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Grass Pea: Remodeling an Ancient Insurance Crop for Climate Resilience

Chapter

Abstract

Grass pea (Lathyrus sativus) is a hardy legume grown for food, feed, and fodder. It is an ancient crop which has been cultivated for more than 8000 years because of its tolerance of drought, flooding, salinity, and poor soils, its ability to fix nitrogen, and its seeds with high levels of protein. These traits make it an outstanding crop for ensuring nutritional security (particularly for protein) for resource-poor farmers, especially in the face of impending changes in climate. However, the presence of β-N-oxalyl-L-α,β-diaminopropionic acid (β-ODAP or ODAP), a neurotoxin present in the seeds and vegetative tissues of grass pea, has limited its breeding and modern-day cultivation. β-ODAP causes lathyrism, a paralysis of the lower limbs that occurs in epidemics in undernourished communities. This has resulted in grass pea being an “orphan crop” whose potential has not been fully realized due to lack of markets and research funding. The recent emphasis on climate smart crops has refocused attention on this very promising crop. Genomic resources and low-ODAP lines are being developed, and it is hoped that these will soon allow grass pea to reach its full potential as a resilient protein crop for food and nutritional security through sustainable agriculture in the face of climate change.

Keywords

Lathyrus Protein Climate smart Food security Nutrition Genetic maps β-ODAP 

References

  1. Abberton M, Conant R, Batello C (eds) (2010) Grassland carbon sequestration: management, policy and economics. Integrated Crop Management. In: Proceedings of the workshop on the role of grassland carbon sequestration in the mitigation of climate change, FAO, Rome, Apr 2009Google Scholar
  2. Addis G, Narayan RKJ (2000) Interspecific hybridisation of Lathyrus sativus (guaya) with wild Lathyrus species and embryo rescue. Afr Crop Sci J 8:129–136CrossRefGoogle Scholar
  3. Ahlawat IPS, Singh A, Saraf CS (1981) Effects of winter legumes on the nitrogen economy and productivity of succeeding cereals. Exp Agri 17:57–62CrossRefGoogle Scholar
  4. Allkin R, Goyder DJ, Bisby FA, White RJ (1986) Names and synonyms of species and subspecies in the Vicieae. Vicieae Database Proj 7:1–75Google Scholar
  5. Almeida NF, Leitao ST, Krezdorn N, Rotter B, Winter P, Rubiales D et al (2014a) Allelic diversity in the transcriptomes of contrasting rust-infected genotypes of Lathyrus sativus, a lasting resource for smart breeding. BMC Plant Biol 14:376.  https://doi.org/10.1186/s12870-014-0376-2CrossRefPubMedPubMedCentralGoogle Scholar
  6. Almeida NF, Leitão ST, Caminero C, Torres AM, Rubiales D, Patto MCV (2014b) Transferability of molecular markers from major legumes to Lathyrus spp. for their application in mapping and diversity studies. Mol Biol Rep 41:269–283CrossRefGoogle Scholar
  7. Almeida NF, Rubiales D, Patto MCV (2015) Grass pea. In: De Ron AM (ed) Grain legumes, handbook of plant breeding. Springer, Heidelberg, Germany, pp 251–265Google Scholar
  8. Anand U (2016) ICMR panel clears ‘unsafe’ khesari dal banned in 1961. The Indian Express. http://indianexpress.com/article/india/india-news-india/icmr-panel-clears-unsafe-khesari-dal-banned-in-61/
  9. Bailey-Serres J, Voesenek LACJ (2008) Flooding stress: acclimations and genetic diversity. Annu Rev Plant Biol 59:313–339CrossRefGoogle Scholar
  10. Bangladesh Bureau of Statistics (2016) Yearbook of Agricultural Statistics-2015 Dhaka, Bangladesh p 27Google Scholar
  11. Barik DP, Mohapatra U, Chand PK (2005) Transgenic grasspea (Lathyrus sativus L.): factors influencing Agrobacterium-mediated transformation and regeneration. Plant Cell Rep 24:523.  https://doi.org/10.1007/s00299-005-0957-5
  12. Barik D, Acharya L, Mukherjee A, Chand P (2007) Analysis of genetic diversity among selected grass pea (Lathyrus sativus L.) genotypes using RAPD markers. Z Naturforsch 62:869–874CrossRefGoogle Scholar
  13. Barna K, Mehta SL (1995) Genetic transformation and somatic embryogenesis in Lathyrus sativus. J Plant Biochem Biotechnol 4:67.  https://doi.org/10.1007/BF03262955CrossRefGoogle Scholar
  14. Barpete S, Parmar D, Sharma NC, Kumar S (2012). Karyotype analysis in grass pea (Lathyrus sativus L.). J Food Legum 25:14–17Google Scholar
  15. Battistin A, Fernandez A (1994) Karyotypes of four species of South America natives and one cultivated species of Lathyrus L. Caryologia 47:325–330CrossRefGoogle Scholar
  16. Bennett MD, Leitch IJ (2012) Angiosperm DNA C-values database, release 6.0, Dec 2012 edn. London, UKGoogle Scholar
