Overview of Cell Signaling Pathways in Cancer
There are many different signaling pathways that contribute to development and cellular homeostasis. In diseases, especially cancer, development components of these pathways often become mutated or overexpressed causing dysregulation of cellular signaling. This chapter provides an overview of the key pathways involved in tumor development and progression and studies some of the complications associated with therapeutic targeting, namely, signaling cross talk and biomarker identification.
KeywordsEGFR Cancer Cell signaling Biomarkers Therapeutic targets MAPK
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