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Robotic Myomectomy

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Robotic-Assisted Minimally Invasive Surgery
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Abstract

Despite irrefutable evidence of the superiority of minimally invasive myomectomy over open abdominal myomectomy, laparoscopic myomectomy has an unacceptably low adoption in most countries. Robotic myomectomy is a proven solution to this unsustainable status quo. Introduced in 2004, this operation has a long safety record, allows the performance of a truly microsurgical operation, and can be applied to most clinical scenarios, thereby limiting the need for open myomectomy.

This chapter separates the myomectomy operation in its fundamental components and critically analyzes the impact of robotic technology on each one. It also provides a practical checklist for the robotic surgeon so that every element is optimized for success. Preoperative imaging, pharmacological preparation, port placement, and technical details are covered in detail, as are more challenging scenarios including very large myomas, retroperitoneal myomas, and surgical options for minimal cosmetic impact. Basic aspects of contained tissue extraction are also reviewed.

As robotic surgical platforms continue to evolve, and will soon proliferate beyond the current general expectations of the medical community, this chapter aims to provide a current general strategy for robotic myomectomy that is likely to remain relevant for the users of future generations of surgical robots.

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References

  1. Bortoletto P, Hariton E, Gargiulo AR. The evolution of myomectomy: from laparotomy to minimally invasive surgery. BJOG. 2018;125(5):586.

    Article  Google Scholar 

  2. Liu G, Zolis L, Kung R, Melchior M, Singh S, Cook EF. The laparoscopic myomectomy: a survey of Canadian gynaecologists. J Obstet Gynaecol Can. 2010;32(2):139–48.

    Article  Google Scholar 

  3. Seracchioli R, Rossi S, Govoni F, et al. Fertility and obstetric outcome after laparoscopic myomectomy of large myomata: a randomized comparison with abdominal myomectomy. Hum Reprod. 2000;15:2663–8.

    Article  CAS  Google Scholar 

  4. Seracchioli R, Manuzzi L, Vianello F, et al. Obstetric and delivery outcome of pregnancies achieved after laparoscopic myomectomy. Fertil Steril. 2006;86:159–65.

    Article  Google Scholar 

  5. Mais V, Ajossa S, Guerriero S, Mascia M, Solla E, Melis GB. Laparoscopic versus abdominal myomectomy: a prospective, randomized trial to evaluate benefits in early outcome. Am J Obstet Gynecol. 1996;174:654–8.

    Article  CAS  Google Scholar 

  6. Holzer A, Jirecek ST, Illievich UM, Huber J, Wenzl RJ. Laparoscopic versus open myomectomy: a double-blind study to evaluate postoperative pain. Anesth Analg. 2006;102:1480–4.

    Article  CAS  Google Scholar 

  7. Practice Committee of the American Society of Reproductive Medicine. Pathogenesis, consequences, and control of peritoneal adhesions in gynecologic surgery. Fertil Steril. 2007;88:21.

    Article  Google Scholar 

  8. Jin C, Hu Y, Chen XC, Zheng FY, Lin F, Zhou K, Chen FD, Gu HZ. Laparoscopic versus open myomectomy – a meta-analysis of randomized controlled trials. Eur J Obstet Gynecol Reprod Biol. 2009;145:14–21.

    Article  Google Scholar 

  9. Puchino N, Litta P, Freschi L, Russo M, Santoro AN, Gadducci A, Cela V. Comparison of the initial surgical experience with robotic and laparoscopic myomectomy. Int J Med Rob. 2014;10(2):208–12.

    Article  Google Scholar 

  10. Kumakiri J, Kikuchi I, Kitade M, Matsuoka S, Kono A, Ozaki R, Takeda S. Association between uterine repair at laparoscopic myomectomy and postoperative adhesions. Acta Obstet Gynecol Scand. 2012;91(3):331–7.

    Article  Google Scholar 

  11. Pitter MC, Gargiulo AR, Bonaventura LM, Lehman JS, Srouji SS. Pregnancy outcomes following robot-assisted myomectomy. Hum Reprod. 2013;28:99–108.

    Article  Google Scholar 

  12. Patzkowsky KE, As-Sanie S, Smorgick N, Song AH, Advincula AP. Perioperative outcomes of robotic vs. laparoscopic hysterectomy for benign disease. JSLS. 2013;17(1):100–6.