  17. Bhattacharyya M, Martin C, Smith A (1993) The importance of starch biosynthesis in the wrinkled seed shape character of peas studied by Mendel. Plant Mol Biol 22:525–531CrossRefGoogle Scholar
  18. Biazzi E, Nazzicari N, Pecetti L, Brummer EC, Palmonari A et al (2017) Genome-wide association mapping and genomic selection for alfalfa (Medicago sativa) forage quality traits. PLoS ONE 12(1):e0169234.  https://doi.org/10.1371/journal.pone.0169234CrossRefPubMedPubMedCentralGoogle Scholar
  19. Bogracheva TY, Cairns P, Noel TR, Hulleman S, Wang TL et al (1999) The effect of mutant genes at the r, rb, rug3, rug4, rug5 and lam loci on the granular structure and physico–chemical properties of pea seed starch. Carbohyd Polym 39:303–314CrossRefGoogle Scholar
  20. Bohra A, Jha UC, Kavi Kishor PB, Pandey S, Singh NP (2014) Genomics and molecular breeding in lesser explored pulse crops: current trends and future opportunities. Biotechnol Adv 32:1410–1428CrossRefGoogle Scholar
  21. Butler A, Tesfay Z, D’Andrea C, Lyons D (1999) The ethnobotany of Lathyrus sativus L. in the highlands of Ethiopia. In: Van der Veen M (ed) The exploitation of plant resources in ancient Africa. Springer, Heidelberg, Germany, pp 123–136CrossRefGoogle Scholar
  22. Byerlee D, De Janvry A, Sadoulet E, Townsend R, Klytchnikova I (2007). World Development Report 2008: agriculture for development. World Bank, Washington, DC, USAGoogle Scholar
  23. Cai W, Borlace S, Lengaigne M, van Rensch P, Collins M et al (2014) Increasing frequency of extreme El Niño events due to greenhouse warming. Nat Clim Chang 4:111.  https://doi.org/10.1038/nclimate2100CrossRefGoogle Scholar
  24. Campbell CG (1997) Grass pea. Lathyrus sativus L. Promoting the conservation and use of underutilized and neglected crops, vol 18. Institute of Plant Genetics and Crop Plant Research, Gatersleben/International Plant Genetic Resources Institute, Rome, ItalyGoogle Scholar
  25. Campbell CG et al (1994) Current status and future strategy in breeding grasspea (Lathyrus sativus). In: Muehlbauer FJ, Kaiser WJ (eds) Expanding the production and use of cool season food legumes. Current plant science and biotechnology in agriculture, vol 19. Springer, Dordrecht.  https://doi.org/10.1007/978-94-011-0798-3_3
  26. Carriedo LG, Maloof JN, Brady SM (2016) Molecular control of crop shade avoidance. Curr Opin Plant Biol 30:151–158.  https://doi.org/10.1016/j.pbi.2016.03.005CrossRefPubMedGoogle Scholar
  27. Casey R, Davies DR (eds) (1993) Peas: genetics, molecular biology and biotechnology. CABI, Wallingford, Oxford, UKGoogle Scholar
  28. Chakraborty S, Mitra J, Samanta MK, Sikdar N, Bhattacharyya J et al (2018) Tissue specific expression and in-silico characterization of a putative cysteine synthase gene from Lathyrus sativus L. Gene Express Patt 27:128–134.  https://doi.org/10.1016/j.gep.2017.12.001CrossRefGoogle Scholar
  29. Chandra A (2011) Use of EST database markers from Medicago truncatula in the transferability to other forage legumes. J Environ Biol 32:347–354PubMedGoogle Scholar
  30. Chapman MA (2015) Transcriptome sequencing and marker development for four underutilized legumes. Appl Plant Sci 3(2):1400111.  https://doi.org/10.3732/apps.1400111
  31. Chowdhury MA, Slinkard AE (1997) Natural outcrossing in grass pea. J Hered 88:154–156CrossRefGoogle Scholar
  32. Chowdhury MA, Slinkard AE (1999) Linkage of random amplified polymorphic DNA, isozyme and morphological markers in grasspea (Lathyrus sativus). J Agri Sci 33:389–395CrossRefGoogle Scholar
  33. Chtourou-Ghorbel N, Lauga B, Combes D, Marrakchi M (2001) Comparative genetic diversity studies in the genus Lathyrus using RFLP and RAPD markers. Lathyrus Lathyrism Newsl 2:62–68Google Scholar
  34. Clancey B (2009) World pulse outlook. Stat Publishing, Vancouver, CanadaGoogle Scholar
  35. Clemente A, Arques MC, Dalmais M, Le Signor C, Chinoy C et al (2015) Eliminating anti-nutritional plant food proteins: the case of seed protease inhibitors in pea. PLoS ONE 10:e0134634.  https://doi.org/10.1371/journal.pone.0134634CrossRefPubMedPubMedCentralGoogle Scholar
  36. Cohn DF, Streifler M (1983) Intoxication by the Chickling Pea (Lathyrus sativus): nervous system and skeletal findings. In: Chambers CM, Chambers PL, Gitter S (eds) Toxicology in the use, misuse, and abuse of food, drugs, and chemicals. Archives of toxicology (Supplement), vol 6. Springer, Berlin, Heidelberg, Germany, pp 190–193Google Scholar
  37. Colbert T, Till BJ, Tompa R, Reynolds S, Steine MN et al (2001) High-throughput screening for induced point mutations. Plant Physiol 126:480–484CrossRefGoogle Scholar
  38. Comai L, Young K, Till BJ, Reynolds SH, Greene EA et al (2004) Efficient discovery of DNA polymorphisms in natural populations by Ecotilling. Plant J 37:778–786CrossRefGoogle Scholar
