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How Are These Devices Manufactured?

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Paper-based Diagnostics

Abstract

Paper-based devices are a portable and low-cost technology alternative among conventional analytical tools for point-of-care testing that have been growing in popularity due to their versatility and ease of use. Since their introduction in 2007, different methods to fabricate such devices have been proposed in literature, including photolithography, plotting, inkjet printing, wax printing, and stamping, among other methods, each with its unique advantages and drawbacks. Here, we present the most common current fabrication methods of microfluidic paper-based analytical devices (μPADs) in two and three dimensions, comparing their processes of fabrication, resolution of the features, and costs associated with their manufacture presenting insights towards the most adequate choice of fabrication method.

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Acknowledgements

The authors would like to thank the funding agencies FAPESP (Grant No. 2011/13997-8), CNPq (Grant No. 205453/2014-7) by the scholarships and the financial support to the Instituto Nacional de Ciência e Tecnologia de Bioanalítica—INCTBio (FAPESP Grant Nr. 2008/57805-2/CNPq Grant Nr. 573672/2008-3), the Georgia Institute of Technology (Georgia Tech), and the State of Georgia, USA. The authors declare having no competing financial interests.

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Authors and Affiliations

  1. School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA, USA

    Giorgio Gianini Morbioli & Amanda M. Stockton

  2. Instituto de Química de São Carlos, Universidade de São Paulo, São Carlos, SP, Brazil

    Thiago Mazzu-Nascimento & Emanuel Carrilho

  3. Instituto Nacional de Ciência e Tecnologia de Bioanalítica, Campinas, SP, Brazil

    Thiago Mazzu-Nascimento & Emanuel Carrilho

Authors
  1. Giorgio Gianini Morbioli
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  2. Thiago Mazzu-Nascimento
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  3. Amanda M. Stockton
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  4. Emanuel Carrilho
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Correspondence to Emanuel Carrilho .

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  1. Council for Scientific and Industrial Research, Pretoria, South Africa

    Kevin J. Land

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Morbioli, G.G., Mazzu-Nascimento, T., Stockton, A.M., Carrilho, E. (2019). How Are These Devices Manufactured?. In: Land, K. (eds) Paper-based Diagnostics. Springer, Cham. https://doi.org/10.1007/978-3-319-96870-4_4

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  • DOI: https://doi.org/10.1007/978-3-319-96870-4_4

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