    Article  Google Scholar 

  13. Choussein S, Srouji SS, Missmer SA, Farland LV, Gargiulo AR. Perioperative outcomes and complications of robot-assisted laparoscopic myomectomy (RALM). J Minim Invasive Gynecol. 2015;22(6S):S70.

    Article  CAS  Google Scholar 

  14. Advincula AP, Song A, Burke W, Reynolds RK. Preliminary experience with robot-assisted laparoscopic myomectomy. J Am Assoc Gynecol Laparosc. 2004;11(4):511–8.

    Article  Google Scholar 

  15. Gargiulo AR, Srouji SS, Missmer SA, Correia KF, Vellinga TT, Einarsson JI. Robot-assisted laparoscopic myomectomy compared with standard laparoscopic myomectomy. Obstet Gynecol. 2012;120(2 Pt 1):284–91. Erratum in: Obstet Gynecol. 2013;122(3):698.

    Article  Google Scholar 

  16. Bedient CE, Magrina JF, Noble BN, Kho RM. Comparison of robotic and laparoscopic myomectomy. Am J Obstet Gynecol. 2009;201(6):566 e1–5.

    Article  Google Scholar 

  17. Nezhat C, Lavie O, Hsu S, Watson J, Barnett O, Lemire M. Robotic-assisted laparoscopic myomectomy compared with standard laparoscopic myomectomy-a retrospective matched control study. Fertil Steril. 2009;91(2):556–9.

    Article  Google Scholar 

  18. Pitter M, Srouji S, Gargiulo A, Kardos L, Seshadri-Kreaden U, Hubert HB, Weitzman GA. Fertility and symptom relief following robot-assisted laparoscopic myomectomy. Obstet Gynecol Int. 2015. https://doi.org/10.1155/2015/967568. Epub 2015 Apr 19.

    Article  Google Scholar 

  19. Advincula AP, Xu X, Goudeau S, Ransom SB. Robot-assisted laparoscopic myomectomy versus abdominal myomectomy: a comparison of short-term surgical outcomes and immediate costs. J Minim Invasive Gynecol. 2007;14(6):698–705.

    Article  Google Scholar 

  20. Barakat EE, Bedaiwy MA, Zimberg S, Nutter B, Nosseir M, Falcone T. Robotic-assisted, laparoscopic, and abdominal myomectomy: a comparison of surgical outcomes. Obstet Gynecol. 2011;117(2 Pt 1):256–29.

    Article  Google Scholar 

  21. Gargiulo AR. Fertility preservation and the role of robotics. Clin Obstet Gynecol. 2011;54(3):431–48.

    Article  Google Scholar 

  22. Lipskind ST, Gargiulo AR. Computer-assisted laparoscopy in fertility preservation and reproductive surgery. J Minim Invasive Gynecol. 2013;20(4):435–45.

    Article  Google Scholar 

  23. Gargiulo AR. Computer-assisted reproductive surgery: why it matters to reproductive endocrinology and infertility subspecialists. Fertil Steril. 2014;102(4):911–21.

    Article  Google Scholar 

  24. Lewis EI, Gargiulo AR. Uterine fibroids in the setting of infertility: when to treat, how to treat. Curr Obstet Gynecol Rep. 2017;6(1):1–10.

    Article  Google Scholar 

  25. Fanfano F, Reistano S, Rossitto C, Gueli Alletti S, Costantini B, Monterossi G, Cappuccio S, Perrone E, Scambia G. Total laparoscopic (S-LPS) versus TELELAP ALF-X robotic-assisted hysterectomy: a case-control study. J Minim Invasive Gynecol. 2016;23(6):933–8.

    Article  Google Scholar 

  26. Shwayder J, Sakhel K. Imaging for uterine myomas and adenomyosis. J Minim Invasive Gynecol. 2014;21(3):362–76.

    Article  Google Scholar 

  27. Moghadam R, Lathi RB, Shahmohamady B, Saberi NS, Nezhat CH, Nezhat F, Nezhat C. Predictive value of magnetic resonance imaging in differentiating between leiomyoma and adenomyosis. JSLS. 2006;10(2):216–9.