  39. Dai A (2013) Increasing drought under global warming in observations and models. Nat Clim Change 3:52–58CrossRefGoogle Scholar
  40. Dastur DK, Iyer CGS (1959) Lathyrism versus odoratism. Nutr Rev 17:33–36.  https://doi.org/10.1111/j.1753-48871959.tb06376.xCrossRefPubMedGoogle Scholar
  41. David S, Sperling L (1999) Improving technology delivery mechanisms: lessons from bean seed systems research in eastern and central Africa. Agri Hum Values 16:381–388.  https://doi.org/10.1023/a:1007603902380CrossRefGoogle Scholar
  42. Deshpande SS, Campbell CG (1992) Genotype variation in BOAA, condensed tannins, phenolics and enzyme inhibitors of grass pea (Lathyrus sativus). Can J Plant Sci 72(4):1037–1047CrossRefGoogle Scholar
  43. Ding T, Yang Z, Wei X, Yuan F, Yin S et al (2018a) Evaluation of salt-tolerant germplasm and screening of the salt-tolerance traits of sweet sorghum in the germination stage. Funct Plant Biol 45:1073–1081.  https://doi.org/10.1071/FP18009CrossRefGoogle Scholar
  44. Ding S, Wang M, Fang S, Xu H, Fan H et al (2018b) D-dencichine regulates thrombopoiesis by promoting megakaryocyte adhesion, migration and proplatelet formation. Front Pharmacol 9:297.  https://doi.org/10.3389/fphar.2018.00297CrossRefPubMedPubMedCentralGoogle Scholar
  45. Dixit GP, Parihar AK, Bohra A, Singh NP (2016) Achievements and prospects of grass pea (Lathyrus sativus L.) improvement for sustainable food production. Crop J 4:407–416.  https://doi.org/10.1016/j.cj.2016.06.008CrossRefGoogle Scholar
  46. Dubos C, Stracke R, Grotewold E, Weisshaar B, Martin C et al (2010) MYB transcription factors in Arabidopsis. Trends Plant Sci 15:573–581.  https://doi.org/10.1016/j.tplants.2010.06.005CrossRefPubMedGoogle Scholar
  47. Emmrich PMF (2017) Genetic improvement of grass pea (Lathyrus sativus) for low β-L-ODAP Content. PhD Thesis, University of East Anglia, Norwich. https://ueaeprints.uea.ac.uk/63944/
  48. Eslavath RK, Sharma D, Bin Omar NAM, Chikati R, Teli MK et al (2016) β-N-oxalyl-l-α, β-diaminopropionic acid induces HRE expression by inhibiting HIF-prolyl hydroxylase-2 in normoxic conditions. Eur J Pharmacol 791:405–411.  https://doi.org/10.1016/j.ejphar.2016.07.007CrossRefPubMedGoogle Scholar
  49. European Court of Justice Ruling, ECLI:EU:C:2018:583 (2018) http://curia.europa.eu/juris/documents.jsf?num=C-528/16
  50. Fikre A, Korbu L, Kuo YH, Lambein F (2008) The contents of the neuro-excitatory amino acid β-ODAP (β-N-oxalyl-l-α, β-diaminopropionic acid), and other free and protein amino acids in the seeds of different genotypes of grass pea (Lathyrus sativus L.). Food Chem 110:422–427CrossRefGoogle Scholar
  51. Fikre A, Negwo T, Kuo YH, Lambein F, Ahmed S (2011) Climatic, edaphic and altitudinal factors affecting yield and toxicity of Lathyrus sativus grown at five locations in Ethiopia. Food Chem Toxicol 49:623–630.  https://doi.org/10.1016/j.fct.2010.06.055CrossRefPubMedGoogle Scholar
  52. Fulton TM, Van der Hoeven R, Eannetta NT, Tanksley SD (2002) Identification, analysis, and utilization of conserved ortholog set markers for comparative genomics in higher plants. Plant Cell 14(7):1457–1467.  https://doi.org/10.1105/tpc.010479CrossRefPubMedPubMedCentralGoogle Scholar
  53. Gaj T, Gersbach CA, Barbas CF (2013) ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering. Trends Biotechnol 31(7):397–405CrossRefGoogle Scholar
  54. García-Hernández JL, Orona-Castillo I, Preciado-Rangel P, Flores-Hernández A, Murillo-Amador B, Troyo-Diéguez E (2010) Nutrients use efficiency in legume crops to climatic changes. In: Yadav S, Redden R (eds) Climate change and management of cool season grain legume crops. Springer, Dordrecht, Netherlands, pp 193–206CrossRefGoogle Scholar
  55. Ge L, Yu J, Wang H, Luth D, Bai G et al (2016) Increasing seed size and quality by manipulating BIG SEEDS1 in legume species. Proc Natl Acad Sci USA 113:12414–12419.  https://doi.org/10.1073/pnas.1611763113CrossRefPubMedGoogle Scholar
  56. Getahun H, Lambein F, Vanhoorne M, Van der Stuyft P (2003) Food-aid cereals to reduce neurolathyrism related to grass-pea preparations during famine. Lancet 362:1808–1810CrossRefGoogle Scholar
  57. Gharti DB, Darai R, Subedi S, Sarker A, Kumar S (2014) Grain legumes in Nepal: present scenario and future prospects. World J Agri Res 2:216–222.  https://doi.org/10.12691/wjar-2-5-3CrossRefGoogle Scholar
  58. Girma D, Korbu L (2012) Genetic improvement of grass pea (Lathyrus sativus) in Ethiopia: an unfulfilled promise. Plant Breed 131:231–236CrossRefGoogle Scholar
  59. Girma A, Tefera B, Dadi L (2011) Grass pea and neurolathyrism: farmers’ perception on its consumption and protective measure in North Shewa, Ethiopia. Food Chem Toxicol 49:668–672.  https://doi.org/10.1016/j.fct.2010.08.040CrossRefPubMedGoogle Scholar
