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Selenium pp 393–412Cite as

Selenium Nanoparticles: Biomedical Applications

Part of the Molecular and Integrative Toxicology book series (MOLECUL)

Abstract

Nanotechnology has introduced nanoparticulate form of selenium for a wide variety of applications. Due to exceptional catalytic, photoreactive, biocidal, anticancer, and antioxidant properties, selenium nanoparticles (SeNPs) attract considerable interest for use in antimicrobial coatings, nutritional supplements, nanotherapeutics, diagnostics, and medical devices, as well as in other applications such as rectifiers, photocopiers, xerography, and solar cells. Preparation and synthesis of SeNPs may be conducted following different physical, chemical, or biological techniques. Depending on the selected synthetic route, physicochemical properties of final SeNPs can be controlled by careful setup of experimental conditions including reactant concentrations, reaction temperature and pH, time for preparation, addition of catalysts, coating agent for surface stabilization, etc. Any application of SeNPs should be ascertained by the risk versus benefit ratio profiling. Implementation of safe-by-design concept, which is designed to ensure safety for humans and the environment, would help in timely identification of all risks related to the innovation processes and value chain of SeNPs.

Keywords

  • Nanoparticles
  • Synthesis
  • Anticancer
  • Drug resistance
  • Antimicrobial
  • Antioxidant
  • Safe-by-design

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  1. Institute for Medical Research and Occupational Health, Zagreb, Croatia

    Ivana Vinković Vrček

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  1. Research Unit: Analytical BioGeoChemistry, Helmholtz Zentrum München – German Research Center for Environmental Health GmbH, Neuherberg, Germany

    Prof. Dr. Bernhard Michalke

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Vinković Vrček, I. (2018). Selenium Nanoparticles: Biomedical Applications. In: Michalke, B. (eds) Selenium. Molecular and Integrative Toxicology. Springer, Cham. https://doi.org/10.1007/978-3-319-95390-8_21

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