    PubMed  PubMed Central  Google Scholar 

  28. Bhave Chittawar P, Franik S, Pouwer AW, Farquhar C. Minimally invasive surgical techniques versus open myomectomy for uterine fibroids. Cochrane Database Syst Rev. 2014;10:CD004638.

    Google Scholar 

  29. Angioli R, Battista C, Terranova C, Zullo MA, Sereni MI, Cafà EV, Panici PB. Intraoperative contact ultrasonography during open myomectomy for uterine fibroids. Fertil Steril. 2010;94(4):1487–90.

    Article  Google Scholar 

  30. Battita C, Capriglione S, Guzzo F, Luvero D, Sadun B, Cafa EV, Sereni MI, Terranova C, Plotti F, Angioli R. The challenge of preoperative identification of uterine myomas: is ultrasound trustworthy? A prospective cohort study. Arch Gynecol Obstet. 2016;293(6):1235–41.

    Article  Google Scholar 

  31. Parker WH, Einarsson J, Istre O, Dubuisson JB. Risk factors for uterine rupture after laparoscopic myomectomy. J Minim Invasive Gynecol. 2010;17(5):551–4.

    Article  Google Scholar 

  32. Quaas AM, Einarsson JI, Srouji SS, Gargiulo AR. Robotic myomectomy: a review of indications and techniques. Rev Obstet Gynecol. 2010;3(4):185–91.

    PubMed  PubMed Central  Google Scholar 

  33. Choussein S, Srouji SS, Farland LV, Gargiulo AR. Flexible carbon dioxide laser fiber versus ultrasonic scalpel in robot-assisted laparoscopic myomectomy. J Minim Invasive Gynecol. 2015;22(7):1183–90.

    Article  Google Scholar 

  34. Bailey AP, Lancerotto L, Gridley C, Orgill DP, Nguyen H, Pescarini E, Lago G, Gargiulo AR. Greater surgical precision of a flexible carbon dioxide laser fiber compared to monopolar electrosurgery in porcine myometrium. J Minim Invasive Gynecol. 2014;21(6):1103–9.

    Article  Google Scholar 

  35. Tinelli A, Malvasi A, Hurst BS, Tsin DA, Davila F, Dominguez G, Dell’edera D, Cavallotti C, Negro R, Gustapane S, Teigland CM, Lettler L. Surgical management of neurovascular bundle in uterine fibroid pseudocapsule. JSLS. 2012;16(1):119–29.

    Article  Google Scholar 

  36. Bedaiwy MA, Zhang A, Henry D, Falcone T, Soto E. Surgical anatomy of supraumbilical port placement: implications for robotic and advanced laparoscopic surgery. Fertil Steril. 2015;103(4):e33.

    Article  Google Scholar 

  37. De Milliano I, Twisk M, Ket JC, Huirne JA, Hehenkamp WJ. Pre-treatment with GnRHa or ulipristal acetate prior to laparoscopic and laparotomic myomectomy: a systematic review and meta-analysis. PLoS One. 2017;12(10):e0186158. https://doi.org/10.1371/journal.pone.0186158. eCollection 2017.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  38. Cordier W, Steenkamp V. Herbal remedies affecting coagulation: a review. Pharm Biol. 2012;50(4):443–52.

    Article  CAS  Google Scholar 

  39. Celik H, Sapmaz E. Use of a single preoperative dose of misoprostol is efficacious for patients who undergo abdominal myomectomy. Fertil Steril. 2003;79:1207–10.

    Article  Google Scholar 

  40. Ragab A, Khaiary M, Badawy A. The use of single versus double dose of intra-vaginal prostaglandin E2 “misoprostol” prior to abdominal myomectomy: a randomized controlled clinical trial. J Reprod Infertil. 2014;15:152–6.

    PubMed  PubMed Central  Google Scholar 

  41. Cohen SL, Senapati S, Gargiulo AR, Srouji SS, Tu FF, Solnik J, Hur HC, Vitonis A, Jonsdottir GM, Wang KC, Einarsson JI. Dilute versus concentrated vasopressin administration during laparoscopic myomectomy: a randomized controlled trial. BJOG. 2017;124(2):262–8.