  60. Glowacka K, Kromdijk J, Kucera K, Xie J, Cavanagh AP et al (2018) Photosystem II Subunit S overexpression increases the efficiency of water use in a field-grown crop. Nat Commun 9:868.  https://doi.org/10.1038/s41467-018-03231-xCrossRefPubMedPubMedCentralGoogle Scholar
  61. Goldenberg JB (1965) afila, a new mutation in pea (Pisum sativum L.). Biol Genet 1:27–31Google Scholar
  62. Gou J, Debnath S, Sun L, Flanagan A, Tang Y et al (2018) From model to crop: functional characterization of SPL8 in M. truncatula led to genetic improvement of biomass yield and abiotic stress tolerance in alfalfa. Plant Biotechnol J 16:951–962CrossRefGoogle Scholar
  63. Gourlay CW, Hofer JMI, Ellis THN (2000) Pea compound leaf architecture Is regulated by interactions among the genes UNIFOLIATA, COCHLEATA, AFILA, and TENDRIL-LESS. Plant Cell 12:1279–1294.  https://doi.org/10.1105/tpc.12.8.1279CrossRefPubMedPubMedCentralGoogle Scholar
  64. Gurung AM, Pang CK (2013) Lathyrus. In: Kole C (ed) Wild Crop Relatives: Genomic and Breeding Resources: Legume Crops and Forages. Springer Verlag, Heidelberg, Germany, pp 117–126Google Scholar
  65. Gutierrez JF, Vaquero F, Vences FJ (2001) Genetic mapping of isozyme loci in Lathyrus sativus L. Lathyrus Lathyrism Newsl 2:74–78Google Scholar
  66. Gutierrez MV, Patto MCV, Huguet T, Cubero JI, Moreno MT et al (2005) Cross-species amplification of Medicago truncatula microsatellites across three major pulse crops. Theor Appl Genet 110:1210–1217CrossRefGoogle Scholar
  67. Haimanot RT, Feleke A, Lambein F (2005) Is lathyrism still endemic in northern Ethiopia?—The case of Legambo Woreda (district) in the South Wollo Zone, Amhara National Regional State. Ethiop J Heal Dev 19:230–236Google Scholar
  68. Hao X, Yang T, Liu R, Hu J, Yao Y et al (2017) An RNA sequencing transcriptome analysis of grass pea (Lathyrus sativus L.) and development of SSR and KASP markers. Front Plant Sci 8:1873.  https://doi.org/10.3389/fpls.2017.01873
  69. Harlan JR, de Wet JMJ (1971) Towards a rational classification of cultivated plants. Taxon 20:509–517CrossRefGoogle Scholar
  70. Heywood V, Casas A, Ford-Lloyd B, Kell S, Maxted N (2007) Conservation and sustainable use of crop wild relatives. Agri Ecosyst Environ 121:245–255CrossRefGoogle Scholar
  71. Hillocks RJ, Maruthi MN (2012) Grass pea (Lathyrus sativus): Is there a case for further crop improvement? Euphytica 186:647–654CrossRefGoogle Scholar
  72. Humphry M, Reinstädler A, Ivanov S, Bisseling T, Panstruga R (2011) Durable broad-spectrum powdery mildew resistance in pea er1 plants is conferred by natural loss-of-function mutations in PsMLO1. Mol Plant Pathol 12:866–867.  https://doi.org/10.1111/j.1364-3703.2011.00718.xCrossRefPubMedGoogle Scholar
  73. Joshi M (1998) Status of grass pea (Lathyrus sativus L.) genetic resources in Nepal. In: Mathur PN, Rao VR, Arora RK (eds) Lathyrus genetic resources network: proceedings of a IPGRI-ICARDA-ICAR Regional Working Group Meeting, National Bureau of Plant Genetic Resources, New Delhi, India, pp 22–29, 8–10 Dec 1997Google Scholar
  74. Karaba A, Dixit S, Greco R, Aharoni A, Trijatmiko KR (2007) Improvement of water use efficiency in rice by expression of HARDY, an Arabidopsis drought and salt tolerance gene. Proc Natl Acad Sci USA 104(39):15270–15275.  https://doi.org/10.1073/pnas.0707294104CrossRefPubMedGoogle Scholar
  75. Kim YH, Kim MD, Park SC, Yang KS, Jeong JC et al (2011) SCOF-1-expressing transgenic sweet potato plants show enhanced tolerance to low-temperature stress. Plant Physiol Biochem 49:1436–1441.  https://doi.org/10.1016/j.plaphy.2011.09.002CrossRefPubMedGoogle Scholar
  76. Kole C (2017) Combating climate change for FNEE security. In: International conference on the status of plant & animal genome research, San Diego, CA, 14–18 Jan 2017Google Scholar
  77. Kumar S, Bejiga G, Ahmed S, Nakkoul H, Sarker A (2011) Genetic improvement of grass pea for low neurotoxin (ODAP) content. Food Chem Toxicol 49:589–600CrossRefGoogle Scholar
  78. Kumar V, Chattopadhyay A, Ghosh S, Irfan M, Chakraborty N et al (2016) Improving nutritional quality and fungal tolerance in soya bean and grass pea by expressing an oxalate decarboxylase. Plant Biotechnol J 14:1394–1405.  https://doi.org/10.1111/pbi.12503CrossRefPubMedGoogle Scholar
  79. Kumar S, Meena SW, Lal R, Yadav GS, Mitran T et al (2018) Role of legumes in soil carbon sequestration. In: Meena R, Das A, Yadav G, Lal R (eds) Legumes for soil health and sustainable management. Springer, Singapore, pp 109–138CrossRefGoogle Scholar
