-positive or triple-negative breast cancers. The decision regarding neoadjuvant treatment should be made after a discussion of the patient’s clinical, histological, and imaging characteristics by a multidisciplinary oncology board that includes surgical oncologists, medical oncologists, radiation oncologists, radiologists, and pathologists.

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Author information

Authors and Affiliations

  1. Internal Medicine, Department of Medical Oncology, Memorial Hospital, Istanbul, Turkey

    Serkan Keskin

  2. Internal Medicine, Medical Oncology, Istanbul Medical Faculty, Department of Medical Oncology, Institute of Oncology, Istanbul University, Istanbul, Turkey

    Adnan Aydiner

Authors
  1. Serkan Keskin
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  2. Adnan Aydiner
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Editor information

Editors and Affiliations

  1. Internal Medicine, Medical Oncology, Istanbul Medical Faculty, Department of Medical Oncology, Institute of Oncology, Istanbul University, Istanbul, Turkey

    Adnan Aydiner

  2. General Surgery, Istanbul Medical Faculty, Department of Surgery, Istanbul University, Istanbul, Turkey

    Abdullah Igci

  3. Surgical Oncology, Magee-Women’s Hospital, University of Pittsburgh Medical Centre, Pittsburgh, PA, USA

    Atilla Soran

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Keskin, S., Aydiner, A. (2019). Preoperative Systemic Therapy for Non-Inflammatory Locally Advanced Breast Cancer. In: Aydiner, A., Igci, A., Soran, A. (eds) Breast Cancer . Springer, Cham. https://doi.org/10.1007/978-3-319-96947-3_10

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  • DOI: https://doi.org/10.1007/978-3-319-96947-3_10

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-96946-6

  • Online ISBN: 978-3-319-96947-3

  • eBook Packages: MedicineMedicine (R0)

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