    Article  CAS  Google Scholar 

  42. Topsoee MF, Settnes A, Ottesen B, Bergholt T. A systematic review and meta-analysis of the effect of prophylactic tranexamic acid treatment in major benign uterine surgery. Int J Gynaecol Obstet. 2017;136(2):120–7.

    Article  CAS  Google Scholar 

  43. Jansen JA, Lameijer JRC, Snoeker BAM. Combined intravenous, topical and oral tranexamic acid administration in total knee replacement: evaluation of safety in patients with previous thromboembolism and effect on hemoglobin level and transfusion rate. Knee. 2017;24(5):1206–12.

    Article  Google Scholar 

  44. U.S. Food and Drugs Administration. UPDATED laparoscopic uterine power morcellation in hysterectomy and myomectomy: FDA safety communication. November 24, 2014. http://www.fda.gov/MedicalDevices/Safety/AlertsandNotices/ucm424443.htm.

  45. U.S. Food and Drugs Administration. FDA in brief: FDA releases new findings on the risks of spreading hidden uterine cancer through the use of laparoscopic power morcellators. December 14, 2017. https://www.fda.gov/NewsEvents/Newsroom/FDAInBrief/ucm589137.htm.

  46. Srouji SS, Kaser DK, Gargiulo AR. Techniques for contained morcellation in gynecologic surgery. Fertil Steril. 2015;103(40):e34.

    Article  Google Scholar 

  47. Clark NV, Cohen SL. Tissue extraction techniques during laparoscopic uterine surgery. J Minim Invasive Gynecol. 2018;25(2):251–6.

    Article  Google Scholar 

  48. Cohen A, Tulandi T. Long-term sequelae of unconfined morcellation during laparoscopic gynecological surgery. Maturitas. 2017;97:1–5.

    Article  Google Scholar 

  49. Harris JA, Swenson CW, Uppal S, Kamdar N, Mahnert N, As-Sanie S, Morgan DM. Practice patterns and postoperative complications before and after US Food and Drug Administration safety communication on power morcellation. Am J Obster Gynecol. 2016;214(1):98.e1–98.e13.

    Article  Google Scholar 

  50. Gargiulo AR, Lewis EI, Kaser DJ, Srouji SS. Robotic single site myomectomy: a step by step tutorial. Fertil Steril. 2015;104(5):e13.

    Article  Google Scholar 

  51. Lewis EI, Srouji SS, Gargiulo AR. Robotic single site myomectomy: initial report and technique. Fertil Steril. 2015;103:1370–7.

    Article  Google Scholar 

  52. Bush AJ, Morris SN, Millham FH, et al. Women’s preferences for minimally invasive incisions. J Minim Invasive Gynecol. 2011;18:640–3.

    Article  Google Scholar 

  53. Yeung PP Jr, Bolden CR, Westreich D, et al. Patient preferences of cosmesis for abdominal incisions in gynecologic surgery. J Minim Invasive Gynecol. 2013;20:79–84.

    Article  Google Scholar 

  54. Goebel K, Goldberg JM. Women’s preference of cosmetic results after gynecologic surgery. J Minim Invasive Gynecol. 2014;21:64–7.

    Article  Google Scholar 

  55. Hawa N, Robinson J, Chahine BE. Combined preoperative angiography transient uterine artery embolization makes laparoscopic surgery for massive myomatous uteri a reasonable option: case reports. J Minim Invasive Gynecol. 2012;19(3):386–90.

    Article  Google Scholar 

  56. Liu L, Li Y, Xu H, Chen Y, Zhang G, Liang Z. Laparoscopic transient uterine artery occlusion and myomectomy for symptomatic uterine myoma. Fertil Steril. 2011;95(1):254–8.

    Article  Google Scholar 

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Correspondence to Antonio R. Gargiulo .

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Gargiulo, A.R. (2019). Robotic Myomectomy. In: Tsuda, S., Kudsi, O. (eds) Robotic-Assisted Minimally Invasive Surgery . Springer, Cham. https://doi.org/10.1007/978-3-319-96866-7_26

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  • DOI: https://doi.org/10.1007/978-3-319-96866-7_26

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  • Online ISBN: 978-3-319-96866-7

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