  80. Kuo YH, Bau HM, Quemener B, Khan JK, Lambein F (1995) Solid-state fermentation of Lathyrus sativus seeds using Aspergillus oryzae and Rhizopus oligosporus sp T-3 to eliminate the neurotoxin β-ODAP without loss of nutritional value. J Sci Food Agri 69:8189.  https://doi.org/10.1002/jsfa.2740690113CrossRefGoogle Scholar
  81. Kuo YH, Ikegami F, Lambein F (1998) Metabolic routes of β-(isoxazolin-5-on-2-yl)-l-alanine (bia), the precursor of the neurotoxin odap (β-n-oxalyl-l-α, β-diaminopropionic acid), in different legume seedlings. Phytochem 49(1):43–48.  https://doi.org/10.1016/s0031-9422(97)01001-7CrossRefGoogle Scholar
  82. Lambein F, Chowdhury B, Kuo YH (1999) Biochemistry of the Lathyrus toxins. Lathyrus Genet Resour Netw 8:60Google Scholar
  83. Lan G, Lan F, Sun X (2016) Use of dencichine in preparation of drug for treating thrombocytopenia. https://www.google.com/patents/US20160089351
  84. Lander ES, Green P, Abrahamson J, Barlow A, Daly M et al (1987) MAPMAKER: an interactive computer package for constructing primary linkage maps of experimental populations. Genomics 1(2):174–181CrossRefGoogle Scholar
  85. Ligerot Y, de Saint Germain A, Waldie T, Troadec C, Citerne S et al (2017) The pea branching RMS2 gene encodes the PsAFB4/5 auxin receptor and is involved in an auxin-strigolactone regulation loop. PLoS Genet 13(12):e1007089.  https://doi.org/10.1371/journal.pgen.1007089CrossRefPubMedPubMedCentralGoogle Scholar
  86. Lioi L, Galasso I (2013) Development of genomic simple sequence repeat markers from an enriched genomic library of grass pea (Lathyrus sativus L.). Plant Breed 132:649–653.  https://doi.org/10.1111/pbr.12093CrossRefGoogle Scholar
  87. Lioi L, Sparvoli F, Sonnante G, Laghetti G, Lupo F et al (2011) Characterization of Italian grass pea (Lathyrus sativus L.) germplasm using agronomic traits, biochemical and molecular markers. Genet Resour Crop Evol 58:425–437CrossRefGoogle Scholar
  88. Liu N, Shang W, Li C, Jia L, Wang X et al (2018) Evolution of the SPX gene family in plants and its role in the response mechanism to phosphorus stress. Open Biol 8:170231. http://dx.doi.org/10.1098/rsob.170231
  89. Lohr K, Camacho A, Vernooy R (2015) Seed systems–an overview. Farmers’ seed systems: the challenge of linking formal and informal seed systems. Deutsche Gesellschaft für Internationale Zusammenarbeit (GIZ) GmbH, Bonn, Germany, pp 3–7Google Scholar
  90. Louwaars NP, De Boef WS (2012) Integrated seed sector development in Africa: a conceptual framework for creating coherence between practices, programs, and policies. J Crop Improv 26:39–59CrossRefGoogle Scholar
  91. Louwaars NP, de Boef W, Edeme J (2013) Integrated seed sector development in Africa: a basis for seed policy and law. J Crop Improv 27:186–214CrossRefGoogle Scholar
  92. Malek MA (1998) Genetic resources of grass pea (Lathyrus sativus L.) in Bangladesh. In: Mathur PN, Rao VR, Arora RK (eds) Lathyrus Genetic Resources Network: proceedings of a IPGRI-ICARDA-ICAR Regional Working Group Meeting, National Bureau of Plant Genetic Resources, New Delhi, pp 1–6, 8–10 Dec 1997Google Scholar
  93. Malek MA, Gazipur B (1999) Genetic resources of grass pea (Lathyrus sativus L.) in Bangladesh. Lathyrus Genet Resour Netw 8:1Google Scholar
  94. Manly KF, Cudmore RH Jr, Meer JM (2001) Map Manager QTX, cross-platform software for genetic mapping. Mam Genome 12:930–932CrossRefGoogle Scholar
  95. Matsumura H, Urasaki N, Yoshida K, Krüger DH, Kahl G, Terauchi R (2012) Supersage: powerful serial analysis of gene expression. In: Jin H, Gassmann W (eds) RNA Abundance analysis. methods in molecular biology (methods and protocols), vol 883. Humana Press, Totowa, NJ.  https://doi.org/10.1007/978-1-61779-839-9_1
  96. McCallum CM, Comai L, Greene EA, Henikoff S (2000) Targeted screening for induced mutations. Nat Biotechnol 18:455–457CrossRefGoogle Scholar
  97. McClintock B (1984) The significance of responses of the genome to challenge. Science 226:792–801CrossRefGoogle Scholar
  98. Mendel G (1865) Versuche über P:flanzen-Hybriden. Verh. Naturforsch. Ver. Brünn. 4:3–47Google Scholar
  99. Mishra N, Sun L, Zhu X, Smith J, Srivastava AP et al (2017) Overexpression of the rice SUMO E3 ligase gene OsSIZ1 in cotton enhances drought and heat tolerance, and substantially improves fiber yields in the field under reduced irrigation and rainfed conditions. Plant Cell Physiol 58(4):735–746.  https://doi.org/10.1093/pcp/pcx032CrossRefPubMedPubMedCentralGoogle Scholar
  100. Muchero W, Roberts PA, Diop NN, Drabo I, Cisse N, Close TJ et al (2013) Genetic architecture of delayed senescence, biomass, and grain yield under drought stress in cowpea. PLoS ONE 8(7):e70041.  https://doi.org/10.1371/journal.pone.0070041CrossRefPubMedPubMedCentralGoogle Scholar
