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Awake Craniotomy: Cortical and Subcortical Mapping for Glioma Resection

  • Shawn L. Hervey-JumperEmail author
  • Mitchel S. Berger
Chapter
  • 677 Downloads

Abstract

Over 70,000 patients are diagnosed each year with a glioma, and the majority of these tumors are within areas of the brain with presumed functional significance. It has been well established that extent of tumor resection impacts both overall and progression-free survival. Direct stimulation of the cerebral cortex was first employed by Foerster in 1931 and later popularized by Penfield and Ojemann. Intraoperative mapping is the gold standard approach for the identification and preservation of functional areas of the brain. This chapter outlines the evidence supporting the extent of resection for low- and high-grade gliomas, including procedural steps and technical nuances to maximize success and minimize perioperative morbidity.

Keywords

Glioma Glioblastoma Extent of resection Brain mapping DTI Diffusion tensor imaging Tractography 

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Authors and Affiliations

  1. 1.Department of Neurological SurgeryUniversity of California San Francisco Medical CenterSan FranciscoUSA

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