  101. Nerkar Y (1972) Induced variation and response to selection for low neurotoxin content in Lathyrus sativus. Indian J Genet 32(2):175–180Google Scholar
  102. Nosrati H, Hosseinpour-Feizi MA, Nikniazi M, Razban-Haghighi A (2012) Genetic variation among different accessions of Lathyrus sativus (Fabaceae) revealed by RAPDs. Bot Serb 36(1):41–47Google Scholar
  103. Okuda H, Lee SD, Matsuura Y, Zheng Y, Sekiya K, Takaku T et al (1990) Biological activities of non-saponin compounds isolated from Korean red ginseng. J Ginseng Res 14:157–161Google Scholar
  104. Padmajaprasad V, Kaladhar M, Bhat RV (1997) Thermal isomerisation of β-N-oxalyl-L-α, β-diaminopropionic acid, the neurotoxin in Lathyrus sativus, during cooking. Food Chem 59:77–80CrossRefGoogle Scholar
  105. Pandey SP, Yadav CR, Sah K, Pande S, Joshi PK (2000) Legumes in Nepal. In: Johansen C, Duxburv JM, Virmani SM, Gowda CLL, Pande S, Joshi PK (eds) Legumes in rice and wheat cropping systems of the Indo-Gangetic Plain—constraints and opportunities. International Crops Research institute for the Semi-Arid Tropics; Cornell University, Patancheru, Andhra Pradesh, India; Ithaca, NY, USA, pp 71–97Google Scholar
  106. Patto MCV, Rubiales D (2014) Lathyrus diversity: available resources with relevance to crop improvement—L. sativus and L. cicero as case studies. Ann Bot 113:895–908.  https://doi.org/10.1093/aob/mcu024CrossRefGoogle Scholar
  107. Patto MCV, Amarowicz R, Aryee AN, Boye JI, Chung HJ et al (2015) Achievements and challenges in improving the nutritional quality of food legumes. Crit Rev Plant Sci 34(1–3):105–143.  https://doi.org/10.1080/07352689.2014.897907CrossRefGoogle Scholar
  108. Patto MCV, Mecha E, Pereira AB, Leitão ST, Alves ML, Bronze MR (2018) Deciphering grain legumes quality riddle: the genomics of bioactive compounds. In: Brazauskas G, Statkevičiūtė G, Jonavičienė K (eds) Breeding grasses and protein crops in the era of genomics. Springer, Cham.  https://doi.org/10.1007/978-3-319-89578-9_21
  109. Plett JM, Wilkins O, Campbell MM, Ralph SG, Regan S (2010) Endogenous overexpression of Populus MYB186 increases trichome density, improves insect pest resistance, and impacts plant growth. Plant J 64:419–432.  https://doi.org/10.1111/j.1365-313X.2010.04343.xCrossRefPubMedGoogle Scholar
  110. Ponnaiah M, Shiferaw E, Pe ME, Porceddu E (2011) Development and application of EST-SSRs for diversity analysis in Ethiopian grass pea. Plant Genet Resour 9:276–280CrossRefGoogle Scholar
  111. Puchta H (2016) Using CRISPR/Cas in three dimensions: towards synthetic plant genomes, transcriptomes and epigenomes. Plant J 87:5–15CrossRefGoogle Scholar
  112. Rahman MM, Kumar J, Rahaman MA, Afzal MA (1995) Natural outcrossing in Lathyrus sativus L. Indian J Genet 55(2):204–207Google Scholar
  113. Ramachandran S, Bairagi A, Ray AK (2005) Improvement of nutritive value of grass pea (Lathyrus sativus) seed meal in the formulated diets for rohu, Labeo rohita (Hamilton) fingerlings after fermentation with a fish gut bacterium. Bioresour Technol 96:1465–1472.  https://doi.org/10.1016/j.biortech.2004.12.002CrossRefPubMedGoogle Scholar
  114. Rao SLN (2011) A look at the brighter facets of beta-N-oxalyl-l-alpha, beta-diaminopropionic acid, homoarginine and the grass pea. Food Chem Toxicol 49:620–622.  https://doi.org/10.1016/j.fct.2010.06.054CrossRefPubMedGoogle Scholar
  115. Rao SC, Northup BK (2011) Growth and nutritive value of grass pea in Oklahoma. Agron J 103:1692–1696.  https://doi.org/10.2134/agronj2011.0178CrossRefGoogle Scholar
  116. Rao SLN, Adiga PR, Sarma P (1964) The isolation and characterization of β-Noxalyl-L-α, β-diaminopropionic acid, a neurotoxin from the seeds of Lathyrus sativus. Biochem 3:432–436CrossRefGoogle Scholar
  117. Resende RT, de Resende MDV, Azevedo CF, Fonseca E, Silva F, Melo LC et al (2018) Genome-wide association and regional heritability mapping of plant architecture, lodging and productivity in Phaseolus vulgaris. Genes Genomes Genet 8(8):2841–2854.  https://doi.org/10.1534/g3.118.200493
  118. Roy PK, Barat GK, Mehta SL (1992) In vitro plant regeneration from callus derived from root explants of Lathyrus sativus. Plant Cell Tiss Organ Cult 29:135.  https://doi.org/10.1007/BF00033618CrossRefGoogle Scholar
  119. Roy PK, All K, Gupta A, Barat GK, Mehta SL (1993) β-N-Oxalyl-L-α, β-diaminopropionic acid in somaclones derived from internode explants of Lathyrus sativus. J Plant Biochem Biotechnol 2:9.  https://doi.org/10.1007/BF03262914CrossRefGoogle Scholar
  120. Rubiales D, Fondevilla S, Chen W, Gentzbittel L, Higgins TJ et al (2015) Achievements and challenges in legume breeding for pest and disease resistance. Crit Rev Plant Sci 34:195–236CrossRefGoogle Scholar
  121. Rybiński W (2003) Mutagenesis as a tool for improvement of traits in grasspea (Lathyrus sativus L.). Lathyrus Lathyrism Newsl 27–31Google Scholar
  122. Rybinski W, Blaszczak W, Fornal J (2006) Seed microstructure and genetic variation of characters in selected grass-pea mutants (Lathyrus sativus L.). Intl Agrophys 20:317Google Scholar
  123. Santos C, Almeida NF, Alves ML, Horres R, Krezdorn N et al (2018) First genetic linkage map of Lathyrus cicera based on RNA sequencing-derived markers: Key tool for genetic mapping of disease resistance. Hort Res 5:45CrossRefGoogle Scholar
  124. Sarker A, Fikre A, El-Moneim AMA, Nakkoul H, Singh M (2017) Reducing anti-nutritional factor and enhancing yield with advancing time of planting and zinc application in grass pea in Ethiopia. J Sci Food Agri 98(1):27–32.  https://doi.org/10.1002/jsfa.8433CrossRefGoogle Scholar
  125. Shi C, Navabi A, Yu K (2011) Association mapping of common bacterial blight resistance QTL in Ontario bean breeding populations. BMC Plant Biol 11:52.  https://doi.org/10.1186/1471-2229-11-52CrossRefPubMedPubMedCentralGoogle Scholar
  126. Shiferaw E, Pè ME, Porceddu E, Ponnaiah M (2012) Exploring the genetic diversity of ethiopian grass pea (Lathyrus sativus L.) using EST-SSR markers. Mol Breed 30:789–797CrossRefGoogle Scholar
  127. Singh SS, Rao SLN (2013) Lessons from neurolathyrism: a disease of the past & the future of Lathyrus sativus (Khesari dal). Indian J Med Res 138:32–37PubMedPubMedCentralGoogle Scholar
  128. Singh AK, Singh SS, Prakash V, Kumar S, Dwivedi SK (2015) Pulses production in India: present status, bottleneck and way forward. J Agri Search 2:75–83Google Scholar
  129. Singh A, Septiningsih EM, Balyan HS, Singh NK, Rai V (2017) Genetics, physiological mechanisms and breeding of flood-tolerant rice (Oryza sativa L.). Plant Cell Physiol 58:185–197.  https://doi.org/10.1093/pcp/pcw206CrossRefPubMedGoogle Scholar
  130. Sita K, Sehgal A, Hanumantha Rao B, Nair RM, Vara Prasad PV, Kumar S et al (2017) Food legumes and rising temperatures: effects, adaptive functional mechanisms specific to reproductive growth stage and strategies to improve heat tolerance. Front Plant Sci 8:1658.  https://doi.org/10.3389/fpls.2017.01658CrossRefPubMedPubMedCentralGoogle Scholar
  131. Skiba B, Ford R, Pang EC (2004) Construction of a linkage map based on a Lathyrus sativus backcross population and preliminary investigation of QTLs associated with resistance to ascochyta blight. Theor Appl Genet 109:1726–1735CrossRefGoogle Scholar
  132. Smartt J (1984) Evolution of grain legumes. I. Mediterranean pulses. Exp Agric 20(4):275–296.  https://doi.org/10.1017/S0014479700017968
  133. Snoad B (1981) Plant form, growth rate and relative growth rate compared in conventional, semi-leafless and leafless peas. Sci Hort 14:9–18.  https://doi.org/10.1016/0304-4CrossRefGoogle Scholar
  134. Songstad DD, Petolino JF, Voytas DF, Reichert NA (2017) Genome editing of plants. Crit Rev Plant Sci 36(1):1–23.  https://doi.org/10.1080/07352689.2017.1281663CrossRefGoogle Scholar
  135. Stanke M, Keller O, Gunduz I, Hayes A, Waack S, Morgenstern B (2006) AUGUSTUS: ab initio prediction of alternative transcripts. Nucl Acids Res 34 supp_2(1):W435–W439.  https://doi.org/10.1093/nar/gkl200
  136. Sun XL, Yang T, Guan JP, Ma Y, Jiang JY, Cao R et al (2012) Development of 161 novel EST-SSR markers from Lathyrus sativus (Fabaceae). Amer J Bot 99(10):e379–e390.  https://doi.org/10.3732/ajb.1100346CrossRefGoogle Scholar
  137. Talukdar D (2009a) Dwarf mutations in grass pea (Lathyrus sativus L.): origin, morphology, inheritance and linkage studies. J Genet 88:165–175CrossRefGoogle Scholar
  138. Talukdar D (2009b) Recent progress on genetic analysis of novel mutants and aneuploid research in grass pea (Lathyrus sativus L.). Afr J Agri Res 14:1549–1559Google Scholar
  139. Talukdar D, Biswas AK (2008) Seven different primary trisomics in grass pea (Lathyrus sativus L.). II. Pattern of transmission. Cytologia 73:129–136CrossRefGoogle Scholar
  140. Tan GZ, Das Bhowmik SS, Hoang TM, Karbaschi MR, Johnson AA et al (2017) Finger on the pulse: pumping iron into chickpea. Front Plant Sci 8:1755CrossRefGoogle Scholar
  141. Tavoletti S, Iommarini L (2007) Molecular marker analysis of genetic variation characterizing a grass pea (Lathyrus sativus) collection from central Italy. Plant Breed 126:607–611CrossRefGoogle Scholar
  142. Tayeh N, Aubert G, Pilet-Nayel ML, Lejeune-Hénaut I, Warkentin TD, Burstin J (2015) Genomic tools in pea breeding programs: status and perspectives. Front Plant Sci 6:1037.  https://doi.org/10.3389/fpls.2015.01037CrossRefPubMedPubMedCentralGoogle Scholar
  143. Tiwari KR, Campbell CG (1996) Inheritance of seed weight in grasspea (Lathyrus sativus L.). Faba Bean Inf Serv 38–39:30–33Google Scholar
  144. Townsend CC, Guest E (1974) Flora of Iraq: Leguminales, vol 3. Ministry of Agriculture and Agrarian Reforms, Baghdad, IraqGoogle Scholar
  145. Van Ooijen JW (2006) JoinMap 4, software for the calculation of genetic linkage maps in experimental populations. Kyazma B. V., Wageningen, NetherlandsGoogle Scholar
  146. Visser B (2013) The moving scope of annex 1. In: Halewood M, Lopez I, Noriega SL (eds) Crop genetic resources as a global commons. Routledge, Oxon, UK, pp 265–282. https://www.bioversityinternational.org/fileadmin/user_upload/online_library/publications/pdfs/Crop_genetic_Resources_global_commons/14.crops_list_under_multilater_system.pdf. Accessed 12 Sep 2018
  147. Wahiduzzaman MIA, Yamauchi A, Kono Y (1996) Root system structure of six food legume species: inter- and intraspecific variations. Jpn J Crop Sci 65(1):131–140.  https://doi.org/10.1626/jcs.65.131CrossRefGoogle Scholar
  148. Wang TL, Bogracheva TY, Hedley CL (1998) Starch: as simple as A, B, C? J Exp Bot 49:481–502Google Scholar
  149. Wang TL, Uauy C, Robson F, Till B (2012) TILLING in extremis. Plant Biotechnol J 10:761–772.  https://doi.org/10.1111/j.1467-7652.2012.00708.xCrossRefPubMedGoogle Scholar
  150. Wang Z, Yang JY, Chen Q (2014) Development of dencichine plus Yunnan Baiyao band-aid. In: Advanced Materials Research, vol 881–883, pp 364–367.  https://doi.org/10.4028/www.scientific.net/AMR.881-883.364
  151. Wang F, Yang T, Burlyaeva M, Li L, Jiang J, Fang L et al (2015) Genetic diversity of grasspea and its relative species revealed by SSR markers. PLoS ONE 10(3):e0118542.  https://doi.org/10.1371/journal.pone.0118542CrossRefPubMedPubMedCentralGoogle Scholar
  152. Weller JL, Ortega R (2015) Genetic control of flowering time in legumes. Front Plant Sci 6:207.  https://doi.org/10.3389/fpls.2015.00207CrossRefPubMedPubMedCentralGoogle Scholar
  153. Xiao N, Gao Y, Qian H, Gao Q, Wu Y, Zhang et al (2018) Identification of genes related to cold tolerance and a functional allele that confers cold tolerance. Plant Physiol 177:1108–1123.  https://doi.org/10.1104/pp.18.00209
  154. Xu Q, Liu F, Chen P, Jez JM, Krishnan HB (2017) β-N-Oxalyl-l-α, β-diaminopropionic Acid (β-ODAP) Content in Lathyrus sativus: the integration of nitrogen and sulfur metabolism through β-cyanoalanine synthase. Intl J Mol Sci 18:526.  https://doi.org/10.3390/ijms1803052CrossRefGoogle Scholar
  155. Xu Q, Liu F, Qu R, Gillman JD, Bi C et al (2018) Transcriptomic profiling of Lathyrus sativus L. metabolism of β-ODAP, a neuroexcitatory amino acid associated with neurodegenerative lower limb paralysis. Plant Mol Biol Rep 1–12.  https://doi.org/10.1007/s11105-018-1123-x
  156. Yan ZY, Spencer PS, Li ZX, Liang YM, Wang YF et al (2006) Lathyrus sativus (grass pea) and its neurotoxin ODAP. Phytochem 67(2):107–121.  https://doi.org/10.1016/j.phytochem.2005.10.022CrossRefGoogle Scholar
  157. Yang HM, Zhang XY (2005) Considerations on the reintroduction of grass pea in China. Lathyrus Lathyrism Newsl 4:22–26Google Scholar
  158. Yang T, Chaudhuri S, Yang L, Du L, Poovaiah BW (2010) A calcium/calmodulin-regulated member of the receptor-like kinase family confers cold tolerance in plants. J Biol Chem 285:7119–7126CrossRefGoogle Scholar
  159. Yang T, Jiang J, Burlyaeva M, Hu J, Coyne CJ, Kumar S et al (2014) Large-scale microsatellite development in grasspea (Lathyrus sativus L.), an orphan legume of the arid areas. BMC Plant Biol 14:65.  https://doi.org/10.1186/1471-2229-14-65. PMID: 24635905
  160. Yigzaw Y, Gorton L, Solomon T, Akalu G (2004) Fermentation of seeds of tef (Eragrostis teff), grass-pea (Lathyrus sativus), and their mixtures: aspects of nutrition and food safety. J Agri Food Chem 52:1163–1169.  https://doi.org/10.1021/jf034742yCrossRefGoogle Scholar
  161. Zhang J, Zhou X, Xu Y, Yao M, Xie F et al (2016) Soybean SPX1 is an important component of the response to phosphate deficiency for phosphorus homeostasis. Plant Sci 248:82–91.  https://doi.org/10.1016/j.plantsci.2016.04.010CrossRefPubMedGoogle Scholar

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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.John Innes Centre, Norwich Research ParkNorwichUK
  2. 2.Biosciences Eastern and Central Africa - International Livestock Research Institute HubNairobiKenya
  3. 3.South Asia & China Program & Principal Food Legume Breeder, International Center for Agricultural Research in the Dry Areas (ICARDA)New DelhiIndia
  4. 4.Institute of Crop Sciences, Chinese Academy of Agricultural SciencesBeijingChina

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